According to the National Alopecia Areata Foundation, Alopecia Areata (AA) is a common autoimmune skin disease, which causes hair loss on the scalp, face, and at times on other areas of the body. The affected hair follicles are attacked by a person’s immune system (white blood cells), which results in seizing of the hair growth stage. Hair follicles remain alive, and hair can regrow at any time in Alopecia Areata. Alopecia Areata usually begins with one or more patches which may be small, round, smooth on the scalp that can progress to total scalp hair loss or complete body hair loss. Genetic predisposition and environmental factors increase the chances of developing Alopecia Areata.
The histopathological feature of alopecia areata is an inflammatory cell infiltrate concentrated in and around the bulbar region of anagen hair follicles. The hair follicle matrix epithelium that is undergoing early cortical differentiation seems to be the primary target of an immune attack on the hair follicle based on several lines of evidence.
Alopecia areata is associated with several concurrent diseases (comorbidities) including depression, anxiety, and several autoimmune diseases including thyroid disease (hyperthyroidism, hypothyroidism, goiter and thyroiditis), lupus erythematosus, vitiligo, psoriasis, rheumatoid arthritis and inflammatory bowel disease. The frequency of these concurrent diseases varies between geographically separate populations, which may suggest genetic variability within these different populations.
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The Alopecia Areata market report also covers emerging drugs, current treatment practices, Alopecia Areata market share of the individual therapies, current and forecasted Alopecia Areata Market Size from 2017 to 2030 segmented by seven major markets.
The report provides a detailed current Alopecia Areata treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.
Alopecia Areata Market Key Facts
As per the National Organization of Rare Disease, alopecia areata is most common among the children and approximately 2.5 million people are suffering from alopecia areata in the United States.
As per Herbert Pratt et al. 2017, alopecia areata affects approximately two percent of the general population at some point during their lifetime
Key Benefits of Alopecia Areata Market Report
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Alopecia Areata market report provides an in-depth analysis of Alopecia Areata Market Size, Share, Trend, Epidemiology and Market Forecast till 2030, in 7 major market i.e. EU5 (Germany, Italy, Spain, France and the UK), Japan, and the United States.
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The Alopecia Areata market report will help in developing business strategies by understanding the Alopecia Areata Market trends & developments, key players and future market competition that will shape and drive the Alopecia Areata market in the upcoming years.
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The Alopecia Areata market report covers Alopecia Areata current treatment practices, emerging drugs, market share of the individual therapies in 7 MM.
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The report provides a detailed assessment of the Alopecia Areata market in terms of market drivers & barriers, Unmet Needs, market opportunities, patient population, comparative analysis of pipeline products with detailed clinical profiles, and other factors.
Currently, there is no cure and no FDA-approved treatments for alopecia. The alopecia areata (AA) is the most common form of alopecia and is characterized by patchy scalp baldness. The potential for hair recovery is maintained but, at present, there is no treatment able to induce a permanent remission of this disease or approved to treat it. Thus, the market is completely dominated by off-label drug therapies.
Alopecia Areata market size is anticipated to Increase during the study period, 2017–2030. The key driver for the surge in market size is the rise in the number of Prevalent cases of Alopecia Areata patients in 7MM.
The Alopecia Areata market outlook section of the report helps to build the detailed comprehension of the historic, current and forecasted Alopecia Areata market trends by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand for better technology.
The report gives a thorough detail of Alopecia Areata market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, and view of the key opinion leaders.
Alopecia Areata Epidemiology
The Alopecia Areata epidemiology section covers insights about historical and current Alopecia Areata patient pool and forecasted trends for every seven major countries (i.e. the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and Japan from 2017 to 2030.
It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Alopecia Areata Drugs Uptake and Key Market Players
The Alopecia Areata Drugs Uptake section focuses on the rate of uptake of the potential drugs recently launched in the Alopecia Areata market or expected to get launched in the market during the study period. The analysis covers Alopecia Areata market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The dynamics of Alopecia Areata market is anticipated to change in the coming years owing to the improvement in the diagnosis methodologies, raising awareness of the diseases, incremental healthcare spending across the world, and also expects the launch of emerging therapies during the forecast period of 2020–2030.
Some of the key players involoved in developing therapies for Alopecia Areata includes:
Pfizer
Suzhou Zelgen Biopharmaceuticals
Eli Lilly and Company
Incyte Corporation
Legacy Healthcare
Concert Pharmaceuticals
Alcaris Therapeutics Inc.
And many others.
Drugs Covered
PF-06651600
Jaktinib
Baricitinib
ATI-502
LH-8
CTP-543
And many others.
Table of Content
1. Key Insights
2. Executive Summary
3. Alopecia Areata Competitive Intelligence Analysis
4. Alopecia Areata Market Overview at a Glance
5. Alopecia Areata Disease Background and Overview
6. Alopecia Areata Patient Journey
7. Alopecia Areata Epidemiology and Patient Population
8. Alopecia Areata Treatment Algorithm, Current Treatment, and Medical Practices
9. Alopecia Areata Unmet Needs
10. Key Endpoints of Alopecia Areata Treatment
11. Alopecia Areata Marketed Products
12. Alopecia Areata Emerging Therapies
13. Alopecia Areata Seven Major Market Analysis
14. Attribute Analysis
15. Alopecia Areata Market Outlook (7 major markets)
16. Alopecia Areata Access and Reimbursement Overview
17. KOL Views on the Alopecia Areata Market.
18. Alopecia Areata Market Drivers
19. Alopecia Areata Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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