Gastroesophageal reflux disease (GERD) is caused by the abnormal reflux of gastric contents into the esophagus. According to the presence of esophageal mucosal breaks; GERD can be divided into two groups, erosive esophagitis and nonerosive reflux disease (NERD).
The term “erosive esophagitis,” which denotes esophageal mucosal erosive changes, has several synonyms: recurrent, reflux, regurgitant, peptic and marginal esophagitis. The term “erosive esophagitis,” is used for it covers mucosal changes other than erosion or ulceration and occurs without reflux or peptic activity.
According to a study by Richter et al. (2018), “Patients with GERD with the typical reflux syndrome associated with erosive esophagitis and hiatal hernia can have mucosal eosinophilia, which often is confined to the distal esophagus. It is not clear what proportion of patients with GERD present with these features, but it is likely to be less than 10%.” In the same study, it was found that from 2003 to 2006, there were approximately 10,570 hospital admissions annually for erosive esophagitis.
Acid suppression with H2 receptor antagonists (H2RAs) and proton pump inhibitors (PPIs) are a standard treatment for gastroesophageal reflux disease and erosive esophagitis in adults and increasingly is becoming first-line therapy for children aged 1–17 years.
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The Erosive Esophagitis (EE) market report also covers emerging drugs, current treatment practices, Erosive Esophagitis (EE) market share of the individual therapies, current and forecasted Erosive Esophagitis (EE) Market Size from 2017 to 2030 segmented by seven major markets.
The report provides a detailed current Erosive Esophagitis (EE) treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.
Erosive Esophagitis (EE) Market Key Facts
According to a study by Joel E. Richter et al., (2018), in the US, estimates of the prevalence of GERD symptoms have ranged from 6% to 30%, with heterogeneity related to the particular questionnaire used, including the threshold frequency and duration of symptoms required to be classified as GERD. The prevalence of at least weekly GERD symptoms in the US is approximately 20%.
As per results of a study by Kusakari M. et al, (2020), the proportion with erosive esophagitis or endoscopic Barrett’s esophagus increased significantly compared between 2005-2012 and 2013-2019 time period (9.8% to 18.1% for GERD, and 2.5% to 9.6 % for Barrett’s).
In persons with GERD symptoms, about 20% are found to have erosive esophagitis, while ulcers or strictures are found in less than 5% of all patients with erosive esophagitis.
Up to 90% of patients with Erosive Esophagitis (EE) may experience symptomatic relapse within six months of stopping treatment.
Key Benefits of Erosive Esophagitis (EE) Market Report
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Erosive Esophagitis (EE) market report provides an in-depth analysis of Erosive Esophagitis (EE) Market Size, Share, Trend, Epidemiology and Market Forecast till 2030, in 7 major market i.e. EU5 (Germany, Italy, Spain, France and the UK), Japan, and the United States.
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The Erosive Esophagitis (EE) market report will help in developing business strategies by understanding the Erosive Esophagitis (EE) Market trends & developments, key players and future market competition that will shape and drive the Erosive Esophagitis (EE) market in the upcoming years.
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The Erosive Esophagitis (EE) market report covers Erosive Esophagitis (EE) current treatment practices, emerging drugs, market share of the individual therapies in 7 MM.
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The report provides a detailed assessment of the Erosive Esophagitis (EE) market in terms of market drivers & barriers, Unmet Needs, market opportunities, patient population, comparative analysis of pipeline products with detailed clinical profiles, and other factors.
Erosive Esophagitis (EE) Market
Erosive Esophagitis (EE) market size is expected to increase during the forecast period owing to the increasing prevalent population of Erosive Esophagitis in the seven major markets.
The Erosive Esophagitis (EE) market outlook section of the report helps to build the detailed comprehension of the historic, current and forecasted Erosive Esophagitis (EE) market trends by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand for better technology.
The report gives a thorough detail of Erosive Esophagitis (EE) market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, and view of the key opinion leaders.
Erosive Esophagitis (EE) Epidemiology
The Erosive Esophagitis (EE) epidemiology section covers insights about historical and current Erosive Esophagitis (EE) patient pool and forecasted trends for every seven major countries (i.e. the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and Japan from 2017 to 2030.
It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Erosive Esophagitis (EE) Drugs Uptake and Key Market Players
The Erosive Esophagitis (EE) Drugs Uptake section focuses on the rate of uptake of the potential drugs recently launched in the Erosive Esophagitis (EE) market or expected to get launched in the market during the study period. The analysis covers Erosive Esophagitis (EE) market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The dynamics of the Erosive Esophagitis market is anticipated to change in the coming years owing to the approval of the upcoming therapy.
The key companies in the Erosive Esophagitis (EE) market include:
Takeda
Ironwood Pharma
Daewoong Pharmaceutical
Luoxin Pharmaceutical
And many others
Erosive Esophagitis (EE) therapies covered in the report include:
DWP 14012
LXI-15028
Vonoprazan
YYD601
IW-3718
And many more
Table of Content
1. Key Insights
2. Executive Summary
3. Erosive Esophagitis (EE) Competitive Intelligence Analysis
4. Erosive Esophagitis (EE) Market Overview at a Glance
5. Erosive Esophagitis (EE) Disease Background and Overview
6. Erosive Esophagitis (EE) Patient Journey
7. Erosive Esophagitis (EE) Epidemiology and Patient Population
8. Erosive Esophagitis (EE) Treatment Algorithm, Current Treatment, and Medical Practices
9. Erosive Esophagitis (EE) Unmet Needs
10. Key Endpoints of Erosive Esophagitis (EE) Treatment
11. Erosive Esophagitis (EE) Marketed Products
12. Erosive Esophagitis (EE) Emerging Therapies
13. Erosive Esophagitis (EE) Seven Major Market Analysis
14. Attribute Analysis
15. Erosive Esophagitis (EE) Market Outlook (7 major markets)
16. Erosive Esophagitis (EE) Access and Reimbursement Overview
17. KOL Views on the Erosive Esophagitis (EE) Market.
18. Erosive Esophagitis (EE) Market Drivers
19. Erosive Esophagitis (EE) Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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