Breast cancer is a disease in which cells in the breast grow out of control. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Most breast cancers express the estrogen receptor (ER) receptor and are negative for the human epidermal growth factor receptor 2 (HER2) receptor. The backbone of their systemic therapy consists of hormonal therapies that block the function of ER through various mechanisms. These include blockade of the receptor itself in breast cancer cells, blockade of the production of its major ligand, estradiol, or degradation of the receptor. However, a subset of ER+/HER2− breast cancers, mostly corresponding to the genomic luminal B genotype, are resistant to hormonal manipulations from the outset of therapies.
DelveInsight’s, “ER+/ HER2-ve Breast Cancer Pipeline Insight, 2021” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in ER+/ HER2 -ve Breast Cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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ER+/ HER2-ve Breast Cancer Key Players:
- Eisai
- G1 Therapeutics
- Genetech/La Roche
- Sanofi
- AstraZeneca
- And Many Others
DelveInsight’s ER+/ HER2-ve Breast Cancer report covers around 5+ products under different phases of clinical development like:
- Late-stage products (Phase III)
- Mid-stage products (Phase II and Phase I/II)
- Early-stage products (Phase I/II and Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
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ER+/ HER2-ve Breast Cancer Therapies:
- H3B-6545
- G1T48
- GDC-9545
- SAR439859
- AZD9833
- And Many Others
Current ER+/ HER2-ve Breast Cancer Treatment Scenario and ER+/ HER2-ve Breast Cancer Emerging Therapies:
- How many companies are developing ER+/ HER2 -ve Breast Cancer drugs?
- How many ER+/ HER2 -ve Breast Cancer drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of ER+/ HER2 -ve Breast Cancer?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the ER+/ HER2 -ve Breast Cancer therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for ER+/ HER2 -ve Breast Cancer and their status?
- What are the key designations that have been granted to the emerging drugs?
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Table of Contents:
Introduction
Executive Summary
ER+/ HER2 -ve Breast Cancer: Overview
Pipeline Therapeutics
• Comparative Analysis
Therapeutic Assessment
ER+/ HER2 -ve Breast Cancer – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
ER+/ HER2 -ve Breast Cancer Collaboration Deals
Late Stage Products (Phase III)
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
• Comparative Analysis
Rintodestrant (G1T48): G1 Therapeutics
Drug profiles in the detailed report…..
Pre-clinical and Discovery Stage Products
Drug profiles in the detailed report…..
Inactive Products
• Comparative Analysis
ER+/ HER2 -ve Breast Cancer Key Companies
ER+/ HER2 -ve Breast Cancer Key Products
ER+/ HER2 -ve Breast Cancer- Unmet Needs
ER+/ HER2 -ve Breast Cancer- Market Drivers and Barriers
ER+/ HER2 -ve Breast Cancer- Future Perspectives and Conclusion
ER+/ HER2 -ve Breast Cancer Analyst Views
ER+/ HER2 -ve Breast Cancer Key Companies
Appendix
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