Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare entity grouped with the acute myeloid leukemia-related precursor neoplasms in the 2008 World Health Organization classification. It is a clinically aggressive tumor that often initially presents as cutaneous lesions and subsequently progresses to bone marrow involvement and leukemic dissemination characterized by enhanced expression of CD56, CD4, and CD123.
DelveInsight’s “Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Market Insights, Epidemiology, and Market Forecast-2030” report delivers an in-depth understanding of the Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN), historical and forecasted epidemiology as well as the Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Some key facts of Blastic Plasmacytoid Dendritic Cell Neoplasm Market are:
- The total incident population of BPDCN in 7MM countries was estimated to be 1,786 cases in 2017.
- The market size of BPDCN in the seven major markets was found to be USD 17.79 million in 2017.
- 90% of patients with BPDCN present with asymptomatic skin lesions – and early recognition can be challenging due to overlapping features with other benign and malignant disorders
- More men than women are diagnosed with BPDCN (~3:1 ratio), and it is most common in patients age 60 years and older.
- Drugs in the clinical trials are expected to propel the growth of the of Blastic Plasmacytoid Dendritic Cell Neoplasm drugs market in the upcoming years
- Expected launch of UCART123 (Cellectis), IMGN632 (ImmunoGen), XmAb14045 (Xencor) etc. shall fuel the growth of the market during the forecast period i.e., 2020-2030.
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BPDCN can be referred by different names such as blastic NK cell lymphoma, agranular CD4+ NK cell leukemia, blastic NK leukemia/lymphoma, and agranular CD4+ CD56+ hematodermic neoplasm. Also, as per WHO 2016 classification, BPDCN is currently classified as a distinct entity within the myeloid neoplasm and acute leukemia classification.
Common BPDCN symptoms include:
- Deep purple skin lesions.
- Fatigue.
- Fever.
- Night sweats.
Some of the BPCDN Companies are:
- Immunogen
- Cellectis
- Xencor
- MustangBio
- And Many Others
Some of the Blastic Plasmacytoid Dendritic Cell Neoplasm Therapies are:
- IMGN632
- UCART123
- MB 102
- XmAb14045
- And Many Others
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Table of Contents:
1. Key Insights
2. Executive summary
3. Organizations
4. Epidemiology and Market Methodology
5. Blastic plasmacytoid dendritic cell neoplasm (BPDCN): Market Overview at a Glance
6. Blastic plasmacytoid dendritic cell neoplasm (BPDCN): Disease Overview
7. Epidemiology and Patient Population
8. Current Treatment Practices
9. Unmet Needs
10. Marketed drugs
11. Elzonris: Stemline Therapeutics
12. Emerging Therapies
13. Key Cross Competition
14. MB-102: Mustang Bio
15. IMGN632: ImmunoGen/ Jazz Pharmaceuticals
16. UniCAR02-T-CD123: Cellex Patient Treatment GmbH
17. Venetoclax: AbbVie
18. XmAb14045: Xencor
19. Blastic plasmacytoid dendritic cell neoplasm (BPDCN): 7 Major Market Analysis
20. Seven Major Market Outlook
21. Total market size of Blastic plasmacytoid dendritic cell neoplasm in Japan
22. Total market size of Blastic plasmacytoid dendritic cell neoplasm by by Line of Therapies in Japan
23. Market Drivers
24. Market Barriers
25. SWOT Analysis
26. Reimbursement policies
27. Case Study
28. KOL Views
29. Appendix
30. Report Methodology
31. DelveInsight Capabilities
32. Disclaimer
33. About DelveInsight
34. Bibliography
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