The Aortic Stenosis market report covers emerging drugs, current treatment practices, market share of the individual therapies, current and forecasted market size from 2017 to 2030. It evaluates the current treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
Aortic Stenosis: An Overview
Aortic stenosis is the obstruction of blood flow across the aortic valve. Among symptomatic patients with medically treated moderate-to-severe aortic stenosis, mortality from the onset of symptoms is approximately 25% at 1 year and 50% at 2 years. Symptoms of aortic stenosis usually develop gradually after an asymptomatic latent period of 10-20 Years.
Aortic Stenosis Market Key Facts
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Aortic stenosis is the second most common valvular lesion in the United States. It is present in about 5% of the population at age 65 with an increasing prevalence with advancing age. A meta-analysis of predominantly older studies conducted in Europe, the USA, and Taiwan found a population prevalence of AS of 12.4%, and a prevalence of 3.4% of severe AS in those aged 75 years and older.
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As per a study by Pujari et al. (2021), the prevalence of calcific aortic stenosis is about 1% to 2% in patients aged 65 or more, 12% in patients aged 65 or more, and about 3.4% of patients aged greater than 75 have severe aortic stenosis. The prevalence of aortic sclerosis ranges from 9-45% in patients with a mean age of 54 to 81 and increases with age.
Aortic Stenosis Market
Aortic Stenosis therapeutics size is expected to increase during the forecast period owing to the extensive research and development activities of pharmaceutical companies and the expected launch of approved therapies.
The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Aortic Stenosis market size and share by analyzing the impact of current therapies on the market, unmet needs, drivers, and barriers, and demand for better technology.
The report gives a thorough detail of the Aortic Stenosis market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.
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Aortic Stenosis Epidemiology
The epidemiology section covers insights about the historical and current Aortic Stenosis patient pool and forecasted trends for every seven major countries from 2017 to 2030. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Aortic Stenosis Epidemiology Segmentation
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Gender- specific cases of Aortic Stenosis (AS)
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Age- specific cases of Aortic Stenosis (AS)
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Prevalent cases of Aortic Stenosis (AS)
Aortic Stenosis Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Aortic Stenosis market or expected to get launched in the market during the study period. The analysis covers the Aortic Stenosis market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The report also covers the Aortic Stenosis Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses the recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies.
Aortic Stenosis Therapeutics Analysis
Some of the key companies in the Aortic Stenosis Market include:
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MyoKardia
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Medtronics
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Edwards Lifesciences
And many others
Aortic Stenosis Therapies covered in the report include:
Mavacamten – Mavacamten is the first therapeutic candidate in a new class of direct myosin inhibitors that targets excessive contractility and impaired relaxation, myocardial energetics, and compliance, with the intent of correcting the abnormal function of the hypertrophic cardiomyopathy (HCM) heart.
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Table of Content
1. Key Insights
2. Executive Summary
3. Aortic Stenosis Competitive Intelligence Analysis
4. Aortic Stenosis Market Overview at a Glance
5. Aortic Stenosis Disease Background and Overview
6. Aortic Stenosis Patient Journey
7. Aortic Stenosis Epidemiology and Patient Population
8. Aortic Stenosis Treatment Algorithm, Current Treatment, and Medical Practices
9. Aortic Stenosis Unmet Needs
10. Key Endpoints of Aortic Stenosis Treatment
11. Aortic Stenosis Marketed Products
12. Aortic Stenosis Emerging Therapies
13. Aortic Stenosis Seven Major Market Analysis
14. Attribute Analysis
15. Aortic Stenosis Market Outlook (7 major markets)
16. Aortic Stenosis Access and Reimbursement Overview
17. KOL Views on the Aortic Stenosis Market.
18. Aortic Stenosis Market Drivers
19. Aortic Stenosis Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The table of contents is not exhaustive; the final content may vary.
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