The Sepsis market report covers emerging drugs, current treatment practices, market share of the individual therapies, current and forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
Sepsis: An Overview
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis can be the clinical manifestation of infections acquired both in the community setting and in health care facilities.
Anyone affected by an infection, severe injury, or serious non-communicable disease can progress to Sepsis, but vulnerable populations are at higher risk, including older persons, pregnant or recently pregnant women, neonates, hospitalized patients, patients in intensive care units, etc.
The initial evaluation of a patient with Sepsis includes medical history, physical examination, and clinical symptoms, along with the detection of some biomarkers (such as C reactive protein and procalcitonin), which are crucial elements for early diagnosis of Sepsis and the timely establishment of its appropriate clinical management.
Sepsis Market Key Facts
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In 2020, the total cases of sepsis were estimated to be 3,400,940 in the 7MM.
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Assessments indicate that 57% of all cases were sepsis without organ dysfunction followed by septic shock (24.63%) and severe sepsis (18.37%) in the United States in 2018.
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Among the 7MM, males are affected more as compared to females (except in the US)
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Out of EU5 countries, Germany had the highest incident cases in 2020 followed by the UK and Spain. France accounted for the least number of cases in 2020.
The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Sepsis market size by analyzing the impact of current and emerging therapies in the market. It also provides a detailed assessment of the market drivers & barriers, unmet needs, and emerging technologies.
The report gives a thorough detail of the Sepsis market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MoA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.
Sepsis Epidemiology
The epidemiology section covers insights about the historical and current Sepsis patient pool and forecasted trends for every seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Sepsis Epidemiology Segmentation
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Total Incident Cases of Sepsis
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Gender-specific Incident Cases of Sepsis
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Severity-specific Incident Cases of Sepsis
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Origin-specific Incident Cases of Sepsis
Sepsis Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Sepsis market or expected to get launched in the market during the study period. The analysis covers Sepsis market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The report also covers the Sepsis Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses the recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies.
Sepsis Therapeutics Analysis
The approved drugs for sepsis are not very much, and in the emerging pipeline, it was seen that many drugs in the pipeline failed to show any improvement in the clinical trial. The main reason for the failure of the trials was the selection for the primary endpoint, but in new trials, the primary endpoint was to determine the change observed at the 28-day all-cause mortality rate compared to the placebo control group.
At present several companies are involved in the therapeutics development for the Sepsis that are expected to launch in the coming years.
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Key Companies in the Sepsis Market include:
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Inotrem
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Shionogi
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Revimmune
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AM-Pharma
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Adrenomed
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Vivacelle Bio
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ABIONYX Pharma
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Enlivex Therapeutics
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Par Pharmaceutical
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Ono Pharmaceutical
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La Jolla Pharmaceuticals
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BioMarck Pharmaceuticals
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Baxter Healthcare Corporation
And many more.
Sepsis Therapies covered in the report include:
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BIO-11006
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CER-001
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CYT107
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VBI-S
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Allocetra:
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Adrecizumab
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Nangibotide (LR12)
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Fetroja/Fetcroja (Cefiderocol)
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Recombinant human alkaline phosphatase
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Esmolol (esmolol hydrochloride)
And many more.
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Table of Content
1. Key Insights
2. Executive Summary
3. Sepsis Competitive Intelligence Analysis
4. Sepsis Market Overview at a Glance
5. Sepsis Disease Background and Overview
6. Sepsis Patient Journey
7. Sepsis Epidemiology and Patient Population
8. Sepsis Treatment Algorithm, Current Treatment, and Medical Practices
9. Sepsis Unmet Needs
10. Key Endpoints of Sepsis Treatment
11. Sepsis Marketed Products
12. Sepsis Emerging Therapies
13. Sepsis Seven Major Market Analysis
14. Attribute Analysis
15. Sepsis Market Outlook (7 major markets)
16. Sepsis Access and Reimbursement Overview
17. KOL Views on the Sepsis Market.
18. Sepsis Market Drivers
19. Sepsis Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The table of contents is not exhaustive; the final content may vary.
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