Bone Metastasis Overview

When cancer cells from other parts of the body travel to the bone, this is known as bone metastasis. The spine is where bone metastases occurs most frequently. Bone pain is one of the first signs that someone may experience.

“Bone Metastasis Pipeline Insight, 2023“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Bone Metastasis Market.

The Bone Metastasis Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the Bone Metastasis Pipeline Report:

• Companies across the globe are diligently working toward developing novel Bone Metastasis treatment therapies with a considerable amount of success over the years. Bone Metastasis Key players such as – BiologicsMD, Shanghai JMT-Bio Inc., AlaMab Therapeutics, Exelixis, Mabwell (Shanghai) Bioscience Co., Ltd., Qilu Pharmaceutical Co., Ltd., and others, are developing therapies for the Bone Metastasis treatment 

• Bone Metastasis Emerging therapies such as – BMD 3151, JMT103, ALMB-0168, Cabozantinib, MW032, QL1206, and others are expected to have a significant impact on the Bone Metastasis market in the coming years.   
• MW032 is a Denosumab biosimilar being developed by Mabwell (Shanghai) Bioscience Co., Ltd. Denosumab is a fully human monoclonal antibody that binds the cytokine RANKL (receptor activator of NFκB ligand), an essential factor initiating bone turnover.

Bone Metastasis Pipeline Therapeutics Assessment

• Bone Metastasis Assessment by Product Type
• Bone Metastasis By Stage and Product Type
• Bone Metastasis Assessment by Route of Administration
• Bone Metastasis By Stage and Route of Administration
• Bone Metastasis Assessment by Molecule Type
• Bone Metastasis by Stage and Molecule Type

DelveInsight’s Bone Metastasis Report covers around 10+ products under different phases of clinical development like

• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Emerging Bone Metastasis Drugs Under Different Phases of Clinical Development Include:

• BMD 3151: BiologicsMD
• JMT103: Shanghai JMT-Bio Inc.
• ALMB-0168: AlaMab Therapeutics
• Cabozantinib: Exelixis
• MW032: Mabwell (Shanghai) Bioscience Co., Ltd.
• QL1206: Qilu Pharmaceutical Co., Ltd.

Bone Metastases Emerging Drugs

MW032: Mabwell (Shanghai) Bioscience Co., Ltd.

Mabwell (Shanghai) Bioscience Co., Ltd. is creating MW032, a biosimilar to Denosumab. A fully human monoclonal antibody called denosumab binds to the cytokine RANKL (receptor activator of NF-B ligand), which is crucial for starting the process of bone turnover. By preventing osteoclast formation, function, and survival, RANKL inhibition lowers bone resorption. The development of MW032 for the treatment of Bone Metastases from Solid Tumors is currently in Phase III.

ALMB-0168: AlaMab Therapeutics

The humanised monoclonal antibody agonist ALMB-0168 is the first of its kind targeting the hemichannel Cx43 membrane protein. In pre-clinical in vitro and in vivo animal investigations, ALMB-0168 has proven to successfully inhibit osteosarcoma and bone metastasis by activating the Cx43 protein to release tumor-inhibiting cytokines. The FDA has granted ALMB-0168 classifications as an orphan drug and a rare paediatric disease for treatment in osteosarcoma.

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Bone Metastasis Pipeline Analysis:

The Bone Metastasis pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the Bone Metastasis treatment with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Bone Metastasis Treatment.
• Bone Metastasis key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Bone Metastasis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Bone Metastasis market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Further Bone Metastasis product details are provided in the report. Download the Bone Metastasis pipeline report to learn more about the emerging Bone Metastasis therapies

Bone Metastasis Pipeline Market Drivers

• Rise in the number of cases of cancers worldwide
• Development of promising circulating and tissue biomarkers

Bone Metastasis Pipeline Market Barriers

• Lack of healthcare services in low-income countries
• Lack of an effective multidisciplinary approach for treatment

Scope of Bone Metastasis Pipeline Drug Insight    

• Coverage: Global
• Key Bone Metastasis Companies: BiologicsMD, Shanghai JMT-Bio Inc., AlaMab Therapeutics, Exelixis, Mabwell (Shanghai) Bioscience Co., Ltd., Qilu Pharmaceutical Co., Ltd., and others
• Key Bone Metastasis Therapies: BMD 3151, JMT103, ALMB-0168, Cabozantinib, MW032, QL1206, and others
• Bone Metastasis Therapeutic Assessment: Bone Metastasis current marketed and Bone Metastasis emerging therapies
• Bone Metastasis Market Dynamics: Bone Metastasis market drivers and Bone Metastasis market barriers 

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Table of Contents

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