(Albany, USA) DelveInsight’s “Myelodysplastic Syndrome Market Insights, Epidemiology, and Market Forecast-2032” report delivers an in-depth understanding of Myelodysplastic Syndrome, historical and forecasted epidemiology as well as the Myelodysplastic Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.
The Myelodysplastic Syndrome market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Myelodysplastic Syndrome market size from 2019 to 2032, segmented by seven major markets. The Report also covers current Myelodysplastic Syndrome treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Myelodysplastic Syndrome market.
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Some facts of the Myelodysplastic Syndrome Market Report are:
- According to DelveInsight, Myelodysplastic Syndrome market size is expected to grow at a decent CAGR by 2032.
- Leading Myelodysplastic Syndrome companies working in the market are Novartis, Otsuka Holdings, Lupin, Medtronic, Agios Pharmaceuticals, Takeda Pharmaceutical, Onconova Therapeutics, Syros Pharmaceuticals, Helsinn Healthcare SA, Abbott, Boehringer Ingelheim International, Johnson & Johnson, MEI Pharma, Kind Pharmaceuticals, MTW Endoskopie Manufaktur, Aprea Therapeutics, Dr. Reddy’s Laboratories, AbbVie, Acceleron Pharma, Mylan N.V., Bristol-Myers Squibb, Eisai, LGM Pharma, Astex Pharmaceutical, Taiho Oncology, Fibrogen, Gilead Sciences, Pfizer, Geron Corporation, Karyopharm Therapeutics, Antengene Corporation, BerGenBio ASA, Jazz Pharmaceuticals, Sanofi, and others.
- Key Myelodysplastic Syndrome Therapies expected to launch in the market are Roxadustat, Venclexta (Venetoclax) + Azacitidine, Magrolimab ± Azacitidine, Sabatolimab + Azacitidine, SY-1425 + Azacitidine, Pevonedistat ± Azacitidine, Glasdegib + Azacitidine/Cytarabine, Imetelstat, Eltanexor (ATG 016; KPT-8602), Bemcentinib, Enasidenib, CPX-351, Eprenetapopt (APR-246), Fludarabine + Busulfan ± Clofarabine, Treosulfan ± fludarabine, others.
- The incident cases of Myelodysplastic Syndrome in Germany were estimated to be 4,515. While France, the UK, and Spain had 4,371, 3,302, and 2,010 cases respectively.
- On March 2024, Agios Pharmaceuticals announced results of a Phase 2a/2b, Open-label, Proof of Concept (Phase 2a) and Double-blind, Randomized, Placebo-Controlled (Phase 2b), Multicenter, Efficacy, and Safety Study of AG-946 in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes.
- On March 2024, Kind Pharmaceuticals announced results of a Phase 2, multicenter, randomized, open-lable study to evaluate the efficacy and safety of luspatercept (ACE-536) for the treatment of anemia due to lower risk Myelodysplastic syndromes (MDS)in patients subjects who are Red blood cell (RBC) non-transfusion dependent (NTD) and low transfusion burden (LTB).
- On March 2024, Syros Pharmaceuticals announced results of a Randomized, Double-blind, Placebo-controlled Phase 3 Study of Tamibarotene Plus Azacitidine Versus Placebo Plus Azacitidine in Newly Diagnosed, Adult Patients Selected for RARA-positive Higher-risk Myelodysplastic Syndrome (SELECT MDS-1).
- On March 2024, Novartis announced results of a Randomized, Double-blind, Placebo-controlled Phase II Multi-center Study of Intravenous MBG453 Added to Hypomethylating Agents in Adult Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R Criteria.
- On April 2024, Bristol-Myers Squibb announced results of a Phase 3b, Open-label Study Evaluating the Efficacy and Safety of Luspatercept (BMS-986346/ACE-536) Initiated at Maximum Approved Dose in LR-MDS With IPSS-R Very Low-, Low-, or Intermediate-risk Who Require RBC Transfusions (MAXILUS).
Myelodysplastic Syndrome Overview
Myelodysplastic syndrome (MDS) is a group of disorders characterized by abnormal production and development of blood cells in the bone marrow. It is also referred to as myelodysplasia. In a healthy individual, the bone marrow produces immature blood cells called stem cells, which then mature into red blood cells, white blood cells, and platelets. In Myelodysplastic syndrome, these stem cells do not mature properly, leading to the production of dysfunctional and immature blood cells known as blasts. These abnormal cells do not function properly and crowd out the healthy cells in the bone marrow, resulting in a decrease in the production of normal blood cells.
Myelodysplastic syndrome is typically diagnosed through a combination of blood tests, bone marrow aspiration, and biopsy. Treatment options for Myelodysplastic syndrome depend on several factors, including the patient’s age, overall health, and the risk of progression to acute myeloid leukemia (AML). Treatment may include supportive care measures such as blood transfusions or medications to manage symptoms, as well as more intensive therapies such as chemotherapy, targeted drug therapy, or stem cell transplantation.
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Myelodysplastic Syndrome Market
The Myelodysplastic Syndrome market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Myelodysplastic Syndrome market trends by analyzing the impact of current Myelodysplastic Syndrome therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.
This segment gives a thorough detail of the Myelodysplastic Syndrome market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Myelodysplastic Syndrome market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the Myelodysplastic Syndrome market in 7MM is expected to witness a major change in the study period 2019-2032.
Myelodysplastic Syndrome Epidemiology
The Myelodysplastic Syndrome epidemiology section provides insights into the historical and current Myelodysplastic Syndrome patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Myelodysplastic Syndrome market report also provides the diagnosed patient pool, trends, and assumptions.
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Myelodysplastic Syndrome Drugs Uptake
This section focuses on the uptake rate of the potential Myelodysplastic Syndrome drugs recently launched in the Myelodysplastic Syndrome market or expected to be launched in 2019-2032. The analysis covers the Myelodysplastic Syndrome market uptake by drugs, patient uptake by therapies, and sales of each drug.
Myelodysplastic Syndrome Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Myelodysplastic Syndrome market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Myelodysplastic Syndrome Pipeline Development Activities
The Myelodysplastic Syndrome report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Myelodysplastic Syndrome key players involved in developing targeted therapeutics.
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Myelodysplastic Syndrome Therapeutics Assessment
Major key companies are working proactively in the Myelodysplastic Syndrome Therapeutics market to develop novel therapies which will drive the Myelodysplastic Syndrome treatment markets in the upcoming years are Novartis, Otsuka Holdings, Lupin, Medtronic, Agios Pharmaceuticals, Takeda Pharmaceutical, Onconova Therapeutics, Syros Pharmaceuticals, Helsinn Healthcare SA, Abbott, Boehringer Ingelheim International, Johnson & Johnson, MEI Pharma, Kind Pharmaceuticals, MTW Endoskopie Manufaktur, Aprea Therapeutics, Dr. Reddy’s Laboratories, AbbVie, Acceleron Pharma, Mylan N.V., Bristol-Myers Squibb, Eisai, LGM Pharma, Astex Pharmaceutical, Taiho Oncology, Fibrogen, Gilead Sciences, Pfizer, Geron Corporation, Karyopharm Therapeutics, Antengene Corporation, BerGenBio ASA, Jazz Pharmaceuticals, Sanofi, and others.
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Myelodysplastic Syndrome Report Key Insights
1. Myelodysplastic Syndrome Patient Population
2. Myelodysplastic Syndrome Market Size and Trends
3. Key Cross Competition in the Myelodysplastic Syndrome Market
4. Myelodysplastic Syndrome Market Dynamics (Key Drivers and Barriers)
5. Myelodysplastic Syndrome Market Opportunities
6. Myelodysplastic Syndrome Therapeutic Approaches
7. Myelodysplastic Syndrome Pipeline Analysis
8. Myelodysplastic Syndrome Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Myelodysplastic Syndrome Market
Table of Contents
1. Key Insights
2. Executive Summary
3. Myelodysplastic Syndrome Competitive Intelligence Analysis
4. Myelodysplastic Syndrome Market Overview at a Glance
5. Myelodysplastic Syndrome Disease Background and Overview
6. Myelodysplastic Syndrome Patient Journey
7. Myelodysplastic Syndrome Epidemiology and Patient Population
8. Myelodysplastic Syndrome Treatment Algorithm, Current Treatment, and Medical Practices
9. Myelodysplastic Syndrome Unmet Needs
10. Key Endpoints of Myelodysplastic Syndrome Treatment
11. Myelodysplastic Syndrome Marketed Products
12. Myelodysplastic Syndrome Emerging Therapies
13. Myelodysplastic Syndrome Seven Major Market Analysis
14. Attribute Analysis
15. Myelodysplastic Syndrome Market Outlook (7 major markets)
16. Myelodysplastic Syndrome Access and Reimbursement Overview
17. KOL Views on the Myelodysplastic Syndrome Market
18. Myelodysplastic Syndrome Market Drivers
19. Myelodysplastic Syndrome Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
About DelveInsight
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