Acute Myeloid Leukemia Pipeline Drugs Analysis Report, 2024: FDA Approvals, Clinical Trials, Therapies, MOA, ROA by DelveInsight | Novartis AG, Genmab AS, Sanofi, Teva Pharma, Pfizer, Roche

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Acute Myeloid Leukemia Pipeline Drugs Analysis Report, 2024: FDA Approvals, Clinical Trials, Therapies, MOA, ROA by DelveInsight | Novartis AG, Genmab AS, Sanofi, Teva Pharma, Pfizer, Roche
(Las Vegas, Nevada, United States) As per DelveInsight’s assessment, globally, Acute Myeloid Leukemia pipeline constitutes 110+ key companies continuously working towards developing 120+ Acute Myeloid Leukemia treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

The Acute Myeloid Leukemia Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

 

“Acute Myeloid Leukemia Pipeline Insight, 2024“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Acute Myeloid Leukemia Market.

 

Some of the key takeaways from the Acute Myeloid Leukemia Pipeline Report:

  • Companies across the globe are diligently working toward developing novel Acute Myeloid Leukemia treatment therapies with a considerable amount of success over the years. 

  • Acute Myeloid Leukemia companies working in the treatment market are SystImmune, Jasper Therapeutics, Chimerix, Akeso Biopharma Co., Ltd., Syros Pharmaceuticals, TC Biopharm, Stemline Therapeutics, Orca Bio, Gilead Sciences, GlycoMimetics, and others, are developing therapies for the Acute Myeloid Leukemia treatment 

  • Emerging Acute Myeloid Leukemia therapies in the different phases of clinical trials are- GNC 035, JSP 191, ONC201, AK117, Tamibarotene, TCB008, Elzonris, Orca T, Magrolimab+ azacitidine, Uproleselan, and others are expected to have a significant impact on the Acute Myeloid Leukemia market in the coming years.  

  • In May 2024, GlycoMimetics, a biotechnology company based in the United States, has unveiled the key findings from its Phase III clinical trial of uproleselan, an E-selectin antagonist developed for the treatment of relapsed/refractory acute myeloid leukemia (r/r AML). The randomized, double-blind, placebo-controlled trial evaluated uproleselan in combination with either mitoxantrone, etoposide, and cytarabine (MEC) or fludarabine, cytarabine, and idarubicin (FAI) chemotherapy regimens. Patients were administered either uproleselan or a placebo during one cycle of induction and up to three cycles of consolidation, if applicable.

  • In August 2023, Gilead Sciences revealed that the US Food and Drug Administration (FDA) has decided to temporarily halt the screening and enrollment of patients in US-based studies examining the treatment of acute myeloid leukemia (AML) using magrolimab. This partial clinical hold comes in the wake of the termination of a Phase III trial exploring the combination of the same drug with azacitidine in patients diagnosed with higher-risk myelodysplastic syndromes (MDS). Gilead opted to discontinue the study due to unsatisfactory efficacy outcomes, rather than safety issues.

 

Acute Myeloid Leukemia Overview

Acute Myeloid Leukemia (AML) is a type of cancer that affects the bone marrow and blood. It is characterized by the rapid growth of abnormal white blood cells, known as myeloblasts or leukemic blasts, which are immature cells that fail to mature into normal white blood cells. These abnormal cells accumulate in the bone marrow and interfere with the production of normal blood cells, including red blood cells, white blood cells, and platelets.

 

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Emerging Acute Myeloid Leukemia Drugs Under Different Phases of Clinical Development Include:

  • GNC 035: SystImmune

  • JSP 191: Jasper Therapeutics

  • ONC201: Chimerix

  • AK117: Akeso Biopharma Co., Ltd.

  • Tamibarotene: Syros Pharmaceuticals

  • TCB008: TC Biopharm

  • Elzonris: Stemline Therapeutics

  • Orca T: Orca Bio

  • Magrolimab+ azacitidine: Gilead Sciences

  • Uproleselan: GlycoMimetics

 

Acute Myeloid Leukemia Route of Administration

Acute Myeloid Leukemia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

  • Oral

  • Intravenous

  • Subcutaneous

  • Parenteral

  • Topical

 

Acute Myeloid Leukemia Molecule Type

Acute Myeloid Leukemia Products have been categorized under various Molecule types, such as

  • Recombinant fusion proteins

  • Small molecule

  • Monoclonal antibody

  • Peptide

  • Polymer

  • Gene therapy

 

Acute Myeloid Leukemia Pipeline Therapeutics Assessment

  • Acute Myeloid Leukemia Assessment by Product Type

  • Acute Myeloid Leukemia By Stage and Product Type

  • Acute Myeloid Leukemia Assessment by Route of Administration

  • Acute Myeloid Leukemia By Stage and Route of Administration

  • Acute Myeloid Leukemia Assessment by Molecule Type

  • Acute Myeloid Leukemia by Stage and Molecule Type

 

DelveInsight’s Acute Myeloid Leukemia Report covers around 120+ products under different phases of clinical development like

  • Late-stage products (Phase III)

  • Mid-stage products (Phase II)

  • Early-stage product (Phase I)

  • Pre-clinical and Discovery stage candidates

  • Discontinued & Inactive candidates

  • Route of Administration

 

Further Acute Myeloid Leukemia product details are provided in the report. Download the Acute Myeloid Leukemia pipeline report to learn more about the emerging Acute Myeloid Leukemia therapies

 

Some of the key companies in the Acute Myeloid Leukemia Therapeutics Market include:

Key companies developing therapies for Acute Myeloid Leukemia are – GlycoMimetics, BioSight, Merck Sharp & Dohme LLC, Kura Oncology, Senti Biosciences, Chimerix, Takeda, Apollo Therapeutics, Immune-Onc Therapeutics, AbbVie/Genentech, Altor BioScience Corporation, Merck & Co, Astex Pharmaceuticals, Karyopharm Therapeutics, Mesoblast, SELLAS Life Sciences Group, Molecular Partners, Kling Biotherapeutics, HitGen, Chordia Therapeutics Inc, Cullinan Therapeutics Inc, Aptose Biosciences Inc, Celgene, and others.

 

Acute Myeloid Leukemia Pipeline Analysis:

The Acute Myeloid Leukemia pipeline report provides insights into 

  • The report provides detailed insights about companies that are developing therapies for the treatment of Acute Myeloid Leukemia with aggregate therapies developed by each company for the same.

  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Acute Myeloid Leukemia Treatment.

  • Acute Myeloid Leukemia key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

  • Acute Myeloid Leukemia Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 

  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Acute Myeloid Leukemia market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

 

Download Sample PDF Report to know more about Acute Myeloid Leukemia drugs and therapies

 

Acute Myeloid Leukemia Pipeline Market Drivers

  • Rising incidence of Acute Myeloid Leukemia, advancements in pharmacology and molecular biology to promote drug development, rising geriatric population are some of the important factors that are fueling the Acute Myeloid Leukemia Market.

 

Acute Myeloid Leukemia Pipeline Market Barriers

  • However, high cost associated with the management of AML, side effects associated with the AML treatment and other factors are creating obstacles in the Acute Myeloid Leukemia Market growth.

 

Scope of Acute Myeloid Leukemia Pipeline Drug Insight    

  • Coverage: Global

  • Key Acute Myeloid Leukemia Companies: SystImmune, Jasper Therapeutics, Chimerix, Akeso Biopharma Co., Ltd., Syros Pharmaceuticals, TC Biopharm, Stemline Therapeutics, Orca Bio, Gilead Sciences, GlycoMimetics, and others

  • Key Acute Myeloid Leukemia Therapies: GNC 035, JSP 191, ONC201, AK117, Tamibarotene, TCB008, Elzonris, Orca T, Magrolimab+ azacitidine, Uproleselan, and others

  • Acute Myeloid Leukemia Therapeutic Assessment: Acute Myeloid Leukemia current marketed and Acute Myeloid Leukemia emerging therapies

  • Acute Myeloid Leukemia Market Dynamics: Acute Myeloid Leukemia market drivers and Acute Myeloid Leukemia market barriers 

 

Request for Sample PDF Report for Acute Myeloid Leukemia Pipeline Assessment and clinical trials

 

Table of Contents

1. Acute Myeloid Leukemia Report Introduction

2. Acute Myeloid Leukemia Executive Summary

3. Acute Myeloid Leukemia Overview

4. Acute Myeloid Leukemia- Analytical Perspective In-depth Commercial Assessment

5. Acute Myeloid Leukemia Pipeline Therapeutics

6. Acute Myeloid Leukemia Late Stage Products (Phase II/III)

7. Acute Myeloid Leukemia Mid Stage Products (Phase II)

8. Acute Myeloid Leukemia Early Stage Products (Phase I)

9. Acute Myeloid Leukemia Preclinical Stage Products

10. Acute Myeloid Leukemia Therapeutics Assessment

11. Acute Myeloid Leukemia Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. Acute Myeloid Leukemia Key Companies

14. Acute Myeloid Leukemia Key Products

15. Acute Myeloid Leukemia Unmet Needs

16 . Acute Myeloid Leukemia Market Drivers and Barriers

17. Acute Myeloid Leukemia Future Perspectives and Conclusion

18. Acute Myeloid Leukemia Analyst Views

19. Appendix

20. About DelveInsight

 

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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