As per DelveInsight’s assessment, globally, Non-Hodgkin’s Lymphoma pipeline constitutes 200+ key companies continuously working towards developing 220+ Non-Hodgkin’s Lymphoma treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.
“Non-Hodgkin’s Lymphoma Pipeline Insight, 2024″ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Non-Hodgkin’s Lymphoma Market.
The Non-Hodgkin’s Lymphoma Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.
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Some of the key takeaways from the Non-Hodgkin’s Lymphoma Pipeline Report:
- Non-Hodgkin’s Lymphoma Companies across the globe are diligently working toward developing novel Non-Hodgkin’s Lymphoma treatment therapies with a considerable amount of success over the years.
- Non-Hodgkin’s Lymphoma companies working in the treatment market are Bio-thera solutions, Mustang Bio, Roche, Scopus Biopharma, Rafael Pharmaceuticals, AbbVie, Janssen, TG Therapeutics, Tessa Therapeutics, Epizyme, MEI Pharma, Loxo Oncology, Debiopharm, Eli Lilly, Angiocrine Bioscience, Autous, Genetech, Allogene Therapeutics, CarsGen Therapeutics, ADC Therapeutics, Nektar Therapeutics, HUTCHMED, Nanjing Yoko Biomedical, Bristol Myers Squibb, AI therapeutics, and others are developing therapies for the Non-Hodgkin’s Lymphoma treatment.
- Emerging Non-Hodgkin’s Lymphoma therapies in the different phases of clinical trials are HMPL-523, Devimistat, LAM-002, Abemaciclib, AUTO4, CNCT19, CAR-CD19 T Cells, CC-99282, Ibrutinib, Venetoclax, LOXO-305, Obinutuzumab, NKTR-255, Naratuximab emtansine, Loncastuximab tesirine, GB226, TT11, CPI 818, BI-1206, AB-205, and others are expected to have a significant impact on the Non-Hodgkin’s Lymphoma market in the coming years.
- In a phase II clinical trial for patients with refractory/relapsed (R/R) large B cell lymphoma (LBCL), obinutuzumab was administered prior to Glofit monotherapy to reduce tumor load.
- The latest update showed a complete response (CR) rate of 38% and an overall response rate (ORR) of 59% with a median follow-up of 20.1 months.
Non-Hodgkin’s Lymphoma Overview
Non-Hodgkin’s lymphoma (NHL) is a diverse group of blood cancers that originate in the lymphatic system, which is a critical part of the body’s immune system. Unlike Hodgkin’s lymphoma, NHL is characterized by the absence of Reed-Sternberg cells. NHL includes various subtypes, classified based on the type of lymphocyte involved (B-cells or T-cells) and their growth patterns (indolent or aggressive).
Non-Hodgkin’s lymphoma can occur at any age but is more common in older adults. Risk factors include weakened immune systems, autoimmune diseases, certain infections (like HIV and Epstein-Barr virus), and exposure to chemicals like pesticides. Symptoms often include swollen lymph nodes, fever, night sweats, weight loss, and fatigue.
Non-Hodgkin’s lymphoma Diagnosis involves a combination of physical examinations, blood tests, imaging studies, and biopsies to determine the specific type and stage of the lymphoma. Treatment strategies depend on the subtype, stage, and overall health of the patient. Common treatments include chemotherapy, radiation therapy, targeted therapies, immunotherapy, and stem cell transplants.
Advancements in understanding the molecular and genetic basis of Non-Hodgkin’s lymphoma have led to the development of targeted treatments that improve outcomes and reduce side effects. Ongoing research focuses on novel therapies and personalized medicine approaches to enhance treatment efficacy and patient quality of life.
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Emerging Non-Hodgkin’s Lymphoma Drugs Under Different Phases of Clinical Development Include:
- Venetoclax: AbbVie
- Ibrutinib: Janssen
- Naratuximab emtansine: Debiopharm
- NKTR-255: Nektar Therapeutics
- LOXO-305: Loxo Oncology
- LAM–002: AI Therapeutics
- CNCT19: Juventas Cell Therapy Ltd.
- GB226: Genor Biopharma
- BI-1206: BioInvent International
- CAR-CD19 T Cells: Carsgen therapeutics
- AUTO4: Autolus
- TT11: Tessa Therapeutics
- CC-99282: Celgene
- AB-205: Angiocrine Bioscience
Route of Administration
Non-Hodgkin’s Lymphoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
- Subcutaneous
- Intravenous
- Oral
- Injectable
Molecule Type
Non-Hodgkin’s Lymphoma Products have been categorized under various Molecule types, such as
- Small molecules
- Monoclonal antibodies
Non-Hodgkin’s Lymphoma Pipeline Therapeutics Assessment
- Non-Hodgkin’s Lymphoma Assessment by Product Type
- Non-Hodgkin’s Lymphoma By Stage and Product Type
- Non-Hodgkin’s Lymphoma Assessment by Route of Administration
- Non-Hodgkin’s Lymphoma By Stage and Route of Administration
- Non-Hodgkin’s Lymphoma Assessment by Molecule Type
- Non-Hodgkin’s Lymphoma by Stage and Molecule Type
DelveInsight’s Non-Hodgkin’s Lymphoma Pipeline Report covers around 150+ products under different phases of clinical development like
- Late-stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I)
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
Further Non-Hodgkin’s Lymphoma product details are provided in the report. Download the Non-Hodgkin’s Lymphoma pipeline report to learn more about the emerging Non-Hodgkin’s Lymphoma therapies @ Non-Hodgkin’s Lymphoma pipeline analysis
Some of the key companies in the Non-Hodgkin’s Lymphoma Therapeutics Market include:
Key Non-Hodgkin’s Lymphoma companies developing therapies are Bio-thera solutions, Mustang Bio, Roche, Scopus Biopharma, Rafael Pharmaceuticals, AbbVie, Janssen, TG Therapeutics, Tessa Therapeutics, Epizyme, MEI Pharma, Loxo Oncology, Debiopharm, Eli Lilly, Angiocrine Bioscience, Autous, Genetech, Allogene Therapeutics, CarsGen Therapeutics, ADC Therapeutics, Nektar Therapeutics, HUTCHMED, Nanjing Yoko Biomedical, Bristol Myers Squibb, AI therapeutics, and others.
Non-Hodgkin’s Lymphoma Pipeline Analysis:
The Non-Hodgkin’s Lymphoma pipeline report provides insights into
- The report provides detailed insights about companies that are developing therapies for the treatment of Non-Hodgkin’s Lymphoma with aggregate therapies developed by each company for the same.
- It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Non-Hodgkin’s Lymphoma Treatment.
- Non-Hodgkin’s Lymphoma key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
- Non-Hodgkin’s Lymphoma Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
- Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Non-Hodgkin’s Lymphoma market.
The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
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Non-Hodgkin’s Lymphoma Pipeline Market Drivers
Several drivers contribute to the growth of the Non-Hodgkin’s Lymphoma (NHL) pipeline market. Firstly, there is a continuous demand for improved treatment options for NHL patients, particularly for those with relapsed or refractory disease. This drives research and development efforts to discover novel therapies and advance existing treatments. Secondly, the increasing understanding of the molecular and genetic mechanisms underlying NHL has led to the development of targeted therapies that specifically address the unique characteristics of individual NHL subtypes. Thirdly, advancements in technology and diagnostic tools enable better patient stratification and identification of appropriate candidates for specific treatments. Lastly, favorable regulatory environments and expedited approval pathways for breakthrough therapies facilitate the entry of innovative treatments into the market.
Non-Hodgkin’s Lymphoma Pipeline Market Barriers
One of the barriers in the Non-Hodgkin’s lymphoma (NHL) pipeline market is the complex and heterogeneous nature of NHL itself. NHL comprises various subtypes with distinct molecular characteristics, making it challenging to develop targeted therapies that effectively address each subtype. Additionally, the limited understanding of the underlying mechanisms and genetic drivers of NHL subtypes hinders the identification and development of novel therapeutic targets. Regulatory hurdles and the high costs associated with clinical trials and drug development pose additional barriers, potentially limiting the number of experimental treatments progressing through the pipeline. Moreover, the competitive landscape and the availability of established treatment options may impact the willingness of pharmaceutical companies to invest in NHL research and development.
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Scope of Non-Hodgkin’s Lymphoma Pipeline Drug Insight
- Coverage: Global
- Key Non-Hodgkin’s Lymphoma Companies: Bio-thera solutions, Mustang Bio, Roche, Scopus Biopharma, Rafael Pharmaceuticals, AbbVie, Janssen, TG Therapeutics, Tessa Therapeutics, Epizyme, MEI Pharma, Loxo Oncology, Debiopharm, Eli Lilly, Angiocrine Bioscience, Autous, Genetech, Allogene Therapeutics, CarsGen Therapeutics, ADC Therapeutics, Nektar Therapeutics, HUTCHMED, Nanjing Yoko Biomedical, Bristol Myers Squibb, AI therapeutics, and others.
- Key Non-Hodgkin’s Lymphoma Therapies: HMPL-523, Devimistat, LAM-002, Abemaciclib, AUTO4, CNCT19, CAR-CD19 T Cells, CC-99282, Ibrutinib, Venetoclax, LOXO-305, Obinutuzumab, NKTR-255, Naratuximab emtansine, Loncastuximab tesirine, GB226, TT11, CPI 818, BI-1206, AB-205, and others.
- Non-Hodgkin’s Lymphoma Therapeutic Assessment: Non-Hodgkin’s Lymphoma current marketed and Non-Hodgkin’s Lymphoma emerging therapies
- Non-Hodgkin’s Lymphoma Market Dynamics: Non-Hodgkin’s Lymphoma market drivers and Non-Hodgkin’s Lymphoma market barriers
Table of Contents
- Non-Hodgkin’s Lymphoma Report Introduction
- Non-Hodgkin’s Lymphoma Executive Summary
- Non-Hodgkin’s Lymphoma Overview
- Non-Hodgkin’s Lymphoma- Analytical Perspective In-depth Commercial Assessment
- Non-Hodgkin’s Lymphoma Pipeline Therapeutics
- Non-Hodgkin’s Lymphoma Late Stage Products (Phase II/III)
- Non-Hodgkin’s Lymphoma Mid Stage Products (Phase II)
- Non-Hodgkin’s Lymphoma Early Stage Products (Phase I)
- Non-Hodgkin’s Lymphoma Preclinical Stage Products
- Non-Hodgkin’s Lymphoma Therapeutics Assessment
- Non-Hodgkin’s Lymphoma Inactive Products
- Company-University Collaborations (Licensing/Partnering) Analysis
- Non-Hodgkin’s Lymphoma Key Companies
- Non-Hodgkin’s Lymphoma Key Products
- Non-Hodgkin’s Lymphoma Unmet Needs
- 16 . Non-Hodgkin’s Lymphoma Market Drivers and Barriers
- Non-Hodgkin’s Lymphoma Future Perspectives and Conclusion
- Non-Hodgkin’s Lymphoma Analyst Views
- Appendix
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