DelveInsight’s “Hypophosphatasia Market Insights, Epidemiology, and Market Forecast-2034″ report offers an in-depth understanding of the Hypophosphatasia, historical and forecasted epidemiology as well as the Hypophosphatasia market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

To Know in detail about the Hypophosphatasia market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Hypophosphatasia Market Forecast

Some of the key facts of the Hypophosphatasia Market Report: 

• The Hypophosphatasia market size was valued at ~USD 880 Million in the year 2023 and is anticipated to grow with a significant CAGR during the study period (2020-2034)

• The pipeline for Hypophosphatasia is not very robust, consisting of REC-01, ALXN1850, and others which are expected to launch during the forecast period [2022-2032]

• According to DelveInsight’s analysis, the diagnosed prevalent cases of Hypophosphatasia in the 7MM were estimated to be around 6,500 in 2023. This number is expected to rise by 2034 due to increased disease awareness among healthcare professionals and the general public worldwide.

• In 2023, the US reported the highest diagnosed prevalence of hypophosphatasia among the 7MM, with approximately 6,000 cases. These numbers are expected to grow from 2024 to 2034, largely due to advancements in genetic testing that have enabled expanded newborn screening programs across the country.

• Among the EU4 countries and the UK, Germany reported the highest number of diagnosed hypophosphatasia cases, with about 84 cases, followed by France with 69 cases, and the UK with 68 cases. These numbers are expected to increase by 2034, driven by a heightened focus on research and clinical trials for the disease.

• In the UK, mild hypophosphatasia cases accounted for nearly 82%, moderate cases for 16%, and severe cases for 2% in 2023. The number of cases for each severity level is expected to rise by 2034.

• Key Hypophosphatasia Companies: PuREC, AstraZeneca, Ultragenyx Pharmaceutical Inc., Alexion, and others

• Key Hypophosphatasia Therapies: REC-01, ALXN1850, BPS804, asfotase alfa, and others

• The Hypophosphatasia epidemiology based on severity-specific cases analyzed that mild Hypophosphatasia was most prevalent in the US, followed by moderate and severe Hypophosphatasia

• The Hypophosphatasia market is expected to surge due to the disease’s increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Hypophosphatasia pipeline products will significantly revolutionize the Hypophosphatasia market dynamics.

Hypophosphatasia Overview

Hypophosphatasia is defined as a rare, genetic metabolic disorder characterized by impaired mineralization of bones and teeth, according to National Organization for Rare Disorders (NORD). Defective mineralization results in bones that are soft and prone to fracture and deformity and it also leads to tooth loss. Depending on the specific form, it can be inherited in an autosomal recessive or dominant manner.

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Hypophosphatasia Epidemiology

The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2020 to 2034. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Hypophosphatasia Epidemiology Segmentation:

The Hypophosphatasia market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into:

• Total Prevalence of Hypophosphatasia

• Prevalent Cases of Hypophosphatasia by severity

• Gender-specific Prevalence of Hypophosphatasia

• Diagnosed Cases of Episodic and Chronic Hypophosphatasia

Download the report to understand which factors are driving Hypophosphatasia epidemiology trends @ Hypophosphatasia Epidemiology Forecast

Hypophosphatasia Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Hypophosphatasia market or expected to get launched during the study period. The analysis covers Hypophosphatasia market uptake by drugs, patient uptake by therapies, and sales of each drug. 

Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.

The report also covers the Hypophosphatasia Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Hypophosphatasia Therapies and Key Companies

• REC-01: PuREC

• ALXN1850: AstraZeneca

• BPS804: Ultragenyx Pharmaceutical Inc

Discover more about therapies set to grab major Hypophosphatasia market share @ Hypophosphatasia Treatment Market

Hypophosphatasia Market Strengths

• Advancements in understanding the pathophysiology and genetics of Hypophosphatasia, thereby elucidating new targets for treatment

• The approval of ERT by various regulatory authorities is a game changer, improving clinical manifestations, survival, and QoL

Hypophosphatasia Market Barriers

• Developing specific biochemical biomarker-based assays with an increased understanding of differential diagnosis among physicians will lead to improvements in diagnosis, thus opening the windows of opportunity for new treatment options

• There is a need for pharmacotherapeutic interventions for milder adult-onset of disease, which has little mortality and a high disease burden

Scope of the Hypophosphatasia Market Report

• Study Period: 2020–2034

• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]

• Key Hypophosphatasia Companies: PuREC, AstraZeneca, Ultragenyx Pharmaceutical Inc., Alexion, and others

• Key Hypophosphatasia Therapies: REC-01, ALXN1850, BPS804, asfotase alfa, and others

• Hypophosphatasia Therapeutic Assessment: Hypophosphatasia current marketed and Hypophosphatasia emerging therapies

• Hypophosphatasia Market Dynamics: Hypophosphatasia market drivers and Hypophosphatasia market barriers 

• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies

• Hypophosphatasia Unmet Needs, KOL’s views, Analyst’s views, Hypophosphatasia Market Access and Reimbursement 

To know more about Hypophosphatasia companies working in the treatment market, visit @ Hypophosphatasia Clinical Trials and Therapeutic Assessment

Table of Contents 

1. Hypophosphatasia Market Report Introduction

2. Executive Summary for Hypophosphatasia

3. SWOT analysis of Hypophosphatasia

4. Hypophosphatasia Patient Share (%) Overview at a Glance

5. Hypophosphatasia Market Overview at a Glance

6. Hypophosphatasia Disease Background and Overview

7. Hypophosphatasia Epidemiology and Patient Population

8. Country-Specific Patient Population of Hypophosphatasia 

9. Hypophosphatasia Current Treatment and Medical Practices

10. Hypophosphatasia Unmet Needs

11. Hypophosphatasia Emerging Therapies

12. Hypophosphatasia Market Outlook

13. Country-Wise Hypophosphatasia Market Analysis (2020–2034)

14. Hypophosphatasia Market Access and Reimbursement of Therapies

15. Hypophosphatasia Market Drivers

16. Hypophosphatasia Market Barriers

17.  Hypophosphatasia Appendix

18. Hypophosphatasia Report Methodology

19. DelveInsight Capabilities

20. Disclaimer

21. About DelveInsight

About DelveInsight 

DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.

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