DelveInsight’s “Malignant Ascites Market Insights, Epidemiology, and Market Forecast-2034″ report offers an in-depth understanding of the Malignant Ascites, historical and forecasted epidemiology as well as the Malignant Ascites market trends in the United States, EU4 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
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Key Takeaways from the Malignant Ascites Market Report
- Among the 7MM, the United States accounted for the highest incident cases of Malignant ascites in 2020, with around 350,000 cases; these cases are expected to increase during the forecast period.
- Among all the associated cancers, the highest incident cases were reported in Breast Cancer. In 2020 the total incident cases of Breast Cancer were 640,000.
- In 2020, the total patient pool of Malignant Ascites were 390,000 in the EU4 and the UK.
- The leading Malignant Ascites Companies such as Clover Biopharmaceuticals, Wuhan YZY Biopharma Co., Ltd., Neovii Biotech, Jiangsu Simcere Pharmaceutical, Neovii Biotech, Sanofi, and others
- Promising Malignant Ascites Therapies such as SCB-313, M701, catumaxomab, Endostar, Catumaxomab, aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®), and others
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Malignant Ascites Epidemiology Segmentation in the 7MM
- Total Incident Cases of Ascites in Selected Indications (Ovarian, Colorectal, Gastric, and Others) in the 7MM
- Incident Cases of Malignant Ascites in Selected Indications in the 7MM
- Total Treated Cases of Malignant Ascites in the 7MM
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Malignant ascites Emerging Drugs Profile
- Catumaxomab: Lindis Biotech
Catumaxomab is a bispecific trifunctional antibody that binds directly to the tumor cell with one of its binding sites. It activates two essential components of the immune system with the other binding sites: T cells and macrophages (scavenger cells). The antibody recognizes and binds to all EpCAM-positive tumor cells, including critical cancer stem cells and all CD3-positive T cells. The EpCAM marker is present on almost all carcinomas and is, therefore, a promising approach for targeted cancer treatment. As per company pipeline, catumaxomab is in the preregistration stage of development for the treatment of Malignant ascites.
- M 701: Wuhan YZY Biopharma
M701 is a new biological Class I drug that targets both EpCAM and CD3 being developed by YBODY Biotech through its independently patented asymmetric bispecific antibody YBODY® platform. The drug is mainly used for the treatment of malignant ascites (MA) and malignant pleural effusion (MPE) derived from EpCAM-positive cancer.M701 dual-antibody targets the EpCAM antigen on one end. At the same time, the CD3 antibody on the other end can bridge T cells and activate T cells to kill EpCAM-positive tumor cells. Currently, M701 is in the Phase II stage of development for the treatment of malignant ascites.
Malignant Ascites Drugs Market Insights
Antibody-dependent cell cytotoxicity
Antibody-Dependent Cellular Cytotoxicity (ADCC) is a crucial mechanism of the immune system involving the targeting and destruction of pathogenic cells by effector cells, particularly natural killer (NK) cells. ADCC is a process where specific antibodies bind to pathogens, marking them for destruction by NK cells through the injection of cytotoxic factors, leading to cell lysis. Antibodies recognize and bind to target cells, which are then attacked and destroyed by effector cells like NK cells. This process plays a vital role in immune responses against pathogens and cancer cells.
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Malignant Ascites Therapies and Companies
- SCB-313: Clover Biopharmaceuticals
- M701: Wuhan YZY Biopharma Co., Ltd.
- catumaxomab: Neovii Biotech
- Endostar: Jiangsu Simcere Pharmaceutical
- Catumaxomab: Neovii Biotech
- aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®): Sanofi
Scope of the Malignant Ascites Market Report
- Study Period: 2020–2034
- Coverage: 7MM
- Malignant Ascites Companies: Clover Biopharmaceuticals, Wuhan YZY Biopharma Co., Ltd., Neovii Biotech, Jiangsu Simcere Pharmaceutical, Neovii Biotech, Sanofi, and others
- Malignant Ascites Therapies: SCB-313, M701, catumaxomab, Endostar, Catumaxomab, aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®), and others
- Malignant Ascites Therapeutic Assessment: Malignant Ascites current marketed and Malignant Ascites emerging therapies
- Malignant Ascites Market Dynamics: Malignant Ascites market drivers and Malignant Ascites market barriers
- Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies
- Malignant Ascites Unmet Needs, KOL’s views, Analyst’s views, Malignant Ascites Market Access and Reimbursement
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Table of Contents
1. Malignant Ascites Market Report Introduction
2. Executive Summary for Malignant Ascites
3. SWOT analysis of Malignant Ascites
4. Malignant Ascites Patient Share (%) Overview at a Glance
5. Malignant Ascites Market Overview at a Glance
6. Malignant Ascites Disease Background and Overview
7. Malignant Ascites Epidemiology and Patient Population
8. Country-Specific Patient Population of Malignant Ascites
9. Malignant Ascites Current Treatment and Medical Practices
10. Malignant Ascites Unmet Needs
11. Malignant Ascites Emerging Therapies
12. Malignant Ascites Market Outlook
13. Country-Wise Malignant Ascites Market Analysis (2020–2034)
14. Malignant Ascites Market Access and Reimbursement of Therapies
15. Malignant Ascites Market Drivers
16. Malignant Ascites Market Barriers
17. Malignant Ascites Appendix
18. Malignant Ascites Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight
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