The Acute Ischemic Stroke Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

“Acute Ischemic Stroke Pipeline Insight, 2023“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Acute Ischemic Stroke Market.

Some of the key takeaways from the Acute Ischemic Stroke Pipeline Report:

• Companies across the globe are diligently working toward developing novel Acute Ischemic Stroke treatment therapies with a considerable amount of success over the years. 
• Acute Ischemic Stroke companies working in the treatment market are Revalesio Corporation, Biogen, ZZ Biotech, Saillant Therapeutics, Avilex Pharma, NeuroTrauma Science, Prolong Pharmaceuticals, Ever Supreme Bio Technology, NC Medical Research, Inc., Lumosa Therapeutics Co., Ltd., NoNO Inc., GNT Pharma, Genentech, and others, are developing therapies for the Acute Ischemic Stroke treatment 

• Emerging Acute Ischemic Stroke therapies in the different phases of clinical trials are- RNS60, BIIB131 (TMS-007), 3K3A-APC, ST-01, AVLX 144, NTS-104, PP-007, UMSC01, NCS-01, LT3001, Nerinetide, Nelonemdaz, Tenecteplase, and others are expected to have a significant impact on the Acute Ischemic Stroke market in the coming years.   
• In May 2022, Boehringer Ingelheim has commenced a study named “DIRECT Thrombectomy vs. Intravenous TNK plus Thrombectomy,” focusing on the comparison between Endovascular Treatment alone and Endovascular Treatment preceded by systemic thrombolysis with Tenecteplase in cases of Acute Ischemic Stroke caused by significant intracranial vessel occlusion.
• In February 2022, Lumosa Therapeutics Co., Ltd. has launched a Phase II clinical trial comprising two parts, designed as a double-blind, randomized, and placebo-controlled study. The trial aims to assess the safety and effectiveness of the LT3001 drug product in individuals experiencing Acute Ischemic Stroke (AIS) and undergoing endovascular thrombectomy (EVT). Participants in this study are expected to receive the standard of care (SoC) for AIS treatments as deemed suitable.
• In February 2022, Acticor Biotech released encouraging results from its Phase Ib/IIa ACTIMIS clinical trial evaluating glenzocimab as an additional therapy alongside standard care for patients with acute ischemic stroke (AIS). The study successfully achieved its primary objective, demonstrating the favorable safety profile of glenzocimab.
• In February 2022, Bayer revealed that the U.S. Food and Drug Administration (FDA) has awarded Fast Track Designation to its investigative medication asundexian (BAY2433334) for potential use as a treatment in secondary prevention for patients who have experienced non-cardioembolic ischemic stroke.

Acute Ischemic Stroke Overview

Acute stroke is categorized as either ischemic or hemorrhagic, often sharing certain risk factors and clinical features but requiring distinct approaches to management. This condition constitutes a medical urgency triggered by reduced blood flow to the brain, leading to the impairment or damage of brain cells.

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Emerging Acute Ischemic Stroke Drugs Under Different Phases of Clinical Development Include:

• RNS60: Revalesio Corporation
• BIIB131 (TMS-007): Biogen
• 3K3A-APC: ZZ Biotech
• ST-01: Saillant Therapeutics
• AVLX 144: Avilex Pharma
• NTS-104: NeuroTrauma Science
• PP-007: Prolong Pharmaceuticals
• UMSC01: Ever Supreme Bio Technology
• NCS-01: NC Medical Research, Inc.
• LT3001: Lumosa Therapeutics Co., Ltd.
• Nerinetide: NoNO Inc.
• Nelonemdaz: GNT Pharma
• Tenecteplase: Genentech

Acute Ischemic Stroke Route of Administration

Acute Ischemic Stroke pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

• Intra-articular
• Intraocular
• Intrathecal
• Intravenous
• Ophthalmic
• Oral
• Parenteral
• Subcutaneous
• Topical
• Transdermal

Acute Ischemic Stroke Molecule Type

Acute Ischemic Stroke Products have been categorized under various Molecule types, such as

• Oligonucleotide
• Peptide
• Small molecule

Acute Ischemic Stroke Pipeline Therapeutics Assessment

• Acute Ischemic Stroke Assessment by Product Type
• Acute Ischemic Stroke By Stage and Product Type
• Acute Ischemic Stroke Assessment by Route of Administration
• Acute Ischemic Stroke By Stage and Route of Administration
• Acute Ischemic Stroke Assessment by Molecule Type
• Acute Ischemic Stroke by Stage and Molecule Type

DelveInsight’s Acute Ischemic Stroke Report covers around 35+ products under different phases of clinical development like

• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Acute Ischemic Stroke product details are provided in the report. Download the Acute Ischemic Stroke pipeline report to learn more about the emerging Acute Ischemic Stroke therapies

Some of the key companies in the Acute Ischemic Stroke Therapeutics Market include:

Key companies developing therapies for Acute Ischemic Stroke are – Genentech, Inc., NoNO Inc., Pharming Technologies B.V., Biogen, Avilex Pharma, SanBio, ZZ Biotech, Revalesio, Stemedica Cell Technologies, StemCyte, Ninnion, Athersys, Inc., Tarveda Therapeutics, Lumosa Therapeutics, NC Medial Research Inc, Acticor Biotech, Meridigen Biotech Co., Prolong Pharmaceuticals, Nanjing Yoko Biomedical Co., Ltd., TrueBinding, Inc., GNT Pharma, Roche, DiaMedica Therapeutics Inc, aptaTargets, Bristol-Myers Squibb, NuvOX Pharma, Simcere Pharmaceutical Co., Ltd., Algernon Pharmaceuticals, Primary Peptides, TMS, Tasly Pharmaceutical, Pharmazz and others.

Acute Ischemic Stroke Pipeline Analysis:

The Acute Ischemic Stroke pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the treatment of Acute Ischemic Stroke with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Acute Ischemic Stroke Treatment.
• Acute Ischemic Stroke key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Acute Ischemic Stroke Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Acute Ischemic Stroke market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

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Acute Ischemic Stroke Pipeline Market Drivers

• Rising incidence of Acute Ischemic Stroke, increasing prevalence of lifestyle associated disorders such as diabetes and hypertension, rising geriatric population are some of the important factors that are fueling the Acute Ischemic Stroke Market.

Acute Ischemic Stroke Pipeline Market Barriers

• However, challenges associated with the clinical research, challenges associated with the diagnosis of Acute Ischemic Stroke and other factors are creating obstacles in the Acute Ischemic Stroke Market growth.

Scope of Acute Ischemic Stroke Pipeline Drug Insight    

• Coverage: Global
• Key Acute Ischemic Stroke Companies: Revalesio Corporation, Biogen, ZZ Biotech, Saillant Therapeutics, Avilex Pharma, NeuroTrauma Science, Prolong Pharmaceuticals, Ever Supreme Bio Technology, NC Medical Research, Inc., Lumosa Therapeutics Co., Ltd., NoNO Inc., GNT Pharma, Genentech, and others
• Key Acute Ischemic Stroke Therapies: RNS60, BIIB131 (TMS-007), 3K3A-APC, ST-01, AVLX 144, NTS-104, PP-007, UMSC01, NCS-01, LT3001, Nerinetide, Nelonemdaz, Tenecteplase, and others
• Acute Ischemic Stroke Therapeutic Assessment: Acute Ischemic Stroke current marketed and Acute Ischemic Stroke emerging therapies
• Acute Ischemic Stroke Market Dynamics: Acute Ischemic Stroke market drivers and Acute Ischemic Stroke market barriers 

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Table of Contents

1. Acute Ischemic Stroke Report Introduction

2. Acute Ischemic Stroke Executive Summary

3. Acute Ischemic Stroke Overview

4. Acute Ischemic Stroke- Analytical Perspective In-depth Commercial Assessment

5. Acute Ischemic Stroke Pipeline Therapeutics

6. Acute Ischemic Stroke Late Stage Products (Phase II/III)

7. Acute Ischemic Stroke Mid Stage Products (Phase II)

8. Acute Ischemic Stroke Early Stage Products (Phase I)

9. Acute Ischemic Stroke Preclinical Stage Products

10. Acute Ischemic Stroke Therapeutics Assessment

11. Acute Ischemic Stroke Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. Acute Ischemic Stroke Key Companies

14. Acute Ischemic Stroke Key Products

15. Acute Ischemic Stroke Unmet Needs

16 . Acute Ischemic Stroke Market Drivers and Barriers

17. Acute Ischemic Stroke Future Perspectives and Conclusion

18. Acute Ischemic Stroke Analyst Views

19. Appendix

20. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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