Acute Kidney Injury (AKI), also known as acute renal failure (ARF), is a sudden episode of kidney failure or kidney damage. AKI is characterized by abrupt deterioration in kidney function, manifested by an increase in serum creatinine level with or without reduced urine output.
DelveInsight’s, “Acute Kidney Injury Pipeline Insight, 2022” report provides comprehensive insights about 30+ companies and 30+ pipeline drugs in Acute Kidney Injury pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
To know more Acute Kidney Injury pipeline report offerings, click here: Acute Kidney Injury Pipeline Insight
Key Takeaways from the Acute Kidney Injury Pipeline Report
- DelveInsight’s Acute Kidney Injury Pipeline report depicts a robust space with 25+ active players working to develop 25+ pipeline therapies for Acute Kidney Injury treatment.
- The major Acute Kidney Injury companies include Atox Bio, AM Pharma Holding, Quark-Pharmaceuticals, LG Chem, Pharming Group, Angion Biomedica, Elysium Health, Sentien Biotechnologies, Pharmazz, Arch Biopartners, Guard Therapeutics, RegeneRx Biopharmaceuticals, Cerenis Therapeutics Alloksys, Vifor Pharma, Exponential Biotherapies, Astellas Pharma, Amniotics, Mission Therapeutics, Bessor pharma, Kantum Pharma, Nephraegis Therapeutics, Vasomune, Unicycive, ABIONYX and others are developing novel drug candidates to improve the Acute Kidney Injury treatment landscape.
- Key Acute Kidney Injury pipeline therapies in various stages of development include bRESCAP, ANG-3777, EA-230, Ilofotase alfa, ASP1128, Ruconest (Conestat alfa), UMC 119 06, Kidney specific amniotic mesenchymal stem cell therapy, RMC 035, SBI-101, QPI-1002, RMC035, MIB-626, RBT-9, Recombinant human alkaline phosphatase, XRx-101, SUL-138, UNI494, Timbetasin, and others.
- In March 2022, at the 27th International Conference on Advances in Critical Care Nephrology, AM-Pharma will deliver an overview of the current Phase III REVIVAL study.
- In September 2021, AM-Pharma agreed to an exclusive licensing deal with Kyowa Kirin giving Kyowa Kirin the rights to develop and sell ilofotase alfa in Japan.
- Angion and Vifor publicly published findings on ANG-3777 clinical trials in 2021, including a Phase II CSA-AKI trial and a Phase III DGF trial.
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A snapshot of the Acute Kidney Injury Pipeline Drugs mentioned in the report:
Drugs |
Company |
Phase |
MoA |
RoA |
ANG-3777 |
Angion Biomedica/Vifor Pharma |
Phase II |
Proto oncogene protein c met stimulant |
Intravenous |
Ilofotase alfa |
AM Pharma |
Phase III |
Endotoxin inhibitors; Enzyme replacements |
NA |
ASP1128 |
Astellas Pharma |
Phase II |
Peroxisome proliferator-activated receptor delta modulators |
Intravenous |
Ruconest (Conestat alfa) |
Pharming Technologies |
Phase II |
Complement C1 inhibitor protein replacements; Complement C1r inhibitors; Complement C1s inhibitors |
Intravenous |
RMC-035 |
Guard Therapeutics |
Phase II |
Alpha 1 microglobulin replacements |
Intravenous |
SBI-101 |
Sentien Biotechnologies |
Phase I/II |
Stem cell modulators |
Parenteral |
Timbetasin |
RegeneRx Biopharmaceuticals |
Preclinical |
Actin modulators; Amyloid inhibitors |
NA |
Learn more about the novel and emerging Acute Kidney Injury pipeline therapies @ Acute Kidney Injury Clinical Trials
DelveInsight’s Acute Kidney Injury report covers around 40+ products under different phases of clinical development like:
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
Request for free Sample Report to get detailed information about the recent developments in Acute Kidney Injury treatment landscape: Acute Kidney Injury Treatment and Medication
Scope of the Acute Kidney Injury Pipeline Report
- Coverage: Global
- Key Acute Kidney Injury Companies: Atox Bio, AM Pharma Holding, Quark-Pharmaceuticals, LG Chem, Pharming Group, Angion Biomedica, Elysium Health, Sentien Biotechnologies, Pharmazz, Arch Biopartners, Guard Therapeutics, RegeneRx Biopharmaceuticals, Cerenis Therapeutics Alloksys, Vifor Pharma, Exponential Biotherapies, Astellas Pharma, Pharming Technologies, and others.
- Key Acute Kidney Injury Pipeline Therapies: bRESCAP, ANG-3777, EA-230, Ilofotase alfa, ASP1128, Ruconest (Conestat alfa), and others.
- Therapeutics Assessment By Mechanism of Action: Alpha 1 microglobulin replacements, Antioxidants, Free radical scavengers, Haemoglobin inhibitors, Decyclizing heme oxygenase inhibitors, Immunomodulators, Virus replication inhibitors, CD28 antigen modulators, Immunomodulators, Cell replacements, RNA interference, Tumour suppressor protein p53 inhibitors
To know more about the latest FDA approvals of Acute Kidney Injury drugs, click here: Acute Kidney Injury therapies and drugs
Table of Contents:
Introduction
Executive Summary
Acute Kidney Injury: Overview
Pipeline Therapeutics
• Comparative Analysis
Therapeutic Assessment
Acute Kidney Injury – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
Acute Kidney Injury Collaboration Deals
Late Stage Products (Phase III)
• Comparative Analysis
Teprasiran: Quark-Pharmaceuticals
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
• Comparative Analysis
EH 301: Elysium Health
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
• Comparative Analysis
Centhaquine: Pharmazz
Drug profiles in the detailed report…..
Preclinical/Discovery Stage Products
• Comparative Analysis
Timbetasin: RegeneRx Biopharmaceuticals
Drug profiles in the detailed report…..
Inactive Products
• Comparative Analysis
Acute Kidney Injury Key Companies
Acute Kidney Injury Key Products
Acute Kidney Injury- Unmet Needs
Acute Kidney Injury- Market Drivers and Barriers
Acute Kidney Injury- Future Perspectives and Conclusion
Acute Kidney Injury Analyst Views
Acute Kidney Injury Key Companies
Appendix
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