Acute Kidney Injury Market, Epidemiology, Treatment, Therapies, Drugs and Key Companies by DelveInsight

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Acute Kidney Injury Market, Epidemiology, Treatment, Therapies, Drugs and Key Companies by DelveInsight
Acute Kidney Injury Market

Acute Kidney Injury Market Insights, Epidemiology and Market Forecast- 2030‘ report delivers an in-depth understanding of the Acute Kidney Injury, historical and forecasted epidemiology as well as the Acute Kidney Injury market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), And Japan.

 

Acute Kidney Injury Epidemiology

The Acute Kidney Injury epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Total Incident Population of Acute Kidney Injury (AKI) in Hospitalized Patients, Mortality Adjusted Incident Population of AKI in Hospitalized Patients, Stage-specific Incident Population of AKI, and Age-specific Incident Population of AKI in the United States, EU5 countries (Germany, France, Italy, Spain, and United Kingdom), and Japan.

 

Key Findings of Acute Kidney Injury Epidemiology:

  • In 2020, the incident population of AKI in the 7MM was 10,907,615. The mortality adjusted incident population of AKI in hospitalized patients in the seven major market, was estimated to be 6,544,569 in 2020.
  • The United States encompasses the highest incident population of AKI in hospitalized patients, compared to EU5 and Japan. In the United States, mortality adjusted incident population of AKI in hospitalized patients accounted for 2,231,147 in 2020.
  • In 2020, in the United States, there were 1,584,114, 401,606, and 245,426 cases of stage I, stage II, and stage III AKI respectively.
  • In the US, the age group of 60-84 accounted for the highest cases in 2020, followed by 85+ years. In contrast, the least cases were found in the age group of 18-59.
  • In 2020, there were 312,361, 1,004,016, and 914,770 cases, for the age groups 18-59 years, 60-84 years, and 85+ years, respectively.
  • Epidemiology assessed for Acute Kidney Injury showed that Germany accounted for the highest mortality-adjusted incident population of AKI in hospitalized patients in EU5, followed by the UK in 2020.
  • The number of total mortality adjusted incidence of AKI in hospitalized patients is anticipated to be 906,731, 544,235, 506,725, 235,769 and 796,443 in 2020, for Germany, France, Italy, Spain, and UK, respectively.
  • Epidemiology assessed for AKI showed that Japan, in 2020, accounted for the second-highest mortality-adjusted incident population of AKI in hospitalized patients in 7MM, about 1,323,519 cases.

 

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Key Findings of Acute Kidney Injury Market Outlook

  • The total Acute Kidney Injury market size is calculated by including the market size of both emerging and current therapies. The total Acute Kidney Injury market size in the 7MM was estimated to be USD 5,436 million in 2020 during the study period 2018-2030.
  • In the 7MM, most of the share in the current market was captured by the United States, which was USD 2,786.7 million, while the second-highest revenue generator was Japan, taking nearly USD 840.4 million in its box, in 2020.The dynamics are anticipated to change during the forecast period, i.e., 2021-2030, owing to the launch of more effective drugs with clinically improved outcomes.
  • Among the 7MM countries, the US accounts for the largest Acute Kidney Injury market size. The growth of market size for AKI is attributed to emerging therapies. The market size for AKI was USD 2,786.7 million in 2020.
  • Among the EU-5 countries, Germany accounted for the highest market size of AKI in 2020. The market size of AKI in the EU5 was USD 1,809 million in 2020, inclusive of current treatment regimens. The lowest market is estimated to be covered by Spain, which accounts for USD 142.6 million in 2020.
  • The market size for AKI in Japan was calculated to be USD 840.4 million in 2020.

 

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Analyst Comments

  • Since AKI is associated with multiple critical care complications such as cardiac surgery, DGF, sepsis, and many more, no targeted pharmacotherapies have been approved for AKI treatment. Consequently, the treatment solely depends on the existing off-label therapeutic options, such as diuretics, NSAIDs, RRT, etc., which have been used for decades.
  • As there is no therapeutic cure to the disease, the risk of AKI is usually prevented by identifying patients at risk, reviewing medications, and reducing the exposure of patients to nephrotoxic drugs. The current treatment approach for such patients needs to be on the preventive side rather than on the curative side. Therefore, the emerging drugs such as bRESCAP, ANG-3777 for AKI-associated with cardiac surgery, QPI-1002, and Ruconest (Conestat alfa) are aiming to prevent the risk of AKI rather than providing therapeutic support after the cause of AKI.
  • Amongst upcoming emerging therapies, ANG-3777 and teprasiran (QPI-1002) for DGF indication are expected to get approval earlier than AKI-associated with cardiac surgery. ANG-3777 has received the Fast Track and Orphan Drug designation by the US FDA and is planning to submit NDA by 2022 for DGF. QPI-1002, on the other hand, has been granted Orphan Drug designation by the US FDA and EU and is aiming to support NDA submission for the DGF indication. Besides, recAP and bRESCAP are also among the key players in the late phases of development and are expected to enter the market soon.

 

Acute Kidney Injury Companies Mentioned

  • Alloksys
  • Angion Biomedica
  • Quark Pharmaceuticals
  • AM-Pharma
  • Astellas Pharma
  • Pharming Technologies
  • Exponential Biotherapies
  • Atox Bio
  • And Many Others

 

Table of Contents:

1. Key Insights

2. Executive Summary of Acute Kidney Injury

3. Competitive Intelligence Analysis for Acute Kidney Injury

4. Acute Kidney Injury: Market Overview at a Glance

5. Acute Kidney Injury: Disease Background and Overview

6. Patient Journey

7. Acute Kidney Injury Epidemiology and Patient Population

8. Treatment Algorithm, Current Treatment, and Medical Practices

9. Unmet Needs

10. Key Endpoints of Acute Kidney Injury Treatment

11. Marketed Products

List to be continued in report

12. Emerging Therapies

List to be continued in report

13. Acute Kidney Injury: Seven Major Market Analysis

14. Attribute analysis

15. 7MM: Market Outlook

16. Access and Reimbursement Overview of Acute Kidney Injury

17. KOL Views

18. Market Drivers

19. Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

 

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.  Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.

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