DelveInsight’s “Advanced Renal Cell Carcinoma Market Insights, Epidemiology, and Market Forecast-2034″ report offers an in-depth understanding of the Antibody Drug Conjugates, historical and forecasted epidemiology as well as the Antibody Drug Conjugates market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

To Know in detail about the Advanced Renal Cell Carcinoma market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Advanced Renal Cell Carcinoma Market Forecast

Some of the key facts of the Advanced Renal Cell Carcinoma Market Report: 

• The Advanced Renal Cell Carcinoma market size is anticipated to grow with a significant CAGR during the study period (2020-2034)

• In December 2023, Exelixis and Arcus Biosciences have announced a collaborative effort for the STELLAR-009 clinical trial, a Phase Ib/II study assessing zanzalintinib, Exelixis’ advanced tyrosine kinase inhibitor (TKI), in conjunction with AB521, a transcription factor HIF-2⍺ inhibitor, in patients with advanced solid tumors, including ccRCC. Exelixis is leading the sponsorship of the STELLAR-009 trial, while Arcus is contributing to the funding and providing AB521 for the study. Patient recruitment for the STELLAR-009 trial is anticipated to commence by the conclusion of 2023.

• In July 2023, The Chinese National Medical Products Administration (NMPA) has assessed a supplementary new drug application (sNDA) seeking approval for the utilization of toripalimab (Tuoyi) in conjunction with axitinib (Inlyta) as a primary treatment option for patients afflicted with unresectable or metastatic renal cell carcinoma (RCC). This submission is supported by data obtained from an interim analysis of the phase 3 RENOTORCH trial (NCT04394975), revealing that the combined treatment regimen led to improved progression-free survival (PFS) in comparison to the use of the single-agent sunitinib (Sutent).

• In April 2023, At the American Association for Cancer Research (AACR) Annual Meeting in Orlando, Florida, Allogene Therapeutics presented interim results from its Phase 1 TRAVERSE trial, which focuses on ALLO-316, the company’s primary AlloCAR T investigational product developed for treating solid tumors. The data exhibited encouraging early antitumor effects and a favorable safety profile of the novel anti-CD70 allogeneic CAR T-cell therapy, ALLO-316, particularly when administered at lower doses. These findings suggest that this treatment regimen holds promise as a potential new therapeutic approach for heavily treated patients with advanced clear cell renal cell carcinoma (ccRCC) expressing CD70.

• In April 2023, Shanghai Junshi Biosciences Co., Ltd. has reported the completion of the planned interim analysis for the RENOTORCH trial (NCT04394975). This phase 3 clinical trial is a multicenter, randomized, open-label study investigating the efficacy of combining toripalimab with axitinib as a first-line therapy for patients with intermediate to high-risk, unresectable, or metastatic renal cell carcinoma (RCC). The Independent Data Monitoring Committee (IDMC) has verified that the primary endpoint of progression-free survival (PFS), assessed through an independent radiographic review, has met the predetermined efficacy criteria.

• In January 2023, Teon Therapeutics announced a partnership with Merck, with a particular emphasis on the combination arm of Teon’s current clinical trial. The trial comprises two arms: an open-label, dose escalation, and expansion phase. Its objective is to evaluate TT-816, Teon’s oral immune response modifier, in combination with Merck’s anti-PD-1 therapy, KEYTRUDA® (pembrolizumab), for patients dealing with advanced solid tumors.

• The Canadian Medical Association Journal (CMAJ) of 2024 states that the occurrence of RCC rises as individuals get older, typically diagnosed around the age of 75 globally. Additionally, males are twice as likely as females to develop this condition.

• As per the Canadian Medical Association Journal (CMAJ) in 2024, the general survival expectancy for metastatic RCC is roughly 4 years. Nevertheless, this duration may fluctuate based on variables like the patient’s age, performance level, and any accompanying health conditions.

• Key Advanced Renal Cell Carcinoma Companies: Dana-Farber Cancer Institute, Huabo Biopharm Co., Ltd., Beijing Scitech-Mq Pharmaceuticals, Oxford BioMedica, Hutchison Medipharma Limited, Takeda, Amgen, Novartis, AVEO Pharmaceuticals, Inc., Merck Sharp & Dohme LLC, Pfizer, Calithera Biosciences, Inc, AbbVie, Bristol-Myers Squibb, Abbott, SCRI Development Innovations, LLC, Astellas Pharma Inc, and others

• Key Advanced Renal Cell Carcinoma Therapies: Bevacizumab, HB0025, ST-1898 tablets, Trovax, fruquintinib+sintilimab, Cabozantinib, AMG 102, Pazopanib, tivozanib (AV-951), Belzutifan, Temsirolimus (CCI-779), CB-839, ABT-869, Nivolumab, ABT-510/Thrombospondin-1 mimetic, bevacizumab, CP-461, and others

• The Advanced Renal Cell Carcinoma epidemiology based on gender analyzed that Males are slightly more affected in the case of Advanced Renal Cell Carcinoma

• The Advanced Renal Cell Carcinoma market is expected to surge due to the disease’s increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Advanced Renal Cell Carcinoma pipeline products will significantly revolutionize the Advanced Renal Cell Carcinoma market dynamics.

Advanced Renal Cell Carcinoma Overview

Advanced Renal Cell Carcinoma (RCC), also known as advanced kidney cancer, refers to cancer that has spread beyond the kidney and nearby lymph nodes to other parts of the body. Renal cell carcinoma originates in the cells of the kidney’s tubules, which are tiny tubes that filter blood and remove waste products to form urine.

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Advanced Renal Cell Carcinoma Epidemiology

The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2020 to 2034. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Advanced Renal Cell Carcinoma Epidemiology Segmentation:

The Advanced Renal Cell Carcinoma market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into:

• Total Prevalence of Advanced Renal Cell Carcinoma

• Prevalent Cases of Advanced Renal Cell Carcinoma by severity

• Gender-specific Prevalence of Advanced Renal Cell Carcinoma

• Diagnosed Cases of Episodic and Chronic Advanced Renal Cell Carcinoma

Download the report to understand which factors are driving Advanced Renal Cell Carcinoma epidemiology trends @ Advanced Renal Cell Carcinoma Epidemiology Forecast

Advanced Renal Cell Carcinoma Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Advanced Renal Cell Carcinoma market or expected to get launched during the study period. The analysis covers Advanced Renal Cell Carcinoma market uptake by drugs, patient uptake by therapies, and sales of each drug. 

Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.

The report also covers the Advanced Renal Cell Carcinoma Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Advanced Renal Cell Carcinoma Therapies and Key Companies

• Bevacizumab: Dana-Farber Cancer Institute

• HB0025: Huabo Biopharm Co., Ltd.

• ST-1898 tablets: Beijing Scitech-Mq Pharmaceuticals

• Trovax: Oxford BioMedica

• fruquintinib+sintilimab: Hutchison Medipharma Limited

• Cabozantinib: Takeda

• AMG 102: Amgen

• Pazopanib: Novartis

• tivozanib (AV-951): AVEO Pharmaceuticals, Inc.

• Belzutifan: Merck Sharp & Dohme LLC

• Temsirolimus (CCI-779): Pfizer

• CB-839: Calithera Biosciences, Inc

• ABT-869: AbbVie

• Nivolumab: Bristol-Myers Squibb

• ABT-510/Thrombospondin-1 mimetic: Abbott

• bevacizumab: SCRI Development Innovations, LLC

• CP-461: Astellas Pharma Inc

Discover more about therapies set to grab major Advanced Renal Cell Carcinoma market share @ Advanced Renal Cell Carcinoma Treatment Landscape

Advanced Renal Cell Carcinoma Market Strengths

• The incidence of RCC has increased in recent years leading to more focus by pharmaceutical firms. 

• Antiangiogenics in association with targeted immunotherapy is overcoming resistance emphasizing the role of the tumor microenvironment (TME) and this strategy is currently an option in first line treatment.

Advanced Renal Cell Carcinoma Market Opportunities

•  There are ongoing trials addressing unanswered questions, such as (CAR) T-cell therapy.

Scope of the Advanced Renal Cell Carcinoma Market Report

• Study Period: 2020–2034

• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]

• Key Advanced Renal Cell Carcinoma Companies: Dana-Farber Cancer Institute, Huabo Biopharm Co., Ltd., Beijing Scitech-Mq Pharmaceuticals, Oxford BioMedica, Hutchison Medipharma Limited, Takeda, Amgen, Novartis, AVEO Pharmaceuticals, Inc., Merck Sharp & Dohme LLC, Pfizer, Calithera Biosciences, Inc, AbbVie, Bristol-Myers Squibb, Abbott, SCRI Development Innovations, LLC, Astellas Pharma Inc, and others

• Key Advanced Renal Cell Carcinoma Therapies: Bevacizumab, HB0025, ST-1898 tablets, Trovax, fruquintinib+sintilimab, Cabozantinib, AMG 102, Pazopanib, tivozanib (AV-951), Belzutifan, Temsirolimus (CCI-779), CB-839, ABT-869, Nivolumab, ABT-510/Thrombospondin-1 mimetic, bevacizumab, CP-461, and others

• Advanced Renal Cell Carcinoma Therapeutic Assessment: Advanced Renal Cell Carcinoma current marketed and Advanced Renal Cell Carcinoma emerging therapies

• Advanced Renal Cell Carcinoma Market Dynamics: Advanced Renal Cell Carcinoma market drivers and Advanced Renal Cell Carcinoma market barriers 

• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies

• Advanced Renal Cell Carcinoma Unmet Needs, KOL’s views, Analyst’s views, Advanced Renal Cell Carcinoma Market Access and Reimbursement 

To know more about Advanced Renal Cell Carcinoma companies working in the treatment market, visit @ Advanced Renal Cell Carcinoma Clinical Trials and Therapeutic Assessment

Table of Contents 

1. Advanced Renal Cell Carcinoma Market Report Introduction

2. Executive Summary for Advanced Renal Cell Carcinoma

3. SWOT analysis of Advanced Renal Cell Carcinoma

4. Advanced Renal Cell Carcinoma Patient Share (%) Overview at a Glance

5. Advanced Renal Cell Carcinoma Market Overview at a Glance

6. Advanced Renal Cell Carcinoma Disease Background and Overview

7. Advanced Renal Cell Carcinoma Epidemiology and Patient Population

8. Country-Specific Patient Population of Advanced Renal Cell Carcinoma 

9. Advanced Renal Cell Carcinoma Current Treatment and Medical Practices

10. Advanced Renal Cell Carcinoma Unmet Needs

11. Advanced Renal Cell Carcinoma Emerging Therapies

12. Advanced Renal Cell Carcinoma Market Outlook

13. Country-Wise Advanced Renal Cell Carcinoma Market Analysis (2020–2034)

14. Advanced Renal Cell Carcinoma Market Access and Reimbursement of Therapies

15. Advanced Renal Cell Carcinoma Market Drivers

16. Advanced Renal Cell Carcinoma Market Barriers

17.  Advanced Renal Cell Carcinoma Appendix

18. Advanced Renal Cell Carcinoma Report Methodology

19. DelveInsight Capabilities

20. Disclaimer

21. About DelveInsight

About DelveInsight 

DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.

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