Alagille Syndrome Market Report gives readers a thorough assessment of key market drivers, restraints, prospects, opportunities, restraints, current trends, and technological and industrial breakthroughs that will influence market growth. The detailed market research, industry sector growth and development, and new product introductions covered in this report on the Alagille Syndrome Market are of great assistance to the important new commercial players joining the market.
This Alagille Syndrome Market report research conducts a careful market evaluation and provides a professional analysis of the industry taking into account market development, present market circumstances, and forecasts for the future. The market driving factors, market overview, industry volume, and market share are also highlighted in this Alagille Syndrome Market report analysis.
Regions Covered in the Report-
- The United States
- EU5 (Germany, France, Italy, Spain, and the United Kingdom)
- Japan
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Alagille Syndrome: An Overview
Alagille Syndrome (ALGS) is a multisystem autosomal dominant disorder with a wide variety of clinical manifestations. It is also known as arteriohepatic dysplasia, Alagille-Watson syndrome, Watson-Miller syndrome or syndromic bile duct paucity. The clinical manifestations are variable, even within the same family, and commonly include hepatic (cholestasis, characterized by bile duct paucity on liver biopsy), cardiac (primarily involving the pulmonary arteries), renal skeletal (butterfly vertebrae), ophthalmologic (posterior embryotoxon), and facial abnormalities. It can range from a subclinical presentation to a life-threatening condition, with a mortality rate upto 10%.
Key highlights of the Alagille Syndrome Market Report
- As per the estimates by DelveInsight, the total cases of Alagille Syndrome in the seven major markets was 17,749.
- As per DelveInsight analysis, the United States showed the highest prevalent population of Alagille Syndrome. In 2021, the total prevalence in the United States were found to be 6,719.
- In 2021, the total prevalence of Alagille Syndrome in were found to be 2,395 which as per DelveInsight’s estimates, might decrease during the forecast period in Germany.
Alagille Syndrome Epidemiology Insights
The offspring of a patient with Alagille syndrome has a 50% chance of inheriting a gene mutation, whereas, among those affected with Alagille syndrome, 50% to 70% of individuals have a mutation de novo. No correlation has been found between a specific mutation and expressed phenotype. In more than 90 percent of cases, mutations in the JAG1 gene cause Alagille syndrome.
Alagille Syndrome Epidemiology Segmentation in the 7MM
- Total Prevalent Cases
- Gender-specific Prevalent Cases
- Diagnosed and Treatable Prevalent Cases
- Age-specific Prevalent Cases
Alagille Syndrome Treatment Market
Management of the disorder is aimed at preventing complications, increasing the flow of bile from the liver, maintaining normal growth and development and reducing blood cholesterol levels. Medicine may be used to increase bile flow and to relieve severe itching caused by buildup of bile in the blood and skin. These same medicines may be used to treat high cholesterol levels that cause the hard, whitish nodules that develop in the skin of patients with ALGS.
Alagille Syndrome Market Insights
Alagille syndrome is a rare genetic disorder that can affect multiple organ systems of the body including the liver, heart, skeleton, eyes and kidneys. The specific symptoms and severity of ALGS can vary greatly from one person to another, even within the same family. Some individuals may have mild forms of the disorder while others may have more serious forms.
Alagille Syndrome Market Forecast
Some affected infants and children with ALGS who do not respond to pharmacologic and dietary therapies may be treated by a surgical procedure known as partial biliary diversion. This surgical procedure is used to disrupt or divert recirculation of bile acids between the liver and the gastrointestinal tract.
Alagille Syndrome Market Size
The market size shall grow during the forecast period owing to the launch of upcoming therapies. The market size is expected to increase during the study period. Expected launch of the upcoming therapies shall fuel the growth of the market during the forecast period, i.e., 2022–2032
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Table of Content
- Key Insights
- Executive Summary
- Competitive Intelligence Analysis for Alagille Syndrome
- Alagille Syndrome Market Overview at a Glance
- Alagille Syndrome Disease Background and Overview
- Patient Journey
- Alagille Syndrome Epidemiology and Patient Population
- Treatment Algorithm, Current Treatment, and Medical Practices
- Alagille Syndrome Unmet Needs
- Key Endpoints of Alagille Syndrome Treatment
- Alagille Syndrome Marketed Products
- Alagille Syndrome Emerging Therapies
- Alagille Syndrome Seven Major Market Analysis
- Attribute analysis
- 7MM: Alagille Syndrome Market Outlook
- Access and Reimbursement Overview of Alagille Syndrome
- KOL Views
- Alagille Syndrome Market Drivers
- Alagille Syndrome Market Barriers
- Appendix
- DelveInsight Capabilities
- Disclaimer
- About DelveInsight
Alagille Syndrome Market Report Highlights
- In the coming years, the Alagille Syndrome market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
- The companies and academics are working to assess challenges and seek opportunities that could influence Alagille Syndrome R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition
- Major players are involved in developing therapies for Alagille Syndrome. The launch of emerging therapies will significantly impact the Alagille Syndrome market
- A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Alagille Syndrome
- Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities
Why should you buy this report?
- The report will help in developing business strategies by understanding trends shaping and driving the Alagille Syndrome market
- To understand the future market competition in the Alagille Syndrome market and Insightful review of the key market drivers and barriers
- Organize sales and marketing efforts by identifying the best opportunities for Alagille Syndrome in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
- Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
- Organize sales and marketing efforts by identifying the best opportunities for Alagille Syndrome market
- To understand the future market competition in the Alagille Syndrome market
About Us
DelveInsight is a Business Consulting and Market research company, providing expert business solutions for life science vertical and offering quintessential advisory services in the areas of R&D, Strategy Formulation, Operations, Competitive Intelligence, Competitive Landscaping, and Mergers & Acquisitions.
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