“Alpha-1 Antitrypsin Deficiency (AATD) Pipeline Insight, 2023” report by DelveInsight outlines a comprehensive assessment of the present clinical/non-clinical development activities and growth prospects across the Alpha-1 Antitrypsin Deficiency Market.
The Alpha-1 Antitrypsin Deficiency Pipeline report embraces in-depth commercial, regulatory, and Alpha-1 Antitrypsin Deficiency clinical trial assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the emerging Alpha-1 Antitrypsin Deficiency drugs, including the mechanism of action, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers, acquisition, funding, designations, and other product-related details.
Alpha-1 Antitrypsin Deficiency (AATD) Pipeline Analysis
The report provides insights into:
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The report provides detailed insights into the emerging therapies for Alpha-1 Antitrypsin Deficiency treatment and the aggregate therapies developed by major pharma companies.
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It accesses the different Alpha-1 Antitrypsin Deficiency therapies segmented into early-stage, mid-stage, and late-stage of clinical development.
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It outlines the major Alpha-1 Antitrypsin Deficiency companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
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The report evaluates the Alpha-1 Antitrypsin Deficiency drugs that are under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
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It navigates the major collaborations (company-company collaborations and company-academia collaborations), licensing agreements, financing details, data presentation by the pharma giants, and regulatory approval in the Alpha-1 Antitrypsin Deficiency therapeutic market.
Alpha-1 Antitrypsin Deficiency (AATD) Therapeutics Landscape
Several major pharma and biotech companies are developing therapies for Alpha-1 Antitrypsin Deficiency. Currently, Deerland Probiotics & Enzymes is leading the therapeutics market with its Alpha-1 Antitrypsin Deficiency drug candidates in the most advanced stage of clinical development.
Alpha-1 Antitrypsin Deficiency (AATD) Companies Actively Working in the Therapeutic Market Include:
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Octapharma
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Dicerna Pharmaceuticals
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Alnylam Pharmaceuticals
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Arrowhead Pharmaceuticals
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Vertex Pharmaceuticals
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AstraZeneca
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Kamada, Ltd
And Many Others
Emerging and Marketed Alpha-1 Antitrypsin Deficiency (AATD) Drugs Covered in the Report Include:
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ARO AAT: Arrowhead Pharmaceuticals
ARO AAT is a second-generation, N-Acetylgalactosamine (GalNAc) based, subcutaneously administered RNA interference-based therapeutic. ARO-AAT is designed to knock down the hepatic production of the mutant alpha-1 antitrypsin (Z-AAT) protein, the cause of progressive liver disease in AATD patients. In June 2019, the US FDA granted Fast Track designation to ARO-AAT. ARO-AAT is in Phase III clinical studies for the treatment of liver disease associated with alpha-1 antitrypsin deficiency (AATD).
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ALN-AAT02: Alnylam Pharmaceuticals
ALN AAT02 is a subcutaneously administered RNAi therapeutic that targets alpha-1 antitrypsin (AAT). ALN-AAT02 is based on Alnylam’s enhanced stabilization chemistry plus (ESC+)-GalNAc-conjugate technology, which enables subsequent subcutaneous dosing with increased selectivity and a wide therapeutic index. The drug is currently in Phase I/II clinical development for the treatment of ZZ Type AAT Deficiency Liver Disease.
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Analysis of Emerging Alpha-1 Antitrypsin Deficiency Therapies by Phases
The report covers the emerging products under different phases of clinical development like –
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Late-stage products (Phase III)
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Mid-stage products (Phase II)
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Early-stage product (Phase I)
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Pre-clinical and Discovery stage candidates
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Discontinued and inactive candidates
Route of Administration
Alpha-1 Antitrypsin Deficiency pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
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Intra-articular
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Intraocular
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Intrathecal
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Intravenous
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Ophthalmic
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Oral
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Parenteral
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Subcutaneous
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Topical
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Transdermal
Molecule Type
Products have been categorized under various Molecule types such as
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Oligonucleotide
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Peptide
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Small molecule
Learn How the Alpha-1 Antitrypsin Deficiency Treatment Outlook will Evolve with the Ongoing Clinical and commercial Activities in the Therapeutic Market @
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Table of Content (TOC)
1. Report Introduction
2. Executive Summary
3. Alpha-1 Antitrypsin Deficiency Treatment Patterns
4. Alpha-1 Antitrypsin Deficiency – DelveInsight’s Analytical Perspective
5. Therapeutic Assessment
6. Alpha-1 Antitrypsin Deficiency Late Stage Products (Phase-III)
7. Alpha-1 Antitrypsin Deficiency Mid-Stage Products (Phase-II)
8. Alpha-1 Antitrypsin Deficiency Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Alpha-1 Antitrypsin Deficiency Discontinued Products
13. Alpha-1 Antitrypsin Deficiency Product Profiles
14. Major Alpha-1 Antitrypsin Deficiency Companies in the Market
15. Key Products in the Alpha-1 Antitrypsin Deficiency Therapeutics Segment
16. Dormant and Discontinued Products
17. Alpha-1 Antitrypsin Deficiency Unmet Needs
18. Alpha-1 Antitrypsin Deficiency Future Perspectives
19. Alpha-1 Antitrypsin Deficiency Analyst Review
20. Appendix
21. Report Methodology
*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.
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About DelveInsight
DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.
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