Alzheimer’s disease attacks the cells of the brain and neurotransmitters, affecting the way brain functions, memory and behaviour. There is no known cure for the disease, and current approaches focus on helping people maintain mental function, manage behavioural symptoms, and slow down specific problems, such as memory loss. Two categories of drugs are approved for Alzheimer’s disease treatment: cholinesterase inhibitors and partial N-methyl D-aspartate (NMDA) antagonists.
Key benefits of Alzheimer’s disease market report
1. Alzheimer’s Disease market report covers a descriptive overview and comprehensive insight of the Alzheimer’s Disease epidemiology and Alzheimer’s Disease market in the 7 MM (the United States, EU5 (Germany, Spain, France, Italy, UK) & Japan.)
2. Alzheimer’s Disease market report provides insights into the current and emerging therapies.
3. Alzheimer’s Disease market report provides a global historical and forecasted market covering drug outreach in 7 MM.
4. Alzheimer’s Disease market report offers an edge that will help in developing business strategies by understanding trends shaping and driving the Alzheimer’s Disease market.
Cholinesterase inhibitors act by increasing the level of acetylcholine; a chemical used by nerve cells to communicate with each other and is vital for learning, memory, and cognitive functions. Of this category, three drugs: Donepezil (Aricept), Rivastigmine (Exelon), and Galantamine (Razadyne) are FDA-approved for the treatment of Alzheimer’s disease and are used to treat mild-to-moderate Alzheimer’s (donepezil can be used for severe Alzheimer’s as well). Donepezil can be used in all stages of Alzheimer disease. Galantamine and rivastigmine are approved for treatment in mild-to-moderate Alzheimer disease only. Donepezil and galantamine are rapid, reversible inhibitors of acetylcholinesterase. Rivastigmine is a slow, reversible inhibitor of acetylcholinesterase and butyrylcholinesterase. Most common side effects of cholinesterase inhibitors are gastrointestinal-like nausea, vomiting, and diarrhoea.
Partial N-Methyl D-aspartate (NMDA) antagonist includes memantine. Memantine (Namenda) is used to treat moderate-to-severe Alzheimer’s disease. However, these drugs do not change the underlying disease process. They are useful for some but not all people and may help only for a limited time. The FDA has also approved Aricept and Namzaric, a combination of Namenda and Aricept, for the treatment of moderate-to-severe Alzheimer’s disease. Dizziness, body aches, headache, and constipation are common side effects. It can be taken in combination with cholinesterase inhibitors.
Table of contents
1. Report Introduction
2. Alzheimer’s Disease Market Overview at a Glance
3. Alzheimer’s Disease Disease Background and Overview
4. Alzheimer’s Disease Epidemiology and Patient Population
5. Epidemiology of Alzheimer’s Disease by Countries (2017–2030)
5.1. United States- Epidemiology (2017–2030)
5.2. EU-5 – Epidemiology (2017–2030)
5.2.1. Assumptions and Rationale
5.2.2. Germany
5.2.3. France
5.2.4. Italy
5.2.5. Spain
5.2.6. United Kingdom
5.3. Japan
6. Alzheimer’s Disease Treatments & Medical Practices
7. Alzheimer’s Disease Marketed Products
7.1. Aricept: Eisai
7.2. Exelon: LTS Lohmann Therapie-Systeme/Novartis
7.3. Oligomannate: Green Valley Pharmaceuticals
8. Alzheimer’s Disease Emerging Therapies
8.1. Key Cross Competition
8.2. AGB101: AgeneBio
8.3. Bryostatin-1: Neurotrope Bioscience
8.4. COR388 HCL: Cortexyme
8.5. Eltoprazine: Amarantus Bioscience Holdings
8.6. ALZT-OP1: AZ Therapies
8.7. Brexpiprazole: Otsuka Pharmaceutical
8.8. AKST/GRF6019: Alkahest
8.9. AXS-05: Axsome Therapeutics
8.10. Tricaprilin: Cerecin
8.11. TRx0237: TauRx Therapeutics
8.12. RO7105705: Genentech
8.13. Azeliragon (TTP488): vTv Therapeutics
9. Alzheimer’s Disease Market Size
10. 7MM: Country-Wise Market Analysis
10.1. United States Market Size
10.2. Germany Market Size
10.3. France Market Size
10.4. Italy Market Size
10.5. Spain Market Size
10.6. United Kingdom Market Size
10.7. Japan Market Size
11. Market Drivers
12. Market Barriers
13. Alzheimer’s Disease Report Methodology
14. DelveInsight Capabilities
15. Disclaimer
16. About DelveInsight
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