Antiphospholipid Syndrome Market Report gives readers a thorough assessment of key market drivers, restraints, prospects, opportunities, restraints, current trends, and technological and industrial breakthroughs that will influence market growth. The detailed market research, industry sector growth and development, and new product introductions covered in this report on the Antiphospholipid Syndrome Market are of great assistance to the important new commercial players joining the market.
This Antiphospholipid Syndrome Market report research conducts a careful market evaluation and provides a professional analysis of the industry taking into account market development, present market circumstances, and forecasts for the future. The market driving factors, market overview, industry volume, and market share are also highlighted in this Antiphospholipid Syndrome Market report analysis.
Regions Covered in the Report-
- The United States
- EU5 (Germany, France, Italy, Spain, and the United Kingdom)
- Japan
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Antiphospholipid Syndrome: An Overview
Antiphospholipid antibody syndrome (commonly called antiphospholipid syndrome or APS) is an autoimmune disease which can cause frequent clotting in arteries and veins and/or miscarriages. The clotting results from the presence of proteins in the blood called anti-phospholipid autoantibodies (commonly called aPL) formed against the person’s own tissues.
Key highlights of the Antiphospholipid Syndrome Market Report
- According to a study conducted by García et. al. (2019), the annual estimated prevalence of antiphospholipid antibody syndrome was 50 (95% CI 42–58) per 100,000 population.
- According to a study by D’Cruz et. al. (2019), prevalence in the UK peaked at 50 (95% CI 49 – 55) in females in 2011 and 9.8 (95% CI 8.6 – 11.1) per 100,000 in males in 2012.
- According to a study by Radin et. al. (2020), the prevalence cases of Antiphospholipid antibody syndrome in Italy are 40-50 cases per 100,000 persons and the diagnosis rate of Antiphospholipid antibody syndrome in Italy were 63% in aged of ≤50 years, 39% ≤40 years, and 18% ≤30 years.
Antiphospholipid Syndrome Epidemiology Insights
According to American College of Rheumatology (2021) it was reported that antiphospholipid antibody syndrome affects women five times more commonly than men. For arterial events, recurrences are also prevented with drugs that inhibit platelets, such as aspirin and clopidogrel (Plavix) and for pregnancy related events subcutaneous injections of heparin and low-dose aspirin are the standard therapy for preventing miscarriages.
Antiphospholipid Syndrome Epidemiology Segmentation in the 7MM
- Total Prevalence Case
- Age-specific Cases
- Clinical Manifestations
- Gender-specific Cases
- Diagnosed and Treatable Cases
Antiphospholipid Syndrome Treatment Market
Currently, treatment of patients with Antiphospholipid syndrome is based on long-term oral anticoagulation therapy for thrombotic manifestations and the combination of low dose aspirin (LDA) and low-molecular-weight heparin (LMWH) to prevent obstetric manifestations. However, the lack of well-designed studies means that the strength of some recommendations is debatable. Innovative therapeutic approaches, such as immune modulation, complement inhibition, and targeting inflammation, are under study. Further mechanistic and clinical studies are needed to develop improved therapies for this potentially devastating illness. Better understanding of the pathophysiological mechanisms of Antiphospholipid syndrome will help to identify new therapeutic targets, and a balance between anticoagulation and immunomodulatory drugs for different Antiphospholipid syndrome manifestations.
Antiphospholipid Syndrome Market Insights
Low dose aspirin (LDA) and Low-molecular-weight heparin (LMWH) used in thrombotic Antiphospholipid syndrome women. Sometime LMWH is used with or without aspirin throughout pregnancy. LMWH acts through mechanisms alternative to its well-known anticoagulant effect, because of its ability to bind β2GPI. For those patients with purely obstetric APS and no prior thrombosis (OAPS), prophylactic dose LMWH and LDA until 6 weeks postpartum is recommended.
Antiphospholipid Syndrome Market Forecast
Reimbursement may be referred to as the negotiation of a price between a manufacturer and payer that allows the manufacturer access to the market. It is provided to reduce the high costs and make the essential drugs affordable. Health technology assessment (HTA) plays an important role in reimbursement decision-making and recommending the use of a drug. These recommendations vary widely throughout the seven major markets, even for the same drug.
Antiphospholipid Syndrome Market Drivers
- Increase in awareness
- Increase in R&D of diagnostic tools leads to better diagnosis of the disease
- Increasing Prevalence of the Disease
Antiphospholipid Syndrome Market Barriers
- Off-label drugs usage
- Lack of emerging therapies
- Lack of management of Disease
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Table of Content
- Key Insights
- Executive Summary
- Competitive Intelligence Analysis for Antiphospholipid Syndrome
- Antiphospholipid Syndrome Market Overview at a Glance
- Antiphospholipid Syndrome Disease Background and Overview
- Patient Journey
- Antiphospholipid Syndrome Epidemiology and Patient Population
- Treatment Algorithm, Current Treatment, and Medical Practices
- Antiphospholipid Syndrome Unmet Needs
- Key Endpoints of Antiphospholipid Syndrome Treatment
- Antiphospholipid Syndrome Marketed Products
- Antiphospholipid Syndrome Emerging Therapies
- Antiphospholipid Syndrome Seven Major Market Analysis
- Attribute analysis
- 7MM: Antiphospholipid Syndrome Market Outlook
- Access and Reimbursement Overview of Antiphospholipid Syndrome
- KOL Views
- Antiphospholipid Syndrome Market Drivers
- Antiphospholipid Syndrome Market Barriers
- Appendix
- DelveInsight Capabilities
- Disclaimer
- About DelveInsight
Antiphospholipid Syndrome Market Report Highlights
- In the coming years, the Antiphospholipid Syndrome market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
- The companies and academics are working to assess challenges and seek opportunities that could influence Antiphospholipid Syndrome R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition
- Major players are involved in developing therapies for Antiphospholipid Syndrome. The launch of emerging therapies will significantly impact the Antiphospholipid Syndrome market
- A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Antiphospholipid Syndrome
- Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities
Why should you buy this report?
- The report will help in developing business strategies by understanding trends shaping and driving the Antiphospholipid Syndrome market
- To understand the future market competition in the Antiphospholipid Syndrome market and Insightful review of the key market drivers and barriers
- Organize sales and marketing efforts by identifying the best opportunities for Antiphospholipid Syndrome in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom), and Japan
- Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
- Organize sales and marketing efforts by identifying the best opportunities for the Antiphospholipid Syndrome market
- To understand the future market competition in the Antiphospholipid Syndrome market
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