Argininosuccinic Aciduria Market Report gives readers a thorough assessment of key market drivers, restraints, prospects, opportunities, restraints, current trends, and technological and industrial breakthroughs that will influence market growth. The detailed market research, industry sector growth and development, and new product introductions covered in this report on the Argininosuccinic Aciduria Market are of great assistance to the important new commercial players joining the market.

 

This Argininosuccinic Aciduria Market report research conducts a careful market evaluation and provides a professional analysis of the industry taking into account market development, present market circumstances, and forecasts for the future. The market driving factors, market overview, industry volume, and market share are also highlighted in this Argininosuccinic Aciduria Market report analysis.

 

Regions Covered in the Report-

• The United States
• EU5 (Germany, France, Italy, Spain, and the United Kingdom)
• Japan

 

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Argininosuccinic Aciduria: An Overview

Argininosuccinic aciduria usually becomes evident in the first few days of life. An infant with Argininosuccinic aciduria may be lacking in energy (lethargic) or unwilling to eat, and have a poorly controlled breathing rate or body temperature. Some babies with this disorder experience seizures or unusual body movements, or go into a coma. Complications from argininosuccinic aciduria may include developmental delay and intellectual disability. Progressive liver damage, high blood pressure (hypertension), skin lesions, and brittle hair may also be seen.

 

Key highlights of the Argininosuccinic Aciduria Market Report

• Argininosuccinic aciduria is a rare disorder that affects fewer than a thousand people in the United States. It is estimated to affect anywhere between approximately one in 70,000 to 1 in 218,000 live births. Most cases of this condition are detected shortly after birth by newborn screening.
• Males and females are affected in equal numbers. Onset of symptoms usually occurs at birth, but may not be noticeable for days or weeks. In some children, onset of symptoms may not occur until later during infancy or childhood.
• The estimated frequency of urea cycle disorders collectively is approximately one in 30,000. However, because urea cycle disorders like argininosuccinic aciduria often go unrecognized, these disorders are under-diagnosed, making it difficult to determine their true frequency in the general population.

 

Argininosuccinic Aciduria Epidemiology Insights

 Inherited as an autosomal recessive trait, argininosuccinic aciduria affects both sexes equally. DelveInsight’s report provides the graphical analysis of the total Incident cases of Argininosuccinic Aciduria in the United States. DelveInsight has segmented the target patient pool based on diagnosed and treatable cases.

 

Argininosuccinic Aciduria Epidemiology Segmentation in the 7MM

• Incident Cases
• Age-specific Incident Cases
• Severity-specific Incident Cases
• Diagnosed and Treatable Cases

 

Argininosuccinic Aciduria Treatment Market

The treatment of argininosuccinic aciduria is aimed at preventing excessive ammonia from being formed or from removing excessive ammonia during a hyperammonemic episode. Long-term therapy combines dietary restrictions and the stimulation of alternative methods of converting and excreting nitrogen from the body (alternative pathways therapy).

 

Argininosuccinic Aciduria Market Insights

Immediate diagnosis and treatment of argininosuccinic academia in the neonatal period is critical to normal development and survival. Treatment is usually effective if started before ammonia levels are excessive. Hyperammonemia is a medical emergency that may require dialysis. Individuals should follow a life-long low-protein diet, which may require medical formulas and foods. Certain medications, such as sodium benzoate and/or sodium phenylacetate, as well as supplementation of arginine, may help prevent ammonia build-up. Episodes of high ammonia levels may require medications via IV or dialysis.

 

Argininosuccinic Aciduria Market Forecast

In individuals where there is no improvement or where hyperammonemic coma develops, the removal of wastes by filtering an affected individual’s blood through a machine (hemodialysis) may be necessary. Hemodialysis is also used to treat infants, children, and adults who are first diagnosed with argininosuccinic aciduria during hyperammonemic coma. In some individuals, a liver transplant may be recommended. This is an option of last resort for specific individuals who have progressive liver disease, experience recurrent medical crises and hospitalizations despite therapy, or who have a poor quality of life.

 

Argininosuccinic Aciduria Factors

The factors that shall expedite the growth of Argininosuccinic Aciduria market include increasing awareness about available treatments during the forecast period (2019–2030). Overall, the increasing Incidence, disease awareness, and promising emerging pipeline therapies will propel the market size forward during the forecast period. A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Argininosuccinic Aciduria.

 

Argininosuccinic Aciduria Market Size

The market size shall grow during the forecast period owing to the already launched therapies. The market size is expected to increase at a significant CAGR during the study period. Extensive R&D activities by academias and companies such as Takeda, ACER Therapeutics and others shall fuel the growth of the market during the forecast period, i.e., 2020–2030.

 

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Table of Content

1. Key Insights
2. Executive Summary
3. Competitive Intelligence Analysis for Argininosuccinic Aciduria
4. Argininosuccinic Aciduria Market Overview at a Glance
5. Argininosuccinic Aciduria Disease Background and Overview
6. Patient Journey
7. Argininosuccinic Aciduria Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Argininosuccinic Aciduria Unmet Needs
10. Key Endpoints of Argininosuccinic Aciduria Treatment
11. Argininosuccinic Aciduria Marketed Products
12. Argininosuccinic Aciduria Emerging Therapies
13. Argininosuccinic Aciduria Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Argininosuccinic Aciduria Market Outlook
16. Access and Reimbursement Overview of Argininosuccinic Aciduria
17. KOL Views
18. Argininosuccinic Aciduria Market Drivers
19. Argininosuccinic Aciduria Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

 

Argininosuccinic Aciduria Market Report Highlights

• In the coming years, the Argininosuccinic Aciduria market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
• The companies and academics are working to assess challenges and seek opportunities that could influence Argininosuccinic Aciduria R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition
• Major players are involved in developing therapies for Argininosuccinic Aciduria. The launch of emerging therapies will significantly impact the Argininosuccinic Aciduria market
• A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Argininosuccinic Aciduria
• Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities

 

Why should you buy this report?

• The report will help in developing business strategies by understanding trends shaping and driving the Argininosuccinic Aciduria market
• To understand the future market competition in the Argininosuccinic Aciduria market and Insightful review of the key market drivers and barriers
• Organize sales and marketing efforts by identifying the best opportunities for Argininosuccinic Aciduria in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom), and Japan
• Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
• Organize sales and marketing efforts by identifying the best opportunities for the Argininosuccinic Aciduria market
• To understand the future market competition in the Argininosuccinic Aciduria market

 

About Us

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