New York, Apr 29th, 2019 – Creative Biogene, a leading provider focusing on offering expertise support for gene discovery, regulation, and function, aiming to promote the development in pharmaceutical and biotechnology industry, recently release the launch of its whole selection of breast cancer cells, which help proceed the research related to breast cancer and support screening and diagnostic services to women in need.
Breast cancer is a complex disease caused by dysregulation of signaling networks caused by cytogenetic and epigenetic changes. An understanding of the pathways involved in the pathogenesis of breast cancer can help identify new targeted therapeutics, meanwhile, it can also be used for diagnosis and prognosis. There are several important risk factors for breast cancer, including null parity, older age, obesity, smoking and estrogen exposure. However, related research also showed that breast cancer patients have a strong genetic predisposition, such as patients with BRCA1 and BRCA2 gene mutations and patients with p53 mutations (Li-Fraumeni syndrome), STK11 (Peutz-Jeghers syndrome) and PTEN (Cowden syndrome) have a high risk of breast cancer.
Many signaling pathways are involved in the pathogenesis of breast cancer. Some important examples are the HER-2 tyrosine kinase pathway, the hedgehog signaling pathway, the PI3K pathway, the p53 pathway, and the PTEN pathway. Several cell growth receptor pathways have changed in breast cancer, including NGF, HGF, FGF and IGF, suggesting that many growth factors interact with breast cancer cells, leading to uncontrolled proliferation and survival advantages of cancer cells. The study also showed that many cytokines and inflammatory pathways in breast cancer have also changed, including TNF, NF-kB, TGF-β, iNOS, IL9 and IL15, suggesting that inflammation plays a crucial role in the development of breast cancer.
We are capable to offer a variety of breast cancer pathway related products for drug discovery program, including stable cell lines, viral particles and clones.
‘As a leading biotechnology company that strives to promote the diagnostics and treatment of disease, we are honored to help in the fight against breast cancer,” said Marcia Brady, the marketing director of Creative Biogene. ‘Whether it’s keeping people safe with personal security devices or providing support for preventative measures to combat breast cancer, it’s our long term mission to work for it.’
About Creative Biogene
Creative Biogene, the leading brand in biotechnology and pharmaceutical by consumers worldwide, is operated with over 10 years of experience. With innovative products and services, as well as in-house experts, Creative Biogene has become a well-recognized industry leader that supports the experiments in the areas of biological and biomedical for better performance and reliable results.
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Company Name: Creative Biogene
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Website: https://www.creative-biogene.com