DelveInsight’s Cholangiocarcinoma Market Insights report provides a thorough understanding of current treatment practices, emerging Cholangiocarcinoma market share of the individual therapies, current and forecasted Cholangiocarcinoma market size from 2018 to 2030 segmented into 7MM (the USA, EU5 (the UK, Italy, Spain, France, and Germany), and Japan).
Cholangiocarcinoma Overview
Cholangiocarcinoma (CCA) is a rare and heterogeneous malignant neoplasm with epithelial cell origin of the biliary duct and histologic and biochemical features of cholangiocyte differentiation. The major function of the bile duct is to move a fluid called bile from the liver and gallbladder to the small intestine, where it helps digest the fats in food. The causes of the abnormal proliferation in the bile ducts’ epithelial cells leading to tumors are unknown and most cases occur sporadically.
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Some of the key highlights of the Cholangiocarcinoma Market Report
- As per the assessments, in the 7MM, most of the patients with CCA were male.
- As per DelveInsight analysts, the total Cholangiocarcinoma incident population in the US was estimated to be 5,616 in 2020.
- Central necrosis or scarring is common and mucin may be visible on cut surfaces.
- Cholangiocarcinoma companies are included like incite Corporation, Roche, Delcath Systems, Basilea Pharmaceutical, Bayer, Loxo Oncology/Bayer, Zymeworks/BeiGene, Taiho Oncology, Merck/GlaxoSmithKline, Eisai, and many others.
- Cholangiocarcinoma drugs are included like Melphalan/HDS, Pemazyre (Pemigatinib), Rozlytrek (Entrectinib), Derazantinib, Regorafenib, Larotrectinib, ZW25, Futibatinib (TAS-120), and many others.
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Cholangiocarcinoma Classification
CCAs are classified into Intrahepatic and Extrahepatic. CCA which arise in the liver parenchyma beyond the second-order bile ducts, being categorized as intrahepatic form (I-CCA), or arise in the bile ducts outside the liver parenchyma, considered an extrahepatic form (E-CCA).
Cholangiocarcinoma Causes
The causes of the abnormal proliferation in the bile ducts’ epithelial cells leading to tumors are unknown and most cases occur sporadically. The malignant tumor may arise from any portion of the bile duct epithelium, i.e., anywhere from the terminal ductules (canals of Hering) to the ampulla of Vater, as well as at the peribiliary glands (intramural and extramural).
Cholangiocarcinoma Treatment
Treatments for cholangiocarcinoma (bile duct cancer) may include: Surgery, Liver transplant, Chemotherapy, Radiation therapy, Immunotherapy, and Many More. The commonly available modalities for the treatment of ICCA include surgery and radiation therapies for curative intent and systemic therapies, including chemotherapy and chemoradiotherapy, for the surgery of ineligible patients.
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Cholangiocarcinoma Emerging Therapy Assessment
Companies across the globe are diligently working toward the development of novel treatment therapies with a considerable amount of success over the years. Key players, such as Delcath Systems, Basilea Pharmaceutica, Agios Pharmaceuticals, Loxo Oncology and QED Therapeutics etc., are developing therapies for the treatment of CCA and its types.
Cholangiocarcinoma Market Drivers
- Rising Incidence
- Technological advancements in the identification of biomarkers
- Increasing R&D Activities
Cholangiocarcinoma Market Barriers
- Lack of awareness about the disease
- Heterogeneity of the disease
- Delayed Diagnosis
Cholangiocarcinoma Market Report Scope
- The report covers the descriptive overview of Cholangiocarcinoma (CCA), explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
- Comprehensive insight has been provided into the Cholangiocarcinoma (CCA) epidemiology and treatment in the 7MM
- Additionally, an all-inclusive account of both the current and emerging therapies for Cholangiocarcinoma (CCA) is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
- A detailed review of the Cholangiocarcinoma (CCA) market; historical and forecasted is included in the report, covering drug outreach in the 7MM
- The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Cholangiocarcinoma (CCA) market.
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Table of Content
1. Key Insights
2. Executive Summary of Cholangiocarcinoma (CCA)
3. Competitive Intelligence Analysis for Cholangiocarcinoma (CCA)
4. Cholangiocarcinoma (CCA): Market Overview at a Glance
5. Cholangiocarcinoma (CCA): Disease Background and Overview
6. Patient Journey
7. Cholangiocarcinoma (CCA) Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Cholangiocarcinoma (CCA) Unmet Needs
10. Key Endpoints of Cholangiocarcinoma (CCA) Treatment
11. Cholangiocarcinoma (CCA) Marketed Products
12. Cholangiocarcinoma (CCA) Emerging Therapies
13. Cholangiocarcinoma (CCA): Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Cholangiocarcinoma (CCA)
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
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