Global C-MET / HGF Inhibitors Market
WiseGuyRerports.com Presents Global C-MET / HGF Inhibitors Market Insights, Forecast to 2025” New Document to its Studies Database. The Report Contain 148 Pages With Detailed Analysis.
Description
c-Met is a proto-oncogene responsible for encoding the high-affinity receptor for hepatocyte growth factor (HGF). Hepatocyte growth factor is also known as scatter factor which participates in HGF/c-MET signaling pathway. This pathway plays vital role in mitogenesis and morphogenesis during embryonic development and wound healing. The controlled natural activity of c-Met and HGF is important in mammalian development, tissue maintenance, and repair. Binding of HGF to c-MET receptor induces several biological responses collectively known as invasive growth program. These responses are elicited due to activation of several pathways such as RAS pathway, PI3K pathway, STAT pathway, beta-catenin pathway and Notch pathway. However, dysregulation of the HGF/c-MET signaling pathway has been associated with the progression of cancers through activation of oncogenic pathways, angiogenesis and metastasis.
The major cancers such as breast, colon and non-small-cell lung carcinoma (NSCLC) are being examined for efficacy with c-MET / HGF inhibitors. Several small molecule c-Met kinase inhibitors have demonstrated clinical efficacy in cancer treatment and many clinical trials are underway. However, as the small molecule inhibitors lack specificity or selectivity they can cause toxicity. Therefore, researchers are increasing focus to develop antibody therapeutics against c-Met or HGF.
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The global C-MET / HGF Inhibitors market is valued at xx million US$ in 2018 and will reach xx million US$ by the end of 2025, growing at a CAGR of xx% during 2019-2025. The objectives of this study are to define, segment, and project the size of the C-MET / HGF Inhibitors market based on company, product type, end user and key regions.
This report studies the global market size of C-MET / HGF Inhibitors in key regions like North America, Europe, Asia Pacific, Central & South America and Middle East & Africa, focuses on the consumption of C-MET / HGF Inhibitors in these regions.
This research report categorizes the global C-MET / HGF Inhibitors market by top players/brands, region, type and end user. This report also studies the global C-MET / HGF Inhibitors market status, competition landscape, market share, growth rate, future trends, market drivers, opportunities and challenges, sales channels and distributors.
The following manufacturers are covered in this report, with sales, revenue, market share for each company:
Abxign
Abbott Laboratories
Amgen
ArQule
Astex Therapeutics
AVEO Pharmaceuticals
Bristol-Myers Squibb(BMS)
Chroma Therapeutics
Daiichi Sankyo
Deciphera Pharmaceuticals
Eisai
Eli Lilly
Exelixis
Genmab
Galaxy Biotech
GlaxoSmithKline(GSK)
Hutchison MediPharma
Johnson & Johnson
Kringle Pharmaceuticals
Merck
Methylgene
Novartis
Pfizer
ProMetic BioTherapeutics
Takeda Pharmaceutical
Market size by Product
C-Met Biologic Inhibitors
Small Molecule C-Met Inhibitors
HGF Antagonist Antibodies
C-Met Antagonist Antibodies(MetMAb)
HGF Kringle Variant Antagonists
Market size by End User
Hospital Pharmacies
Retail Pharmacies
Drug Stores
Online Sales
Market size by Region
North America
United States
Canada
Mexico
Asia-Pacific
China
India
Japan
South Korea
Australia
Indonesia
Singapore
Malaysia
Philippines
Thailand
Vietnam
Europe
Germany
France
UK
Italy
Spain
Russia
Central & South America
Brazil
Rest of Central & South America
Middle East & Africa
GCC Countries
Turkey
Egypt
South Africa
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Table of Contents -Major Key Points
1 Study Coverage
1.1 C-MET / HGF Inhibitors Product
1.2 Market Segments
1.3 Key Manufacturers Covered
1.4 Market by Type
1.4.1 Global C-MET / HGF Inhibitors Market Size Growth Rate by Product
1.4.2 C-Met Biologic Inhibitors
1.4.3 Small Molecule C-Met Inhibitors
1.4.4 HGF Antagonist Antibodies
1.4.5 C-Met Antagonist Antibodies(MetMAb)
1.4.6 HGF Kringle Variant Antagonists
1.5 Market by End User
1.5.1 Global C-MET / HGF Inhibitors Market Size Growth Rate by End User
1.5.2 Hospital Pharmacies
1.5.3 Retail Pharmacies
1.5.4 Drug Stores
1.5.5 Online Sales
1.6 Study Objectives
1.7 Years Considered
2 Executive Summary
2.1 Global C-MET / HGF Inhibitors Market Size
2.1.1 Global C-MET / HGF Inhibitors Revenue 2014-2025
2.1.2 Global C-MET / HGF Inhibitors Sales 2014-2025
2.2 C-MET / HGF Inhibitors Growth Rate by Regions
2.2.1 Global C-MET / HGF Inhibitors Sales by Regions
2.2.2 Global C-MET / HGF Inhibitors Revenue by Regions
…………
11 Company Profiles
11.1 Abxign
11.1.1 Abxign Company Details
11.1.2 Company Business Overview
11.1.3 Abxign C-MET / HGF Inhibitors Sales, Revenue and Gross Margin (2014-2019)
11.1.4 Abxign C-MET / HGF Inhibitors Products Offered
11.1.5 Abxign Recent Development
11.2 Abbott Laboratories
11.2.1 Abbott Laboratories Company Details
11.2.2 Company Business Overview
11.2.3 Abbott Laboratories C-MET / HGF Inhibitors Sales, Revenue and Gross Margin (2014-2019)
11.2.4 Abbott Laboratories C-MET / HGF Inhibitors Products Offered
11.2.5 Abbott Laboratories Recent Development
11.3 Amgen
11.3.1 Amgen Company Details
11.3.2 Company Business Overview
11.3.Amgen C-MET / HGF Inhibitors Sales, Revenue and Gross Margin (2014-2019)
11.3.4 Amgen C-MET / HGF Inhibitors Products Offered
11.3.5 Amgen Recent Development
11.4 ArQule
11.4.1 ArQule Company Details
11.4.2 Company Business Overview
11.4.3 ArQule C-MET / HGF Inhibitors Sales, Revenue and Gross Margin (2014-2019)
11.4.4 ArQule C-MET / HGF Inhibitors Products Offered
11.4.5 ArQule Recent Development
11.5 Astex Therapeutics
11.5.1 Astex Therapeutics Company Details
11.5.2 Company Business Overview
11.5.3 Astex Therapeutics C-MET / HGF Inhibitors Sales, Revenue and Gross Margin (2014-2019)
11.5.4 Astex Therapeutics C-MET / HGF Inhibitors Products Offered
11.5.5 Astex Therapeutics Recent Development
11.6 AVEO Pharmaceuticals
11.6.1 AVEO Pharmaceuticals Company Details
11.6.2 Company Business Overview
11.6.3 AVEO Pharmaceuticals C-MET / HGF Inhibitors Sales, Revenue and Gross Margin (2014-2019)
11.6.4 AVEO Pharmaceuticals C-MET / HGF Inhibitors Products Offered
11.6.5 AVEO Pharmaceuticals Recent Development
……..CONTINUED
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