DelveInsight’s Cone rod dystrophy Market Insights report provides a thorough understanding of current treatment practices, emerging drugs, Cone rod dystrophy market share of the individual therapies, current and forecasted Cone rod dystrophy market size from 2019 to 2032 segmented into 7MM (the USA, EU5 (the UK, Italy, Spain, France, and Germany), and Japan).
Cone Rod Dystrophy Overview
Cone rod dystrophies (CRDs) are inherited retinal dystrophies that belong to the group of pigmentary retinopathies. CRDs are characterized by retinal pigment deposits visible on fundus examination, predominantly localized to the macular region. CRD is characterized by primary cone involvement, or, sometimes, by concomitant loss of both cones and rods that explains the predominant symptoms of CRDs.
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Some of the key highlights of the cone-rod dystrophy market report
- CRD is estimated to affect 1 in 30,000 to 40,000 individuals.
- Cone dystrophy affects males and females in equal numbers when it occurs sporadically or is inherited in an autosomal dominant or recessive pattern. The X-linked form of cone dystrophy only affects males fully, although some females may have mild symptoms of the disorder.
- Inherited disorders of cone function are classically divided into two subtypes: stationary and progressive. Mutations in 32 genes are reported to cause CRD, among which 6 identified genes are predominantly cause CRD and 22 that lead to CRD.
- Cone rod dystrophy key playersincluded such as MeiraGTx, Applied Genetic Technologies Corp, and several others.
- Cone rod dystrophy therapies included such as AAV8-RPGR, AGTC-501, and several others.
Cone Rod Dystrophy Symptoms
Initial signs and symptoms that usually occur in childhood may include decreased sharpness of vision (visual acuity) and abnormal sensitivity to light (photophobia). These signs are usually followed by blind spots in the central field of vision (scotomas), loss of color perception, and loss of peripheral vision. Most individuals with this condition are legally blind by mid adulthood.
Cone Rod Dystrophy Forms
There are two main forms of cone dystrophy: stationary cone dystrophy and progressive cone dystrophy. In stationary cone dystrophy, symptoms tend to remain stable and are usually present at birth or early childhood. In progressive cone dystrophy, symptoms slowly worsen over time.
Cone Rod Dystrophy Types
There are more than 30 types of cone-rod dystrophy, which are distinguished by their genetic cause and their pattern of inheritance: autosomal recessive, autosomal dominant, and X-linked. Additionally, cone-rod dystrophy can occur alone without any other signs and symptoms or it can occur as part of a syndrome that affects multiple parts of the body.
Cone Rod Dystrophy Epidemiology Segmentation
- Total prevalent cases
- Inheritance-specific cases
- Type-specific cases
- Diagnosed and treatable cases
Cone Rod Dystrophy Treatment Market
With no proven treatments for Cone rod dystrophies (CRD) that halt progression or restore lost vision, the management of CRD aims at slowing down the degenerative process, treating the complications and helping patients to cope with the social and psychological impact of blindness and consists of symptomatic alleviation, including refractive correction, use of tinted spectacles/contact lenses for photophobia and low vision aids.
Cone Rod Dystrophy Market Insights
Some ophthalmologists believe that treatment with high doses of Vitamin A can slow the progression. Patients with specific forms of CRDs can be advised to adopt strategies to try to slow degeneration, based on the knowledge of gene function or investigation of animal models. The dynamics of the Cone rod dystrophie’s market are anticipated to change in the coming years owing to the improvement in the rise in the number of healthcare spending across the world. There are some positive candidates in the early, middle and late developmental stages.
Cone Rod Dystrophy Emerging Therapy Assessment
Key players, such as MeiraGTx, Applied Genetic Technologies Corp, and others are in the process of developing potential therapies for the treatment of Cone Dystrophy. The launch of emerging therapies is expected to significantly impact the treatment scenario of Cone rod dystrophies in the upcoming years.
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Table of content
1. Key Insights
2. Executive Summary of Cone Rod Dystrophy
3. Competitive Intelligence Analysis for Cone Rod Dystrophy
4. Cone Rod Dystrophy: Market Overview at a Glance
5. Cone Rod Dystrophy: Disease Background and Overview
6. Patient Journey
7. Cone Rod Dystrophy Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Cone Rod Dystrophy Unmet Needs
10. Key Endpoints of Cone Rod Dystrophy Treatment
11. Cone Rod Dystrophy Marketed Products
12. Cone Rod Dystrophy Emerging Therapies
13. Cone Rod Dystrophy: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Cone Rod Dystrophy
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
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