“Epidermolysis Bullosa Pipeline Insight, 2024“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Epidermolysis Bullosa Market.

The Epidermolysis Bullosa Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the Epidermolysis Bullosa Pipeline Report:

• Companies across the globe are diligently working toward developing novel Epidermolysis Bullosa treatment therapies with a considerable amount of success over the years. Epidermolysis Bullosa Key players such as – Berg Pharma, Holostem Terapie Avanzate, Aegle Therapeutics, RegeneRx Biopharmaceuticals, BridgeBio Pharma, InMed Pharmaceuticals, Fibrocell Science, Krystal Biotech, and others, are developing therapies for the Epidermolysis Bullosa treatment 

• Epidermolysis Bullosa Emerging therapies such as – BPM31510, HOLOGENE-17,AGLE102, RGN-137, PTR-01, INM-755, Dabocemagene autoficel, VYJUVEK, and others are expected to have a significant impact on the Epidermolysis Bullosa market in the coming years.   

• In Spetember 2024, In a small real-world study, treatment with Janus kinase (JAK) inhibitors, including upadacitinib and baricitinib, demonstrated greater effectiveness than dupilumab in alleviating itching and skin lesions in individuals with epidermolysis bullosa pruriginosa (EBP). Among five patients on dupilumab, only two achieved a 50% reduction in itching, with none experiencing total relief. In comparison, all five patients treated with JAK inhibitors who had measurable itch scores reported complete relief from itching.

• In December 2023, The FDA has authorized the use of birch triterpenes (Filsuvez, Chiesi Global Rare Diseases) topical gel for the treatment of partial thickness wounds associated with junctional and dystrophic epidermolysis bullosa (EB). Chiesi Global Rare Diseases also affirmed that this new medication stands as the sole FDA-approved option for patients diagnosed with junctional Epidermolysis Bullosa. The FDA’s decision was grounded on findings from the phase 3 EASE trial (Identifier: NCT03068780), which involved 223 participants across 58 sites in 28 countries. The trial encompassed a three-month double-blind, randomized controlled phase followed by a 24-month open-label, single-arm phase.

Epidermolysis Bullosa Overview

Epidermolysis bullosa (EB) is a rare genetic disorder characterized by extremely fragile skin that is prone to blistering and tearing from minor friction or trauma. It is caused by mutations in genes responsible for producing proteins that help to anchor the layers of the skin together. As a result, individuals with EB experience painful blisters and sores on their skin, as well as in the mucous membranes lining the mouth, esophagus, and other organs.

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Epidermolysis Bullosa Pipeline Therapeutics Assessment

• Epidermolysis Bullosa Assessment by Product Type

• Epidermolysis Bullosa By Stage and Product Type

• Epidermolysis Bullosa Assessment by Route of Administration

• Epidermolysis Bullosa By Stage and Route of Administration

• Epidermolysis Bullosa Assessment by Molecule Type

• Epidermolysis Bullosa by Stage and Molecule Type

DelveInsight’s Epidermolysis Bullosa Report covers around 21+ products under different phases of clinical development like

• Late-stage products (Phase III)

• Mid-stage products (Phase II)

• Early-stage product (Phase I)

• Pre-clinical and Discovery stage candidates

• Discontinued & Inactive candidates

• Route of Administration

Further Epidermolysis Bullosa product details are provided in the report. Download the Epidermolysis Bullosa pipeline report to learn more about the emerging Epidermolysis Bullosa therapies 

Emerging Epidermolysis Bullosa Drugs Under Different Phases of Clinical Development Include:

• BPM31510: Berg Pharma

• HOLOGENE-17: Holostem Terapie Avanzate

• AGLE102: Aegle Therapeutics

• RGN-137: RegeneRx Biopharmaceuticals

• PTR-01: BridgeBio Pharma

• INM-755: InMed Pharmaceuticals

• Dabocemagene autoficel: Fibrocell Science

• VYJUVEK: Krystal Biotech

Epidermolysis Bullosa Pipeline Analysis:

The Epidermolysis Bullosa pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the Epidermolysis Bullosa treatment with aggregate therapies developed by each company for the same.

• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Epidermolysis Bullosa Treatment.

• Epidermolysis Bullosa key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

• Epidermolysis Bullosa Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 

• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Epidermolysis Bullosa market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

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Epidermolysis Bullosa Pipeline Market Drivers

• Improving Healthcare Infrastructure

• Demand for New and Effective Drugs

Epidermolysis Bullosa Pipeline Market Barriers

• Currently no cure for all types of Epidermolysis Bullosa (DEB)

• Making a diagnosis for a genetic or rare disease is often challenging

Scope of Epidermolysis Bullosa Pipeline Drug Insight    

• Coverage: Global

• Key Epidermolysis Bullosa Companies: Berg Pharma, Holostem Terapie Avanzate, Aegle Therapeutics, RegeneRx Biopharmaceuticals, BridgeBio Pharma, InMed Pharmaceuticals, Fibrocell Science, Krystal Biotech, and others

• Key Epidermolysis Bullosa Therapies: BPM31510, HOLOGENE-17,AGLE102, RGN-137, PTR-01, INM-755, Dabocemagene autoficel, VYJUVEK, and others

• Epidermolysis Bullosa Therapeutic Assessment: Epidermolysis Bullosa current marketed and Epidermolysis Bullosa emerging therapies

• Epidermolysis Bullosa Market Dynamics:  Epidermolysis Bullosa market drivers and Epidermolysis Bullosa market barriers 

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About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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