Exomes Clinical Trials and Studies 2025: EMA, PDMA, FDA Approvals, Mechanism of Action, ROA, NDA, IND, and Companies by DelveInsight

Exomes Clinical Trials and Studies 2025: EMA, PDMA, FDA Approvals, Mechanism of Action, ROA, NDA, IND, and Companies by DelveInsight

DelveInsight’s, “Exomes Pipeline Insight” report provides comprehensive insights about 80+ companies and 100+ pipeline drugs in Exomes pipeline landscape. It covers the Exomes pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Exomes therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

 

Stay ahead with the latest insights! Download DelveInsight’s comprehensive Exomes Pipeline Report to explore emerging therapies, key Exomes Companies, and future Exomes treatment landscapes @ Exomes Pipeline Outlook Report

 

Key Takeaways from the Exomes Pipeline Report

  • DelveInsight’s Exomes pipeline report depicts a robust space with 80+ active players working to develop 100+ pipeline therapies for Exomes treatment.
  • The leading Exomes Companies such as Celularity, EVerZom, Direct Biologics, Cambium Bio, Capricor Therapeutics, Aegle Therapeutics, Organicell, Evecxia, ArunaBio, Evox, Coya Therapeutics, ILIAS Biologics, EV Therapeutics, Nano24 andothers.
  • Promising Exomes Therapies such as CAP-1002, EXO-CD24, AGLE-102, Progenza, EV-101, andothers.

 

Discover how the Exomes treatment paradigm is evolving. Access DelveInsight’s in-depth Exomes Pipeline Analysis for a closer look at promising breakthroughs @ Exomes Clinical Trials and Studies

 

Exomes Emerging Drugs Profile

  • CAP-1002: Capricor Therapeutics

Capricor’s (CAP-1002) is based on cardiosphere-derived cells, or CDCs, a cardiac-derived cell therapy that was first identified in the academic laboratory of Capricor’s scientific founder, Dr. Eduardo Marbán. CDCs have been the subject of over 100 peer-reviewed scientific publications and have been administered to over 200 human subjects across several clinical trials. CAP-1002 contains cardiosphere-derived cells, a type of heart cell progenitor, or precursor cell, that secretes tiny vesicles called exosomes. These exosomes then modulate the activity of the immune system and stimulate cellular regeneration. It is being investigated for its potential to modify the immune system’s activity to encourage cellular regeneration.

 

  • EXO-CD24: Nano24

EXO-CD24 (CovenD24), is an investigational drug being developed by Nano24. The company has developed a new anti-inflammatory drug, EXO-CD24, a combination of an immune checkpoint (CD24) and a delivery platform (exosomes). CD24 inhibits the NF-kB pathway and the production of cytokines/chemokines. EXO-CD24 discriminates damage-from pathogen-associated molecular patterns (DAMPs and PAMPs) therefore does not interfere with viral clearance. EXO-CD24 was produced and purified from CD24-expressing 293-TREx™ cells. Exosomes displaying murine CD24 (mCD24) were also created.

 

  • AGLE-102: Aegle Therapeutics

AGLE 102 is an allogeneic derived extracellular vesicle (EV) product derived from normal donor mesenchymal stem cells (MSCs). AGLE-102 is a composite of mesenchymal stem cell-derived extracellular vesicles that deliver proteins, genetic material and regenerative healing factors to diseased and damaged tissue. The drug is being developed in the Phase I/II stage of its development for the treatment of Burns and Epidermolysis bullosa dystrophica. The drug is also in the preclinical stage of its development for the Graft vs. Host Disease.

 

  • Progenza: Cambium Bio

Progenza is an off-the-shelf allogeneic stem cell product with the first targeted treatment being for knee osteoarthritis. The product is produced from mesenchymal stem cells (MSCs) from adipose (fat) tissue from a healthy donor who has been extensively screened. Progenza includes secretions from donor MSCs that improves viability and functionality of the cells after freezing.

 

  • EV-101: EV Therapeutics

EV Therapeutics is a pre-clinical stage immuno-oncology biotechnology company devoted to developing first-in-class therapies based on modified tumor extracellular vesicles (mTEVs) to significantly transform cancer therapy and other unmet medical needs that are addressable with its proprietary technology platform. The leading candidate EV101, has demonstrated pre-clinical efficacy across solid tumor and advanced metastatic animal models both as a monotherapy and combination therapy with checkpoint inhibitors.

 

Get a detailed analysis of the latest innovations in the Exomes pipeline. Explore DelveInsight’s expert-driven report today! @ Exomes Unmet Needs

 

Exomes Companies

Celularity, EVerZom, Direct Biologics, Cambium Bio, Capricor Therapeutics, Aegle Therapeutics, Organicell, Evecxia, ArunaBio, Evox, Coya Therapeutics, ILIAS Biologics, EV Therapeutics, Nano24 and others.

 

Exomes pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Intra-articular
  • Intraocular
  • Intrathecal
  • Intravenous
  • Oral
  • Parenteral
  • Subcutaneous
  • Topical
  • Transdermal

 

Exomes Products have been categorized under various Molecule types such as

  • Oligonucleotide
  • Peptide
  • Small molecule

 

Download DelveInsight’s latest report to gain strategic insights into upcoming therapies and key developments @ Exomes Market Drivers and Barriers, and Future Perspectives

 

Scope of the Exomes Pipeline Report

  • Coverage- Global
  • Exomes Companies- Celularity, EVerZom, Direct Biologics, Cambium Bio, Capricor Therapeutics, Aegle Therapeutics, Organicell, Evecxia, ArunaBio, Evox, Coya Therapeutics, ILIAS Biologics, EV Therapeutics, Nano24 and others.
  • Exomes Therapies- CAP-1002, EXO-CD24, AGLE-102, Progenza, EV-101, and others.
  • Exomes Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
  • Exomes Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

 

Which companies are leading the race in Exomes drug development? Find out in DelveInsight’s exclusive Exomes Pipeline Report—access it now! @ Exomes Emerging Drugs and Major Companies

 

Table of Content

  1. Introduction
  2. Executive Summary
  3. Exosomes: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. Exosomes – DelveInsight’s Analytical Perspective
  7. Late Stage Products (Phase III)
  8. CAP-1002: Capricor Therapeutics
  9. Drug profiles in the detailed report…..
  10. Mid Stage Products (Phase II)
  11. EXO-CD24: Nano24
  12. Drug profiles in the detailed report…..
  13. Early Stage Products (Phase I)
  14. Progenza: Cambium Bio
  15. Drug profiles in the detailed report…..
  16. Preclinical and Discovery Stage Products
  17. EV-101: EV Therapeutics
  18. Drug profiles in the detailed report…..
  19. Inactive Products
  20. Exosomes Key Companies
  21. Exosomes Key Products
  22. Exosomes – Unmet Needs
  23. Exosomes – Market Drivers and Barriers
  24. Exosomes – Future Perspectives and Conclusion
  25. Exosomes Analyst Views
  26. Exosomes Key Companies
  27. Appendix

 

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

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