Focal segmental glomerulosclerosis (FSGS) is a well-defined histologic pattern of injury characterized by sclerosis, hyalinosis, foam-cell infiltration, vacuolization of podocytes, and podocyte precursor proliferation between glomeruli tuft and Bowman’s capsule. It is “focal” in that only some glomeruli are affected and “segmental” where only a portion of the affected glomerulus is sclerosed. FSGS may be found either as primary or secondary forms. Primary FSGS sometimes has no identifiable cause or known etiology and linked to genetic mutations in podocyte-specific proteins, while secondary FSGS might include familial/genetic forms, virus-associated forms, drug-induced forms, and forms mediated by adaptive structural-functional response. The clinical features of FSGS include peripheral edema, marked proteinuria, hypertension, hypoalbuminemia, hyperlipidemia, and progressive loss of renal function. The pathogenesis of FSGS is very complex, mostly podocyte injury and parietal epithelial cells lining Bowman’s capsule play a central role in the disease progression. FSGS is classified as collapsing, tip, cellular, perihilar, and not otherwise specified variants according to the location and character of the sclerotic lesion (Columbia Classification).

 

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1. Age plays important role in the prevalence of FSGS. As per DelveInsight estimates, there were 4,306 cases of children with FSGS, while adults contribute 8,613 cases of FSGS in 2017 for Germany.

 

2. In 2017, there were 45,852 prevalent cases of FSGS in males and 34,731 cases in females and as per analyst assessments, the overall cases of FSGS in both the genders is subjected to increase in the coming years in 7MM.

 

3. Among the European 5 countries, the Germany had highest prevalent population of FSGS with 21,532 cases, followed by France. On the other hand, Spain had the lowest prevalent population of Focal Segmental Glomerulosclerosis.

 

 

 

 

 

 

 

1. Key Insights

2. Executive Summary of Focal Segmental Glomerulosclerosis (FSGS)

3. Competitive Intelligence Analysis for Focal Segmental Glomerulosclerosis (FSGS)

4. Focal Segmental Glomerulosclerosis (FSGS): Market Overview at a Glance

4.1. Focal Segmental Glomerulosclerosis (FSGS) Total Market Share (%) Distribution in 2017

4.2. Focal Segmental Glomerulosclerosis (FSGS) Total Market Share (%) Distribution in 2030

5. Focal Segmental Glomerulosclerosis (FSGS): Disease Background and Overview

6. Patient Journey

7. Focal Segmental Glomerulosclerosis (FSGS) Epidemiology and Patient Population

8. Treatment Algorithm, Current Treatment, and Medical Practices

8.1. Focal Segmental Glomerulosclerosis (FSGS) Treatment and Management

8.2. Focal Segmental Glomerulosclerosis (FSGS) Treatment Algorithm 

9. Unmet Needs

10. Key Endpoints of Focal Segmental Glomerulosclerosis (FSGS) Treatment

11. Marketed Products

12. Emerging Therapies

13. Focal Segmental Glomerulosclerosis (FSGS): Seven Major Market Analysis

13.1. Key Findings

13.2. Focal Segmental Glomerulosclerosis (FSGS) Market Size in 7MM

13.3. Focal Segmental Glomerulosclerosis (FSGS) Market Size by Therapies in the 7MM

14. Attribute analysis

15. 7MM: Market Outlook

16. Access and Reimbursement Overview of Focal Segmental Glomerulosclerosis (FSGS)

17. KOL Views

18. Market Drivers

19. Market Barriers

20. Appendix

20.1. Bibliography

20.2. Report Methodology

21. DelveInsight Capabilities

22. Disclaimer

23. About DelveInsight

Why should you buy this report?

• The report will help in developing business strategies by understanding trends shaping and driving the Focal Segmental Glomerulosclerosis (FSGS) market
• To understand the future market competition in the Focal Segmental Glomerulosclerosis (FSGS) market and Insightful review of the key market drivers and barriers
• Organize sales and marketing efforts by identifying the best opportunities for Focal Segmental Glomerulosclerosis (FSGS) in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
• Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
• Organize sales and marketing efforts by identifying the best opportunities for Focal Segmental Glomerulosclerosis (FSGS) market
• To understand the future market competition in the Focal Segmental Glomerulosclerosis (FSGS) market.

Related Reports:-

1. Focal Segmental Glomerulosclerosis (FSGS) – Epidemiology Forecast to 2030

2. Focal Segmental Glomerulosclerosis (FSGS) – Pipeline Insights, 2020