Genome Editing Market size was valued at USD 8.99 billion in 2023 to USD 31.15 billion by 2031, growing at a CAGR of 16.80% during the forecast period (2024-2031). In recent times, the popularity for genome editing is increasing rapidly due to the success in preclinical model and increasing competition among market players for business development. The technological innovations in gene editing technologies and increasing adoption in agricultural biotechnology is also further fueling the market growth. The gene editing technology clustered regularly short palindromic repeats (CRISPR) is an immensely advanced technology is biotechnology. The CRISPR uses bacterial immune system for either kill the genes or insert new genes. Now, the conventional genome editing processes are only partly capable of keeping pace with the constantly evolving genome modification era because they are time-consuming, inefficient, and labour-intensive in nature. Furthermore, the technology also offers transformative outcomes in different fields like plant, animal, & cell line genetic engineering and drug development & monitoring. The technology can analyze various gene combination, control gene expressi0on, and find the role of unique DNA bases.
Crop genetics has also been immensely influenced by developments in genomics and concerned technologies. Genomes and transcriptomes can be utilized for several crops. There are many advantages of gene manipulation tools in agricultural sectors like advancement of genetically modified plants or crops that has several advanced characteristics. They also help conserve biodiversity, minimize agricultural eco-footprint, reduce climate change, and help in eradicating poverty & hunger.
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Advancement in Genome Editing to Improve Diagnostic Tool for Oncology
The recent advancements in this area have significantly improved genome editing capabilities, allowing the change of interesting gene sequences in several cell types and model species. Genome engineering has evolved into a potentially game-changing diagnostic tool for oncology studies. Huge research organizations, such as government and academic research institutions, used genome engineering. The rapid advancement of gene editing technology is the main force behind this radical shift away from academics and toward clinical and diagnostic laboratories.
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Growing Use of Gene Editing to Cure Chronic Viral Diseases
Gene editing can correct or replace mutated genes responsible for monogenic diseases. This offers the potential to cure conditions like sickle cell anemia, cystic fibrosis, and certain types of muscular dystrophy. Gene editing can engineer immune cells to target and eliminate viral infections like HIV. This approach offers a potential cure for chronic viral diseases requiring lifelong management. Gene editing can facilitate the development of advanced gene therapies, where genes are added or modified to treat infections. This includes introducing therapeutic genes into patients’ cells to produce missing proteins or correct dysfunctional pathways. The growth of healthcare and therapeutic applications will stimulate increased investment in research and development for gene editing technologies, likely leading to improved tools, techniques, and safety protocols, further accelerating the field’s progress.
This Market Consist of the Following Segments:
Technology
(CRISPR)/Cas9,
TALENs/MegaTALs
ZFN, Meganuclease
Others
Delivery Method
Ex-vivo
In-Vivo
Application
Genetic Engineering [Cell Line Engineering, Animal Genetic Engineering, Plant Genetic Engineering, Others]
Clinical Applications [Diagnostics, Therapy Development]
Mode
Contract
In-house
End Use
Biotechnology and Pharmaceutical Companies
Academic and Government Research Institutes
Contract Research Organizations
Key Players Operating in Genome Editing Market
Merck KGaA (Germany)
Cibus Inc (US)
Recombinetics (US)
Sangamo Therapeutics (US)
Editas Medicine (US)
Precision BioSciences (US)
CRISPR Therapeutics (Switzerland)
Intellia Therapeutics, Inc (US)
Caribou Biosciences, Inc. (US)
Cellectis S.A (France)
AstraZeneca (UK)
Takara Bio Inc. (Japan)
Horizon Discovery Ltd. (Revvity, Inc.) (UK)
Danaher Corporation (US)
Transposagen Biopharmaceuticals, Inc. (US)
Genscript Biotech Corp (China)
New England Biolabs (US)
OriGene Technologies, Inc. (US)
bluebird bio, Inc (US)
Lonza (Switzerland)
Thermo Fisher Scientific Inc. (US)
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Increasing R&D for Development of New Drugs to Treat Rare Diseases
The search for new drugs has become more prevalent as medical understanding of illness mechanisms has enhanced. The advancement of novel pharmaceuticals has been increased by gene editing in developing disease models for testing. The transport of gene editing tools into cells has been enhanced because of viral vector technology developments. For gene therapies to be successful, this is extremely important. The development of gene editing applications has been fueled by medical discoveries that have produced safer and more efficient viral vectors. Treatment for rare diseases, sometimes known as orphan diseases, has also increased its popularity because of medical advancements.
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