“Geographic Atrophy Pipeline Insight, 2023“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Geographic Atrophy Market.

The Geographic Atrophy Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the Geographic Atrophy Pipeline Report:

• Companies across the globe are diligently working toward developing novel Geographic Atrophy treatment therapies with a considerable amount of success over the years. 
• Geographic Atrophy companies working in the treatment market are Complement Therapeutics, Apellis Pharmaceuticals, Nanoscope Therapeutics, ONL Therapeutics, NGM Biopharmaceuticals, Annexon, Genentech, Belite Bio, Inc, Aviceda Therapeutics, Iveric Bio, Alkeus Pharmaceuticals, Allegro Ophthalmics, Stealth BioTherapeutics, Novartis, Perceive Biotherapeutics, Inc., Genentech, Inc., NGM Biopharmaceuticals, Inc, Annexon, Inc., and others, are developing therapies for the Geographic Atrophy treatment 

• Emerging Geographic Atrophy therapies in the different phases of clinical trials are- CTx001, APL-2006, MCO 020, ONL 1204, NGM621, ANX 007, OpRegen, Tinlarebant, AVD-104, Zimura (avacincaptad pegol), ALK-001, Risuteganib, Elamipretide, PPY988, VOY-101, OpRegen, NGM621, ANX007, and others are expected to have a significant impact on the Geographic Atrophy market in the coming years.   
• In February 2023, The US FDA has approved the New Drug Application (NDA) for Zimura intended for treating geographic atrophy, and has also given it priority review status. The Prescription Drug User Fee Act (PDUFA) goal date for Zimura is set for August 19, 2023.
• In February 2022, NGM Biopharmaceuticals, Inc. revealed that the US Food and Drug Administration (FDA) has provided Fast Track designation to NGM621. NGM621 is a monoclonal antibody product designed to effectively block complement C3, aimed at treating individuals with geographic atrophy (GA) related to age-related macular degeneration.
• In November 2022, NGM Biopharmaceuticals, Inc. revealed the unveiling of results from additional analyses conducted after the fact of its randomized, double-masked, sham-controlled CATALINA Phase II trial, which explored NGM621. NGM621 is a monoclonal antibody specifically developed to impede the activity of complement component 3 (C3) among patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD). These findings were presented at The Retina Society Annual Scientific Meeting.

Geographic Atrophy Overview

Geographic Atrophy (GA), alternatively termed atrophic age-related macular degeneration (AMD) or advanced Dry AMD, represents an advanced stage of age-related macular degeneration. It involves a gradual and permanent deterioration of the retina (involving photoreceptors, retinal pigment epithelium, choriocapillaris), resulting in a gradual decline in visual capabilities. GA is a persistent condition leading to progressive visual function impairment over time.

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Emerging Geographic Atrophy Drugs Under Different Phases of Clinical Development Include:

• CTx001: Complement Therapeutics
• APL-2006: Apellis Pharmaceuticals
• MCO 020: Nanoscope Therapeutics
• ONL 1204: ONL Therapeutics
• NGM621: NGM Biopharmaceuticals
• ANX 007: Annexon
• OpRegen: Genentech
• Tinlarebant: Belite Bio, Inc
• AVD-104: Aviceda Therapeutics
• Zimura (avacincaptad pegol): Iveric Bio
• ALK-001: Alkeus Pharmaceuticals
• Risuteganib: Allegro Ophthalmics
• Elamipretide: Stealth BioTherapeutics
• PPY988: Novartis
• VOY-101: Perceive Biotherapeutics, Inc.
• OpRegen: Genentech, Inc.
• NGM621: NGM Biopharmaceuticals, Inc
• ANX007: Annexon, Inc.

Geographic Atrophy Route of Administration

Geographic Atrophy pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

• Oral
• Parenteral
• Intravitreal
• Subretinal
• Topical.

Geographic Atrophy Molecule Type

Geographic Atrophy Products have been categorized under various Molecule types, such as

• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy 

Geographic Atrophy Pipeline Therapeutics Assessment

• Geographic Atrophy Assessment by Product Type
• Geographic Atrophy By Stage and Product Type
• Geographic Atrophy Assessment by Route of Administration
• Geographic Atrophy By Stage and Route of Administration
• Geographic Atrophy Assessment by Molecule Type
• Geographic Atrophy by Stage and Molecule Type

DelveInsight’s Geographic Atrophy Report covers around 25+ products under different phases of clinical development like

• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Geographic Atrophy product details are provided in the report. Download the Geographic Atrophy pipeline report to learn more about the emerging Geographic Atrophy therapies

Some of the key companies in the Geographic Atrophy Therapeutics Market include:

Key companies developing therapies for Geographic Atrophy are – Annexon, Inc., Regenerative Patch Technologies, LLC, Apellis Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., Astellas Pharma Inc, Aviceda Therapeutics, Iveric Bio, Alkeus Pharmaceuticals, Allegro Ophthalmics, Stealth BioTherapeutics, Novartis, Perceive Biotherapeutics, Inc., Genentech, Inc., NGM Biopharmaceuticals, Inc, Gyroscope Therapeutics Limited, and others.

Geographic Atrophy Pipeline Analysis:

The Geographic Atrophy pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the treatment of Geographic Atrophy with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Geographic Atrophy Treatment.
• Geographic Atrophy key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Geographic Atrophy Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Geographic Atrophy market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about Geographic Atrophy drugs and therapies

Geographic Atrophy Pipeline Market Drivers

• Increase in Patient Burden, development of Novel Treatments are some of the important factors that are fueling the Geographic Atrophy Market.

Geographic Atrophy Pipeline Market Barriers

• However, high Cost of Treatment, side-effects associated with the disease and other factors are creating obstacles in the Geographic Atrophy Market growth.

Scope of Geographic Atrophy Pipeline Drug Insight    

• Coverage: Global
• Key Geographic Atrophy Companies: Complement Therapeutics, Apellis Pharmaceuticals, Nanoscope Therapeutics, ONL Therapeutics, NGM Biopharmaceuticals, Annexon, Genentech, Belite Bio, Inc, Aviceda Therapeutics, Iveric Bio, Alkeus Pharmaceuticals, Allegro Ophthalmics, Stealth BioTherapeutics, Novartis, Perceive Biotherapeutics, Inc., Genentech, Inc., NGM Biopharmaceuticals, Inc, Annexon, Inc., and others
• Key Geographic Atrophy Therapies: CTx001, APL-2006, MCO 020, ONL 1204, NGM621, ANX 007, OpRegen, Tinlarebant, AVD-104, Zimura (avacincaptad pegol), ALK-001, Risuteganib, Elamipretide, PPY988, VOY-101, OpRegen, NGM621, ANX007, and others
• Geographic Atrophy Therapeutic Assessment: Geographic Atrophy current marketed and Geographic Atrophy emerging therapies
• Geographic Atrophy Market Dynamics: Geographic Atrophy market drivers and Geographic Atrophy market barriers 

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Table of Contents

1. Geographic Atrophy Report Introduction

2. Geographic Atrophy Executive Summary

3. Geographic Atrophy Overview

4. Geographic Atrophy- Analytical Perspective In-depth Commercial Assessment

5. Geographic Atrophy Pipeline Therapeutics

6. Geographic Atrophy Late Stage Products (Phase II/III)

7. Geographic Atrophy Mid Stage Products (Phase II)

8. Geographic Atrophy Early Stage Products (Phase I)

9. Geographic Atrophy Preclinical Stage Products

10. Geographic Atrophy Therapeutics Assessment

11. Geographic Atrophy Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. Geographic Atrophy Key Companies

14. Geographic Atrophy Key Products

15. Geographic Atrophy Unmet Needs

16 . Geographic Atrophy Market Drivers and Barriers

17. Geographic Atrophy Future Perspectives and Conclusion

18. Geographic Atrophy Analyst Views

19. Appendix

20. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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