DelveInsight Business Research LLP

“Geographic Atrophy Pipeline Insight, 2023” report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Geographic Atrophy Market.

The Geographic Atrophy Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the Geographic Atrophy Pipeline Report:

• Companies across the globe are diligently working toward developing novel Geographic Atrophy treatment therapies with a considerable amount of success over the years. 
• Geographic Atrophy companies working in the treatment market are Aevitas Therapeutics, Nanoscope Therapeutics, ONL Therapeutics, Roche, NGM Biopharmaceuticals, Annexon, Genentech, Apellis Pharmaceuticals, Pegol Iveric Bio, and others, are developing therapies for the Geographic Atrophy treatment 

• Emerging Geographic Atrophy therapies such as – AAV.sFH, MCO 020, ONL 1204, RO7303359, NGM621, ANX 007, OpRegen, Pegcetacoplan, Avacincaptad, and others are expected to have a significant impact on the Geographic Atrophy market in the coming years.   
• In March 2021, For subjects with Geographic Atrophy (GA) secondary to age-related macular degeneration (AMD) who took part in Study APL2-103 (NCT03777332) or finished the course of treatment at Month 24 of either Study APL2-303 (Derby, NCT03525613) or Study APL2-304 (Oaks, NCT03525600), Apellis Pharmaceuticals started a Phase III, open-label, multicenter extension study
• In July 2022, The US Food and Drug Administration (FDA) accepted and granted Priority Review designation for the intravitreal pegcetacoplan New Drug Application (NDA), according to a statement from Apellis Pharmaceuticals, Inc. A targeted C3therapy under development called pegcetacoplan is used to treat Geographic Atrophy (GA), which is a complication of age-related macular degeneration (AMD)
• In November 2022, providing an update on its New Drug Application (NDA) for intravitreal pegcetacoplan to treat Geographic Atrophy (GA) secondary to age-related macular degeneration (AMD), Apellis Pharmaceuticals, Inc. In support of its application, the business intends to provide the 24-month efficacy data from the Phase 3 DERBY and OAKS investigations

Geographic Atrophy Overview

Geographic Atrophy (GA), also known as atrophic age-related macular degeneration (AMD) or advanced Dry AMD, is an advanced form of age-related macular degeneration that may cause the gradual and irreversible loss of retinal tissue (photoreceptors, retinal pigment epithelium, and choriocappillaris), which may eventually result in a loss of visual function.

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Emerging Geographic Atrophy Drugs Under Different Phases of Clinical Development Include:

• CTx001 Complement Therapeutics
• AAV.sFH: Aevitas Therapeutics
• MCO 020: Nanoscope Therapeutics
• ONL 1204: ONL Therapeutics
• RO7303359: Roche
• NGM621: NGM Biopharmaceuticals
• ANX 007: Annexon
• OpRegen: Genentech
• IONIS-FB-LRx: Ionis Pharmaceuticals
• Zimura: IVERIC bio
• Pegcetacoplan: Apellis Pharmaceuticals
• Avacincaptad: Pegol Iveric Bio

Route of Administration

Geographic Atrophy pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

• Oral
• Parenteral
• Intravenous
• Subcutaneous
• Topical

Molecule Type

Products have been categorized under various Molecule types, such as

• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy 

Geographic Atrophy Pipeline Therapeutics Assessment

• Geographic Atrophy Assessment by Product Type
• Geographic Atrophy By Stage and Product Type
• Geographic Atrophy Assessment by Route of Administration
• Geographic Atrophy By Stage and Route of Administration
• Geographic Atrophy Assessment by Molecule Type
• Geographic Atrophy by Stage and Molecule Type

DelveInsight’s Geographic Atrophy Report covers around 25+ products under different phases of clinical development like

• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Geographic Atrophy product details are provided in the report. Download the Geographic Atrophy pipeline report to learn more about the emerging Geographic Atrophy therapies

Some of the key companies in the Geographic Atrophy Therapeutics Market include:

Key companies developing therapies for Geographic Atrophy are – Ionis Pharmaceuticals, IVERIC bio, Apellis Pharmaceuticals, Inc., NGM Biopharmaceuticals, Annexon Inc., Genentech, Alexion AstraZeneca Rare Disease, ONL Therapeutics, Alkeus Pharmaceuticals, Regenerative Patch Technologies, LLC, Astellas Pharma Inc, Gemini Therapeutics, Boehringer Ingelheim, Cell Cure Neurosciences LTD, Stealth BioTherapeutics Inc., Hemera Biosciences LLC, Gyroscope Therapeutics Limited, Eyevensys, Nanoscope Therapeutics, Inc., Catalyst Biosciences, Novartis, and others.

Geographic Atrophy Pipeline Analysis:

The Geographic Atrophy pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the treatment of Geographic Atrophy with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Geographic Atrophy Treatment.
• Geographic Atrophy key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Geographic Atrophy Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Geographic Atrophy market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about Geographic Atrophy drugs and therapies

Geographic Atrophy Pipeline Market Drivers

• Increase in Patient Burden, development of Novel Treatments, increased Focus on Disease Management and early Diagnosis are some of the important factors that are fueling the Geographic Atrophy Market.

Geographic Atrophy Pipeline Market Barriers

• However, high cost of treatment, side-effects associated and other factors are creating obstacles in the Geographic Atrophy Market growth.

Scope of Geographic Atrophy Pipeline Drug Insight    

• Coverage: Global
• Key Geographic Atrophy Companies: Aevitas Therapeutics, Nanoscope Therapeutics, ONL Therapeutics, Roche, NGM Biopharmaceuticals, Annexon, Genentech, Apellis Pharmaceuticals, Pegol Iveric Bio, and others
• Key Geographic Atrophy Therapies: AAV.sFH, MCO 020, ONL 1204, RO7303359, NGM621, ANX 007, OpRegen, Pegcetacoplan, Avacincaptad, and others
• Geographic Atrophy Therapeutic Assessment: Geographic Atrophy current marketed and Geographic Atrophy emerging therapies
• Geographic Atrophy Market Dynamics: Geographic Atrophy market drivers and Geographic Atrophy market barriers 

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Table of Contents

*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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