DelveInsight’s, “Glioma Pipeline Insight 2023” report provides comprehensive insights about 200+ Glioma companies and 220+ pipeline drugs in the Glioma pipeline landscape. It covers the Glioma pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Glioma therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Key Takeaways from the Glioma Pipeline Report
- DelveInsight’s Glioma pipeline report depicts a robust space with 200+ active players working to develop 220+ pipeline therapies for Glioma treatment.
- The leading Glioma companies working in the market include Denovo Biopharma, AstraZeneca, Pfizer, Chimerix, Bristol-Myers Squibb, Orbus Therapeutics, Northwest Biotherapeutics, Day One Biopharmaceuticals, AiVita Biomedical, Ascletis Pharma Inc., Bristol Myers Squibb, Kazia Therapeutics, HebaBiz Biotech, Biohaven Pharmaceuticals, Vigeo Therapeutics, Hoffman-La-Roche, TVAX Biomedical, Laminar Pharmaceuticals, Kintara Therapeutics, Medicenna Therapeutics, Symphogen A/S, MimiVax, Incyte Corporation, Istari Oncology, Immunomic Therapeutics, Celgene, Sanofi, Merck Sharp & Dohme LLC, Oblato Inc., GlaxoSmithKline, NuvOx Pharma, Epitopoietic Research Corporation, AnHeart Therapeutics, DNAtrix, Arog Pharmaceuticals, CANbridge Pharmaceuticals, Jiangsu Hengrui Medicine, BPGbio Inc., BioMimetix, CNS Pharmaceuticals, and others.
- Promising Glioma Pipeline Therapies in the various stages of development include DS-1001b, Nimotuzumab, Radiotherapy, AP23573, BLZ-100, LY2157299, Temozolomide, Safusidenib, ONC201, PLB1001, YYB-103, and others.
- December 2023: Day One Biopharmaceuticals Inc. announced a study of Phase 3 clinical trials for DAY101 and Chemotherapeutic Agent. This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of DAY101 monotherapy versus standard of care (SoC) chemotherapy in patients with pediatric low-grade glioma (LGG) harboring an activating rapidly accelerated fibrosarcoma (RAF) alteration requiring front-line systemic therapy.
- December 2023: Daiichi Sankyo Co. Ltd announced a study of Phase 2 clinical trials for DS-1001b. This Phase 2 study is conducted to assess the efficacy and safety of DS-1001b in patients with chemotherapy- and radiotherapy-naive IDH1 mutated WHO grade II glioma.
- December 2023: Chimerixannounced a study of Phase 3 clinical trials for ONC201. This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess whether treatment with ONC201 following frontline radiotherapy will extend overall survival and progression-free survival in this population. Eligible participants will have histologically diagnosed H3 K27M-mutant diffuse glioma and have completed standard frontline radiotherapy.
- December 2023: Aveta Biomics Inc. announced a study of Phase 1 & 2 clinical trials for APG-157. The goal of this interventional study is to evaluate the efficacy of APG-157 in combination with Bevacizumab in subjects with recurrent high-grade glioma who have previously progressed on bevacizumab alone.
- December 2023: Boehringer Ingelheimannounced a study of Phase 1 clinical trials for BI 764532. The purpose of this study is to find out the highest dose of BI 764532 that people with a brain tumour that is positive for DLL3 can tolerate. BI 764532 is an antibody-like molecule that can attach and link together the cancer cells and T-cells of the immune system (DLL3/CD3 bispecific). This may help the immune system fight cancer.
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In the Glioma Pipeline Report, detailed description of the drug is given which includes mechanism of action of the drug, Glioma clinical trials studies, NDA approvals (if any), and product development activities comprising the technology, Glioma collaborations, licensing, mergers and acquisition, funding, designations and other product related details. The assessment part of the report embraces, in depth Glioma commercial assessment and clinical assessment of the Glioma pipeline products under development.
Glioma Overview
A glioma is a tumor that forms in the brain or spinal cord. Neuroglial cells also known as glial cells or glia are quite different from nerve cells. They do not participate directly in synaptic interactions and electrical signaling, although their supportive functions help define synaptic contacts and maintain the signaling abilities of neurons. Glia are more numerous than nerve cells in the brain, outnumbering them by a ratio of perhaps 3 to 1. Although glial cells also have complex processes extending from their cell bodies, they are generally smaller than neurons, and they lack axons and dendrites.
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Glioma Emerging Drugs Profile
- Tofacitinib: Pfizer
- Enzastaurin: Denovo BioPharma
- MDNA55: Medicenna Therapeutics, Inc.
- Sym004: Symphogen A/S
- MN-166: MediciNova
Glioma Therapeutics Assessment
There are approx. 200+ Glioma companies which are developing the therapies for Glioma Disease. The Glioma companies which have their Glioma Disease drug candidates in the most advanced stage, i.e. Phase III include, Denovo BioPharma. The Glioma pipeline report proffers an integral view of the emerging Glioma segmented by stage, product type, molecule type, and route of administration.
Glioma Disease pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Intravenous
- Subcutaneous
- Oral
- Intramuscular
Dive deep into rich insights for new Glioma, visit @ Glioma Treatment Landscape
Glioma Products have been categorized under various Molecule types such as
- Monoclonal antibody
- Small molecule
- Peptide
Scope of the Glioma Pipeline Report
- Coverage- Global
- Glioma Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
- Glioma Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
- Glioma Companies- Denovo Biopharma, AstraZeneca, Pfizer, Chimerix, Bristol-Myers Squibb, Orbus Therapeutics, Northwest Biotherapeutics, Day One Biopharmaceuticals, AiVita Biomedical, Ascletis Pharma Inc., Bristol Myers Squibb, Kazia Therapeutics, HebaBiz Biotech, Biohaven Pharmaceuticals, Vigeo Therapeutics, Hoffman-La-Roche, TVAX Biomedical, Laminar Pharmaceuticals, Kintara Therapeutics, Medicenna Therapeutics, Symphogen A/S, MimiVax, Incyte Corporation, Istari Oncology, Immunomic Therapeutics, Celgene, Sanofi, Merck Sharp & Dohme LLC, Oblato Inc., GlaxoSmithKline, NuvOx Pharma, Epitopoietic Research Corporation, AnHeart Therapeutics, DNAtrix, Arog Pharmaceuticals, CANbridge Pharmaceuticals, Jiangsu Hengrui Medicine, BPGbio Inc., BioMimetix, CNS Pharmaceuticals, and others.
- Glioma Therapies- DS-1001b, Nimotuzumab, Radiotherapy, AP23573, BLZ-100, LY2157299, Temozolomide, Safusidenib, ONC201, PLB1001, YYB-103, and others.
For further information on the Glioma Pipeline Therapeutics, reach out @ Glioma Therapeutics Segmentation
Table of Content
- Introduction
- Executive Summary
- Glioma Disease: Overview
- Glioma Pipeline Therapeutics
- Glioma Therapeutic Assessment
- Glioma Disease– DelveInsight’s Analytical Perspective
- Late Stage Products (Phase III)
- Enzastaurin: Denovo BioPharma
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- MDNA55: Medicenna Therapeutics, Inc.
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I/II)
- Zotiraciclib: Adastra Pharmaceuticals
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- RGN6024: Reglagene, Inc.
- Drug profiles in the detailed report…..
- Inactive Products
- Glioma Disease Key Companies
- Glioma Disease Key Products
- Glioma Disease- Unmet Needs
- Glioma Disease- Market Drivers and Barriers
- Glioma Disease- Future Perspectives and Conclusion
- Glioma Disease Analyst Views
- Glioma Disease Key Companies
- Appendix
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