Hypoparathyroidism is a rare endocrine disorder characterized by low-calcium and high-phosphate levels, in the setting of a simultaneously low or inappropriate level of normal Parathyroid hormone (PTH). The most frequent etiology is surgical removal or loss of viability of parathyroid glands. The second most common etiology is autoimmune hypoparathyroidism, related to autoimmune polyglandular syndrome type 1 or isolated hypoparathyroidism due to activating antibodies to the CaSR.
Severe hypomagnesemia is an uncommon but reversible cause of hypoparathyroidism. Other rarer causes of hypoparathyroidism include infiltrative disorders, such as hemochromatosis, metastases or granulomatous diseases, radiation-induced destruction of parathyroid glands, hungry bone syndrome post parathyroidectomy and HIV infection, and others.
The DelveInsight Hypoparathyroidism epidemiology report gives a thorough understanding of the Hypoparathyroidism by including details such as disease definition, symptoms, causes, pathophysiology, and diagnosis.
It also provides treatment algorithms and treatment guidelines for Hypoparathyroidism in the US, Europe, and Japan. The report covers the detailed information of the Hypoparathyroidism epidemiology scenario in seven major countries (US, EU5, and Japan).
Key Highlights Of The Report
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Hypoparathyroidism is a rare disease, even though country-specific data is limited, and the epidemiological understanding has been increased recently with quantification of data. According to the review of literature, the prevalence of hypoparathyroidism in the United States reported as 37 per 100,000 person-years. Among this, 72% of cases belong to females (Clarke et al.). Only a few studies exist on the epidemiology of hypoparathyroidism in Europe (in Denmark, Netherlands, and Hungary).
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Surgical removal is the most common cause of Hypoparathyroidism. Anterior neck surgery is the most common cause of acquired hypoparathyroidism, and responsible for about 75% of cases with a prevalence of 29 per 100 000 person-years; the remaining cases are related to non-surgical or more rarely, related to a genetic disorder. (Bilezikian et al.)
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Despite precautions and expertise in surgical management, about 20 –30% of patients develop transient and 1–7% develop permanent postsurgical hypoparathyroidism after total thyroidectomy. (Shoback et al.)
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Hypoparathyroidism Epidemiology
Delveinsight’s Hypoparathyroidism epidemiology division provides insights about historical and current patient pool and forecasted trends for every seven major countries.
The Hypoparathyroidism epidemiology data are studied through all possible divisions to give a better understanding of the Disease scenario in 7MM.
The Hypoparathyroidism epidemiology segment covers the epidemiology data in the US, EU5 countries (Germany, Spain, Italy, France, and the UK), and Japan from 2017 to 2030.
It also helps to recognize the causes of current and forecasted trends by exploring numerous studies, survey reports and views of key opinion leaders.
Scope of the Report
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The report provides insight into the historical and forecasted patient pool of Hypoparathyroidism in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan.
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The report assesses the disease risk and burden and highlights the unmet needs of Hypoparathyroidism.
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The report helps to recognize the growth opportunities in the 7MM with respect to the patient population.
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The Hypoparathyroidism report provides a detailed overview explaining Hypoparathyroidism causes, symptoms, classification, pathophysiology, diagnosis and treatment patterns.
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The Hypoparathyroidism Epidemiology Report and Model provide an overview of the risk factors and global trends of Hypoparathyroidism in the seven major markets (7MM:US, France, Germany, Italy, Spain, UK, and Japan).
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The report provides the segmentation of the Hypoparathyroidism epidemiology.
Key Questions Covered In The Hypoparathyroidism Report Include:
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What will be the growth opportunities in the 7MM with respect to the patient population pertaining to Hypoparathyroidism?
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What are the key findings pertaining to the Hypoparathyroidism epidemiology across 7MM and which country will have the highest number of patients during the forecast period (2017-2030)?
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What would be the total number of patients of Hypoparathyroidism across the 7MM during the forecast period (2017-2030)?
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Among the EU5 countries, which country will have the highest number of patients during the forecast period (2017-2030)?
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At what CAGR the patient population is expected to grow in 7MM during the forecast period (2017-2030)?
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What is the disease risk, burden and unmet needs of the Hypoparathyroidism?
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What are the currently available treatments of Hypoparathyroidism?
Key Benefit of Hypoparathyroidism Epidemiology Report
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The Hypoparathyroidism Epidemiology report will allow the user to –
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Develop business strategies by understanding the trends shaping and driving the global Hypoparathyroidism market
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Quantify patient populations in the global Hypoparathyroidism market to improve product design, pricing, and launch plans
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Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for Hypoparathyroidism therapeutics in each of the markets covered
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Understand the magnitude of Hypoparathyroidism population by its epidemiology
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The Hypoparathyroidism Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over 11-year forecast period using reputable sources
Table of Contents
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Key Insights
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Executive Summary of Hypoparathyroidism
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Hypoparathyroidism Disease Background and Overview
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Hypoparathyroidism Sign and Symptoms
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Hypoparathyroidism Pathophysiology
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Hypoparathyroidism Risk Factors
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Hypoparathyroidism Diagnosis
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Hypoparathyroidism Patient Journey
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Hypoparathyroidism Epidemiology and Patient Population
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Hypoparathyroidism Treatment Algorithm, Current Treatment, and Medical Practices
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KOL Views on Hypoparathyroidism
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Hypoparathyroidism Unmet Needs
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Appendix
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DelveInsight Capabilities
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Disclaimer
*The table of contents is not exhaustive; will be provided in the final report
About DelveInsight
DelveInsight is a leading Business Consultant, and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing end to end comprehensive solutions to improve their performance.
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