“Hypoparathyroidism Pipeline Insight, 2024“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Hypoparathyroidism Market.

The Hypoparathyroidism Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the Hypoparathyroidism Pipeline Report:

• Companies across the globe are diligently working toward developing novel Hypoparathyroidism treatment therapies with a considerable amount of success over the years. 

• Hypoparathyroidism companies working in the treatment market are Ascendis Pharma, Bridgebio/Calcilytix Therapeutics, Amolyt Pharma, MBX Bioscience, Amorphical Ltd., Entera Bio Ltd., Visen Pharmaceuticals, and others, are developing therapies for the Hypoparathyroidism treatment 

• Emerging Hypoparathyroidism therapies in the different phases of clinical trials are- TRANSCON PTH (palopegteriparatide), Encaleret (BBP-305/CLTX-305), AZP-3601 (eneboparatide), MBX 2109, AMOR-1, EBP05, TransCon PTH, and others are expected to have a significant impact on the Hypoparathyroidism market in the coming years.   

• In August 2024, US biotechnology firm MBX Biosciences has administered the first dose to a participant in a Phase II trial for MBX 2109, a potential therapy for chronic hypoparathyroidism (HP). The Avail trial is designed as a randomized, double-blind, placebo-controlled study, enrolling 48 adult patients with Hypoparathyroidism.

• In August 2024, Ascendis Pharma has received approval from the US Food and Drug Administration (FDA) for its drug YORVIPATH (palopegteriparatide) to treat hypoparathyroidism in adults. Hypoparathyroidism is a rare endocrine disorder marked by inadequate levels of parathyroid hormone, which impacts various organs. YORVIPATH, a prodrug of parathyroid hormone (PTH[1-34]), is given once daily.

Hypoparathyroidism Overview

Hypoparathyroidism is a rare endocrine disorder characterized by insufficient production of parathyroid hormone (PTH) from the parathyroid glands. PTH is crucial for regulating calcium and phosphorus levels in the body. The deficiency of PTH leads to low calcium levels (hypocalcemia) and high phosphorus levels (hyperphosphatemia), resulting in symptoms such as muscle cramps, tingling in the extremities, fatigue, and in severe cases, seizures or cardiac issues. The condition can be caused by surgical removal of the parathyroid glands, autoimmune disorders, genetic factors, or idiopathic reasons. Treatment typically involves calcium and vitamin D supplementation to manage symptoms and maintain normal calcium levels.

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Emerging Hypoparathyroidism Drugs Under Different Phases of Clinical Development Include:

• TRANSCON PTH (palopegteriparatide): Ascendis Pharma

• Encaleret (BBP-305/CLTX-305): Bridgebio/Calcilytix Therapeutics

• AZP-3601 (eneboparatide): Amolyt Pharma

• MBX 2109: MBX Bioscience

• AMOR-1: Amorphical Ltd.

• EBP05: Entera Bio Ltd.

• TransCon PTH: Visen Pharmaceuticals

Hypoparathyroidism Route of Administration

Hypoparathyroidism pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

• Oral

• Parenteral

• Intravenous

• Subcutaneous

• Topical

Hypoparathyroidism Molecule Type

Hypoparathyroidism Products have been categorized under various Molecule types, such as

• Monoclonal Antibody

• Peptides

• Polymer

• Small molecule

• Gene therapy 

Hypoparathyroidism Pipeline Therapeutics Assessment

• Hypoparathyroidism Assessment by Product Type

• Hypoparathyroidism By Stage and Product Type

• Hypoparathyroidism Assessment by Route of Administration

• Hypoparathyroidism By Stage and Route of Administration

• Hypoparathyroidism Assessment by Molecule Type

• Hypoparathyroidism by Stage and Molecule Type

DelveInsight’s Hypoparathyroidism Report covers around 10+ products under different phases of clinical development like

• Late-stage products (Phase III)

• Mid-stage products (Phase II)

• Early-stage product (Phase I)

• Pre-clinical and Discovery stage candidates

• Discontinued & Inactive candidates

• Route of Administration

Further Hypoparathyroidism product details are provided in the report. Download the Hypoparathyroidism pipeline report to learn more about the emerging Hypoparathyroidism therapies

Some of the key companies in the Hypoparathyroidism Therapeutics Market include:

Key companies developing therapies for Hypoparathyroidism are – Amgen Inc., Ascendis Pharma A/S, F. Hoffmann-La Roche Ltd, ProLynx, Inc., Extend Biosciences, Inc., Takeda Pharmaceutical Company Limited., Entera Bio Ltd., BionPharma Inc., Teva Pharmaceuticals Ltd., and others.

Hypoparathyroidism Pipeline Analysis:

The Hypoparathyroidism pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the treatment of Hypoparathyroidism with aggregate therapies developed by each company for the same.

• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Hypoparathyroidism Treatment.

• Hypoparathyroidism key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

• Hypoparathyroidism Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 

• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Hypoparathyroidism market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about Hypoparathyroidism drugs and therapies

Hypoparathyroidism Pipeline Market Drivers

• Rising Incidence, Advancements in Research, Increased Awareness, Regulatory Support, Improved Diagnostic Techniques, are some of the important factors that are fueling the Hypoparathyroidism Market.

Hypoparathyroidism Pipeline Market Barriers

• However, High Treatment Costs, Limited Market Size, Complexity of Treatment, Complexity of Treatment, Limited Clinical Data, and other factors are creating obstacles in the Hypoparathyroidism Market growth.

Scope of Hypoparathyroidism Pipeline Drug Insight    

• Coverage: Global

• Key Hypoparathyroidism Companies: Ascendis Pharma, Bridgebio/Calcilytix Therapeutics, Amolyt Pharma, MBX Bioscience, Amorphical Ltd., Entera Bio Ltd., Visen Pharmaceuticals, and others

• Key Hypoparathyroidism Therapies: TRANSCON PTH (palopegteriparatide), Encaleret (BBP-305/CLTX-305), AZP-3601 (eneboparatide), MBX 2109, AMOR-1, EBP05, TransCon PTH, and others

• Hypoparathyroidism Therapeutic Assessment: Hypoparathyroidism current marketed and Hypoparathyroidism emerging therapies

• Hypoparathyroidism Market Dynamics: Hypoparathyroidism market drivers and Hypoparathyroidism market barriers 

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Table of Contents

1. Hypoparathyroidism Report Introduction

2. Hypoparathyroidism Executive Summary

3. Hypoparathyroidism Overview

4. Hypoparathyroidism- Analytical Perspective In-depth Commercial Assessment

5. Hypoparathyroidism Pipeline Therapeutics

6. Hypoparathyroidism Late Stage Products (Phase II/III)

7. Hypoparathyroidism Mid Stage Products (Phase II)

8. Hypoparathyroidism Early Stage Products (Phase I)

9. Hypoparathyroidism Preclinical Stage Products

10. Hypoparathyroidism Therapeutics Assessment

11. Hypoparathyroidism Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. Hypoparathyroidism Key Companies

14. Hypoparathyroidism Key Products

15. Hypoparathyroidism Unmet Needs

16 . Hypoparathyroidism Market Drivers and Barriers

17. Hypoparathyroidism Future Perspectives and Conclusion

18. Hypoparathyroidism Analyst Views

19. Appendix

20. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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