(Albany, USA) DelveInsight’s “Major depressive disorder Market Insights, Epidemiology, and Market Forecast-2034” report delivers an in-depth understanding of Major depressive disorder, historical and forecasted epidemiology as well as the Major depressive disorder market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.
The Major depressive disorder market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Major depressive disorder market size from 2020 to 2034, segmented by seven major markets. The Report also covers current Major depressive disorder treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Major depressive disorder market.
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Some facts of the Major depressive disorder Market Report are:
- According to DelveInsight, Major depressive disorder market size is expected to grow at a decent CAGR by 2034.
- The Major Depressive Disorder Treatment Market Size in the 7MM was approximately USD 7,165 million in 2023.
- Leading Major depressive disorder companies working in the market are Takeda Pharmaceuticals, Forest Laboratories, Otsuka Pharmaceuticals, Janssen Research & Development, Axsome Therapeutics, AbbVie, SAGE Therapeutics, Minerva Neurosciences, Luye Pharma, Relmada Therapeutics, BioLite Inc., VistaGen Therapeutics, Praxis Precision Medicines, Intra-Cellular Therapies, Neurocrine Biosciences, Arrivo Bioventures, Sirstei Pharmaceuticals, Alto Neuroscience, Chase Therapeutics, Neumora Therapeutics, Inc., BlackThorn Therapeutics, Inc., Otsuka Pharmaceutical Co., Ltd., Fabre-Kramer Pharmaceuticals, Novartis and others.
- Key Major depressive disorder Therapies expected to launch in the market are VRAYLAR, Zuranolone, Seltorexant (JNJ42847922), REL-1017, ABV-1504, Itruvone (PH10), LPCN 1154, and many others.
- With the anticipated introduction of new treatments such as COMP360 (COMPASS Pathways), Zuranolone (SAGE Therapeutics/Biogen), LY03005 (Luye Pharma), REL-1017 (Relmada Therapeutics), Seltorexant (Minerva Neurosciences/Janssen Pharmaceutical), ABV-1504 (BioLite/ABVC BioPharma), and other and increasing disease awareness, it’s reasonable to expect a significant transformation in the major depressive disorder market in the coming years.
- In June 2024, Lipocine announced positive topline results from a pivotal pharmacokinetic study, confirming that LPCN 1154 is bioequivalent to IV brexanolone for PPD treatment. Lipocine aims to submit the NDA by the end of the fourth quarter of 2024.
- On November 12, 2024, Magstim, a global leader in neuroscience and mental health treatment, received FDA clearance for its Horizon Inspire System. This advanced transcranial magnetic stimulation (TMS) technology is designed to assist physicians, nurse practitioners, clinicians, and researchers in treating patients with major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and anxious depression.
- On November 5, 2024, the U.S. FDA approved an Investigational New Drug (IND) application from Damona Pharmaceuticals, enabling the company to begin a Phase I trial of DPX-101. The drug is designed to treat cognitive disabilities in major depressive disorder and other brain disorders.
Major depressive disorder Overview
Major Depressive Disorder (MDD), commonly referred to as depression, is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a loss of interest or pleasure in daily activities. It significantly affects mood, cognition, and physical health, often impairing a person’s ability to function socially or occupationally.
The symptoms of Major Depressive Disorder include depressed mood, fatigue, difficulty concentrating, changes in appetite or sleep patterns, feelings of worthlessness or guilt, and, in severe cases, thoughts of self-harm or suicide. These symptoms must persist for at least two weeks to meet the diagnostic criteria. The condition can range from mild to severe, with some individuals experiencing recurrent episodes.
The exact cause of Major Depressive Disorder is not fully understood, but it is believed to result from a combination of genetic, biological, environmental, and psychological factors. Imbalances in brain neurotransmitters like serotonin, dopamine, and norepinephrine play a significant role.
Major Depressive Disorder Treatment typically involves psychotherapy (such as cognitive-behavioral therapy), medication (antidepressants like SSRIs or SNRIs), or a combination of both. For resistant cases, other interventions like electroconvulsive therapy (ECT) or transcranial magnetic stimulation (TMS) may be considered.
Early diagnosis and treatment are crucial to improving outcomes and preventing complications such as chronic disability or co-occurring conditions like anxiety disorders.
For severe cases of major depression, electroconvulsive therapy is the most effective option. The current range of recommended pharmacological treatments for major depressive disorder primarily includes antidepressants such as monoamines, tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs), and selective reuptake inhibitors, including medications like VRAYLAR, BRINTELLIX (now TRINTELLIX), SPRAVATO, REXULTI, and FETZIMA.
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Major depressive disorder Market
The Major depressive disorder market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Major depressive disorder market trends by analyzing the impact of current Major depressive disorder therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.
This segment gives a thorough detail of the Major depressive disorder market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Major depressive disorder market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the Major depressive disorder market in 7MM is expected to witness a major change in the study period 2020-2034.
Major depressive disorder Epidemiology
The Major depressive disorder epidemiology section provides insights into the historical and current Major depressive disorder patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Major depressive disorder market report also provides the diagnosed patient pool, trends, and assumptions.
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Major depressive disorder Drugs Uptake
This section focuses on the uptake rate of the potential Major depressive disorder drugs recently launched in the Major depressive disorder market or expected to be launched in 2020-2034. The analysis covers the Major depressive disorder market uptake by drugs, patient uptake by therapies, and sales of each drug.
Major depressive disorder Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Major depressive disorder market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Major depressive disorder Pipeline Development Activities
The Major depressive disorder report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Major depressive disorder key players involved in developing targeted therapeutics.
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Major depressive disorder Therapeutics Assessment
Major key companies are working proactively in the Major depressive disorder Therapeutics market to develop novel therapies which will drive the Major depressive disorder treatment markets in the upcoming years are Takeda Pharmaceuticals, Forest Laboratories, Otsuka Pharmaceuticals, Janssen Research & Development, Axsome Therapeutics, AbbVie, SAGE Therapeutics, Minerva Neurosciences, Luye Pharma, Relmada Therapeutics, BioLite Inc., VistaGen Therapeutics, Praxis Precision Medicines, Intra-Cellular Therapies, Neurocrine Biosciences, Arrivo Bioventures, Sirstei Pharmaceuticals, Alto Neuroscience, Chase Therapeutics, Neumora Therapeutics, Inc., BlackThorn Therapeutics, Inc., Otsuka Pharmaceutical Co., Ltd., Fabre-Kramer Pharmaceuticals, Novartis and others.
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Major depressive disorder Report Key Insights
1. Major depressive disorder Patient Population
2. Major depressive disorder Market Size and Trends
3. Key Cross Competition in the Major depressive disorder Market
4. Major depressive disorder Market Dynamics (Key Drivers and Barriers)
5. Major depressive disorder Market Opportunities
6. Major depressive disorder Therapeutic Approaches
7. Major depressive disorder Pipeline Analysis
8. Major depressive disorder Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Major depressive disorder Market
Table of Contents
1. Key Insights
2. Executive Summary
3. Major depressive disorder Competitive Intelligence Analysis
4. Major depressive disorder Market Overview at a Glance
5. Major depressive disorder Disease Background and Overview
6. Major depressive disorder Patient Journey
7. Major depressive disorder Epidemiology and Patient Population
8. Major depressive disorder Treatment Algorithm, Current Treatment, and Medical Practices
9. Major depressive disorder Unmet Needs
10. Key Endpoints of Major depressive disorder Treatment
11. Major depressive disorder Marketed Products
12. Major depressive disorder Emerging Therapies
13. Major depressive disorder Seven Major Market Analysis
14. Attribute Analysis
15. Major depressive disorder Market Outlook (7 major markets)
16. Major depressive disorder Access and Reimbursement Overview
17. KOL Views on the Major depressive disorder Market
18. Major depressive disorder Market Drivers
19. Major depressive disorder Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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