(Albany, US) Metachromatic Leukodystrophy (MLD) is a rare inherited disorder characterized by the accumulation of fats called sulfatides in cells. This accumulation especially affects cells in the nervous system that produce myelin, the substance that insulates and protects nerves. Nerve cells covered by myelin make up a tissue called white matter. This condition is called metachromatic leukodystrophy because when viewed under a microscope, sulfatide accumulation in cells appears as granules that are colored differently than other cellular material (metachromatic).
DelveInsight’s “Metachromatic Leukodystrophy Market Insights, Epidemiology, and Market Forecast-2032” report delivers an in-depth understanding of the Metachromatic Leukodystrophy (MLD), historical and forecasted epidemiology as well as the Metachromatic Leukodystrophy (MLD) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Some facts of Metachromatic Leukodystrophy Market are:
- According to the United Leukodystrophy Foundation, MLD is inherited in an autosomal recessive manner, and is most commonly caused by a mutation in a gene called Arylsulfatase A (ASA), also called sulfatide sulfatase. The protein produced by ASA is present in the lysosomal compartment of the cell.
- The prognosis for MLD is poor. Most children within the infantile form die by age 5. Symptoms of the juvenile form progress with death occurring 10 to 20 years following onset. Those persons affected by the adult form typically die within 6 to 14 years following onset of symptoms.
- As per the MalaCards Human Disease Database, MLD is inherited in an autosomal recessive manner with a prevalence of 1-9 per 100000 in Europe, United States and worldwide and the age of onset of different forms of MLD varies.
- As per the Myriad Women’s Health, MLD is divided into three forms infantile (early-onset), juvenile (late-onset), and adult (late-onset) out of which infantile form is the most common with 50 to 60% of all the cases.
- Through various secondary studies it can be concluded that MLD affects both males and females equally
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Scope of the Metachromatic Leukodystrophy Market Report:
- The report covers the descriptive overview of Metachromatic Leukodystrophy (MLD), explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
- Comprehensive insight has been provided into the Metachromatic Leukodystrophy (MLD) epidemiology and treatment in the 7MM
- Additionally, an all-inclusive account of both the current and emerging therapies for Metachromatic Leukodystrophy (MLD) is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
- A detailed review of the Metachromatic Leukodystrophy (MLD) market; historical and forecasted is included in the report, covering drug outreach in the 7MM
- The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Metachromatic Leukodystrophy (MLD) market
Some of Metachromatic Leukodystrophy Companies are:
- Takeda
- Talaris Therapeutics
- Magenta Therapeutics
- And Many Others
Metachromatic Leukodystrophy Drugs are:
- TAK-611
- FCR001
- SHP611
- MGTA-456
- And Many Others
To know more about Metachromatic Leukodystrophy Pipeline therapies and companies, Click Here: https://www.delveinsight.com/sample-request/metachromatic-leukodystrophy-mld-market
Table of Contents:
1. Key Insights
2. Executive Summary of Metachromatic Leukodystrophy (MLD)
3. Competitive Intelligence Analysis for Metachromatic Leukodystrophy (MLD)
4. Metachromatic Leukodystrophy (MLD): Market Overview at a Glance
5. Metachromatic Leukodystrophy (MLD): Disease Background and Overview
6. Patient Journey
7. Metachromatic Leukodystrophy (MLD) Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Metachromatic Leukodystrophy (MLD) Unmet Needs
10. Key Endpoints of Metachromatic Leukodystrophy (MLD) Treatment
11. Metachromatic Leukodystrophy (MLD) Marketed Products
12. Metachromatic Leukodystrophy (MLD) Emerging Therapies
13. Metachromatic Leukodystrophy (MLD): Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Metachromatic Leukodystrophy (MLD)
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
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