Phenylacetic Acid Hydrazide is a chemical compound that can be used as an intermediate for the synthesis of various pharmaceuticals, such as anticonvulsants, antidepressants, antihistamines, and anti-inflammatory agents. The compound is also known by several synonyms, such as Phenylaceticacidhydrazide, 2-phenylethanehydrazide, Phenylacetichydrazide, (2-Phenylacetyl)hydrazine, Aceticacid,phenyl-,hydrazide, Phenaceticacidhydrazide, Phenylacetylhydrazide, and 2-PHENYLACETICACIDHYDRAZIDE. Phenylacetic Acid Hydrazide has a CAS number of 937-39-3, and a molecular formula of C8H10N2O. Phenylacetic Acid Hydrazide has a molecular weight of 150.18, and an appearance of white crystal.
In this article, we will describe the detailed product properties and performance of Phenylacetic Acid Hydrazide, and how it can be used, stored, and handled safely and effectively.
Physical and Chemical PropertiesPhenylacetic Acid Hydrazide has the following physical and chemical properties:
• Appearance and odor: Phenylacetic Acid Hydrazide is a white crystal with no data on odor.• Melting and boiling point: Phenylacetic Acid Hydrazide has a melting point of 115-116 °C (lit.) and a boiling point of 364.9°C at 760 mmHg.• pH value: Phenylacetic Acid Hydrazide has no data on pH value.• Flash point and spontaneous combustion temperature: Phenylacetic Acid Hydrazide has a flash point of 42°C (lit.) and no data on spontaneous combustion temperature.• Decomposition temperature and explosion limit: Phenylacetic Acid Hydrazide has no data on decomposition temperature and explosion limit.• Evaporation rate and saturated vapor pressure: Phenylacetic Acid Hydrazide has no data on evaporation rate and saturated vapor pressure.• Flammability and vapor density: Phenylacetic Acid Hydrazide has no data on flammability and vapor density.• Relative density and N-octanol/water partition coefficient: Phenylacetic Acid Hydrazide has a relative density of 1.138g /cm3 and no data on N-octanol/water partition coefficient.• Odor threshold and solubility: Phenylacetic Acid Hydrazide has no data on odor threshold and solubility.• Viscosity and stability: Phenylacetic Acid Hydrazide has no data on viscosity and is stable when stored and used at normal ambient temperature.
Phenylacetic Acid Hydrazide has some physical and chemical properties that are not available or not measured, which may limit its application and evaluation.
Product Performance and ApplicationPhenylacetic Acid Hydrazide has the following product performance and application:
• Product performance: Phenylacetic Acid Hydrazide is a hydrazide compound that can react with various carbonyl compounds, such as aldehydes, ketones, esters, and acids, to form hydrazones, which are useful intermediates for the synthesis of heterocyclic compounds, such as oxadiazoles, triazoles, and pyrazoles. Phenylacetic Acid Hydrazide can also undergo oxidation, reduction, and substitution reactions, to form various derivatives with different biological activities, such as anticonvulsants, antidepressants, antihistamines, and anti-inflammatory agents. Phenylacetic Acid Hydrazide has a high purity and a high yield, and can be easily synthesized, purified, and characterized by various analytical techniques.
• Product application: Phenylacetic Acid Hydrazide can be used as an intermediate for the synthesis of various pharmaceuticals, such as phenytoin, phenelzine, diphenhydramine, and ibuprofen. Phenylacetic Acid Hydrazide can also be used as a building block for the synthesis of various organic compounds, such as phenylacetylhydrazine, phenylacetylhydrazone, and phenylacetylhydrazide oxide. Phenylacetic Acid Hydrazide can also be used as a reagent for the detection of aldehydes and ketones.
Phenylacetic Acid Hydrazide has a good product performance and a wide product application, which makes it a valuable and versatile product in the chemical industry.
Product Safety and HandlingPhenylacetic Acid Hydrazide has the following product safety and handling:
• Product safety: Phenylacetic Acid Hydrazide is classified as an acute oral toxicant, which may cause harm if swallowed. Phenylacetic Acid Hydrazide may also cause skin and eye irritation, and respiratory irritation if inhaled. Phenylacetic Acid Hydrazide may also pose a fire hazard if exposed to heat, sparks, or flames. Phenylacetic Acid Hydrazide should be handled with caution and care, and the following precautionary measures should be followed:
• Avoid contact with skin, eyes, and clothing.• Wear appropriate personal protective equipment, such as gloves, goggles, and masks.• Wash hands thoroughly after handling.• Do not eat, drink, or smoke when using this product.• Store in a cool, dry, and well-ventilated place, away from heat, sparks, and flames.• Dispose of the product and its container in accordance with local, regional, national, and international regulations.
• Product handling: Phenylacetic Acid Hydrazide should be handled with care and caution, and the following handling procedures should be followed:
• First aid measures: In case of exposure to Phenylacetic Acid Hydrazide, the following first aid measures should be taken:• Inhalation: If inhaled, move the patient to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention.• Skin contact: Remove contaminated clothing and rinse skin thoroughly with soap and water. If you feel uncomfortable, seek medical attention.• Eye contact: Separate eyelids and rinse with running water or normal saline. Seek immediate medical attention.• Ingestion: Gargle, do not induce vomiting. Seek immediate medical attention.
• Fire protection measures: In case of fire involving Phenylacetic Acid Hydrazide, the following fire protection measures should be taken:• Extinguishing agent: Extinguish fire with water mist, dry powder, foam or carbon dioxide extinguishing agent. Avoid using direct running water to extinguish the fire, which may cause splashing of flammable liquid and spread the fire.• Special hazards: No data• Fire precautions and protective measures: Fire personnel should wear air breathing apparatus, wear full fire clothing, and fight fire upwind. If possible, move the container from the fire to an open area. Containers in the fire area must be evacuated immediately if they are discolored or emit sound from the safety relief device. Isolate the accident site and prohibit irrelevant personnel from entering. Contain and treat fire water to prevent environmental pollution.
Phenylacetic Acid Hydrazide has some product safety and handling issues, which require careful and responsible use and disposal.
ConclusionPhenylacetic Acid Hydrazide is a chemical compound that can be used as an intermediate for the synthesis of various pharmaceuticals, such as anticonvulsants, antidepressants, antihistamines, and anti-inflammatory agents. Phenylacetic Acid Hydrazide has a high purity and a high yield, and can be easily synthesized, purified, and characterized by various analytical techniques. Phenylacetic Acid Hydrazide has some physical and chemical properties that are not available or not measured, which may limit its application and evaluation. Phenylacetic Acid Hydrazide has a good product performance and a wide product application, which makes it a valuable and versatile product in the chemical industry. Phenylacetic Acid Hydrazide has some product safety and handling issues, which require careful and responsible use and disposal.
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