The Polycystic Kidney Disease Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

“Polycystic Kidney Disease Pipeline Insight, 2024“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Polycystic Kidney Disease Market.

Some of the key takeaways from the Polycystic Kidney Disease Pipeline Report:

• Companies across the globe are diligently working toward developing novel Polycystic Kidney Disease treatment therapies with a considerable amount of success over the years. 

• Polycystic Kidney Disease companies working in the treatment market are Hannover Medical School, Otsuka Pharmaceutical, Rege Nephro Co., Ltd., Otsuka Pharmaceutical, and others, are developing therapies for the Polycystic Kidney Disease treatment 

• Emerging Polycystic Kidney Disease therapies in the different phases of clinical trials are- Empagliflozin, Tolvaptan (OPC-41061), Tamibarotene, Tolvaptan Suspension, and others are expected to have a significant impact on the Polycystic Kidney Disease market in the coming years.   

• In January 2024, Regulus Therapeutics has completed patient enrolment for the third cohort in its Phase Ib multiple-ascending dose (MAD) study of RGLS8429, a potential treatment for ADPKD. RGLS8429 aims to inhibit miR-17 and specifically target the kidneys. The Phase Ib MAD study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of RGLS8429 in adults with ADPKD.

• In November 2023, PYC Therapeutics has announced the results of a study using human 3-dimensional models derived from patients with end-stage renal failure due to Autosomal Dominant Polycystic Kidney Disease (PKD). The study demonstrated that PYC-003, an investigational drug candidate developed by PYC to target the root cause of the disease, is effective. These 3D patient-derived cyst models are considered the ‘gold standard’ pre-clinical assay for evaluating drug candidates for this condition.

Polycystic Kidney Disease Overview

Polycystic Kidney Disease (PKD) is a genetic disorder characterized by the growth of numerous fluid-filled cysts in the kidneys. These cysts can enlarge the kidneys and interfere with their ability to function properly.

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Emerging Polycystic Kidney Disease Drugs Under Different Phases of Clinical Development Include:

• Empagliflozin: Hannover Medical School

• Tolvaptan (OPC-41061): Otsuka Pharmaceutical

• Tamibarotene: Rege Nephro Co., Ltd.

• Tolvaptan Suspension: Otsuka Pharmaceutical

Polycystic Kidney Disease Route of Administration

Polycystic Kidney Disease pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

• Oral

• Parenteral

• Intravenous

• Subcutaneous

• Topical

Polycystic Kidney Disease Molecule Type

Polycystic Kidney Disease Products have been categorized under various Molecule types, such as

• Monoclonal Antibody

• Peptides

• Polymer

• Small molecule

• Gene therapy 

Polycystic Kidney Disease Pipeline Therapeutics Assessment

• Polycystic Kidney Disease Assessment by Product Type

• Polycystic Kidney Disease By Stage and Product Type

• Polycystic Kidney Disease Assessment by Route of Administration

• Polycystic Kidney Disease By Stage and Route of Administration

• Polycystic Kidney Disease Assessment by Molecule Type

• Polycystic Kidney Disease by Stage and Molecule Type

DelveInsight’s Polycystic Kidney Disease Report covers around 10+ products under different phases of clinical development like

• Late-stage products (Phase III)

• Mid-stage products (Phase II)

• Early-stage product (Phase I)

• Pre-clinical and Discovery stage candidates

• Discontinued & Inactive candidates

• Route of Administration

Further Polycystic Kidney Disease product details are provided in the report. Download the Polycystic Kidney Disease pipeline report to learn more about the emerging Polycystic Kidney Disease therapies

Some of the key companies in the Polycystic Kidney Disease Therapeutics Market include:

Key companies developing therapies for Polycystic Kidney Disease are – Otsuka Pharmaceutical, Sanofi S.A, Reata Pharmaceuticals, Galapagos N.V, Janssen Pharmaceuticals, Regulus Therapeutics, Xortx Therapeutics, AceLink Therapeutics Inc., Pano Therapeutics, Inc., Exelixis, Inc., and others.

Polycystic Kidney Disease Pipeline Analysis:

The Polycystic Kidney Disease pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the treatment of Polycystic Kidney Disease with aggregate therapies developed by each company for the same.

• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Polycystic Kidney Disease Treatment.

• Polycystic Kidney Disease key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

• Polycystic Kidney Disease Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 

• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Polycystic Kidney Disease market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about Polycystic Kidney Disease drugs and therapies

Polycystic Kidney Disease Pipeline Market Drivers

• Advancements in Genetic Research, Innovative Treatment Approaches, Increased Funding and Investments, Rising Prevalence, Enhanced Diagnostic Techniques, Patient Advocacy and Awareness, are some of the important factors that are fueling the Polycystic Kidney Disease Market.

Polycystic Kidney Disease Pipeline Market Barriers

• However, High Development Costs, Regulatory Challenges, Limited Treatment Options, Complex Disease Mechanism, Side Effects and Safety Concerns, Market Competitionand other factors are creating obstacles in the Polycystic Kidney Disease Market growth.

Scope of Polycystic Kidney Disease Pipeline Drug Insight    

• Coverage: Global

• Key Polycystic Kidney Disease Companies: Hannover Medical School, Otsuka Pharmaceutical, Rege Nephro Co., Ltd., Otsuka Pharmaceutical, and others

• Key Polycystic Kidney Disease Therapies: Empagliflozin, Tolvaptan (OPC-41061), Tamibarotene, Tolvaptan Suspension, and others

• Polycystic Kidney Disease Therapeutic Assessment: Polycystic Kidney Disease current marketed and Polycystic Kidney Disease emerging therapies

• Polycystic Kidney Disease Market Dynamics: Polycystic Kidney Disease market drivers and Polycystic Kidney Disease market barriers 

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Table of Contents

1. Polycystic Kidney Disease Report Introduction

2. Polycystic Kidney Disease Executive Summary

3. Polycystic Kidney Disease Overview

4. Polycystic Kidney Disease- Analytical Perspective In-depth Commercial Assessment

5. Polycystic Kidney Disease Pipeline Therapeutics

6. Polycystic Kidney Disease Late Stage Products (Phase II/III)

7. Polycystic Kidney Disease Mid Stage Products (Phase II)

8. Polycystic Kidney Disease Early Stage Products (Phase I)

9. Polycystic Kidney Disease Preclinical Stage Products

10. Polycystic Kidney Disease Therapeutics Assessment

11. Polycystic Kidney Disease Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. Polycystic Kidney Disease Key Companies

14. Polycystic Kidney Disease Key Products

15. Polycystic Kidney Disease Unmet Needs

16 . Polycystic Kidney Disease Market Drivers and Barriers

17. Polycystic Kidney Disease Future Perspectives and Conclusion

18. Polycystic Kidney Disease Analyst Views

19. Appendix

20. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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