“Soft Tissue Sarcoma with Lung Metastasis Market” report has been added to DelveInsight

Soft Tissue Sarcoma with Lung Metastasis disease Overview

Soft tissue sarcoma (STS) are rare neoplasms that can develop in supporting or connective tissue, such as the muscle, nerves, tendons, blood vessels, and fatty and fibrous tissues. They commonly affect the arms, legs, and trunk. They also appear in the stomach and intestines (GIST) as well as behind the abdomen (retroperitoneal sarcomas) and the female reproductive system (gynecological sarcomas).

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Soft Tissue Sarcoma with Lung Metastasis Market: Geography Covered

• The United States

• EU5 (Germany, France, Italy, Spain, and the United Kingdom)

• Japan

Soft Tissue Sarcoma with Lung Metastasis Market Company

• Moleculin Biotech

Soft Tissue Sarcoma with Lung Metastasis Drug

• Annamycin

Soft Tissue Sarcoma with Lung Metastasis Market Report

Many STSs are associated with reciprocal translocations. Some forms of STS are associated with a variation (mutation) in a single oncogene, which is believed to drive the growth of cancer. An altered (mutation) oncogene may produce a protein that is ineffective, overproduced, or under-produced. Environmental factors that have been associated with STSs include radiation therapy and exposure to certain chemicals, including vinyl chloride, arsenic, and thorium dioxide.

Soft Tissue Sarcoma with Lung Metastasis Market Research Report

Although pulmonary metastases most commonly arise from primary tumors in the extremities, they may arise from almost any histologic variant or primary site. The most common site of distant spread of sarcomas is the lung. Thus, a new pulmonary nodule is likely to be metastatic if the primary malignancy was a sarcoma. Isolated pulmonary metastases occur in as many as 20% of patients diagnosed with soft tissue sarcoma as many as 40% in those with primary bone sarcoma. Metastases may infrequently occur in the skin, soft tissues, liver, and, in three percent of cases, the lymph nodes.

Soft Tissue Sarcoma with Lung Metastasis Treatment Market

The development of pulmonary metastases has a negative impact on prognosis, with most of the untreated patients dying within 6–11 months from diagnosis. Chemotherapy remains the standard treatment in metastatic sarcomas, but when it is performed alone, it shows poor improvement in survival rates. On the other hand, surgical therapy seems to be effective in prolonging survival among patients with resectable disease, with 5-year survival rates ranging from 15–50.9%.

Soft Tissue Sarcoma with Lung Metastasis Market Research

Metastasectomy and/or chemotherapy are the most common treatments offered to patients with metastatic sarcoma. Pulmonary metastasectomy, either video-assisted or through a formal thoracotomy, has been shown to increase overall survival in select populations of both osseous and soft tissue sarcoma patients.

Soft Tissue Sarcoma with Lung Metastasis Market Insights

Once the systemic metastatic disease develops, the prognosis is typically poor. Patients with extremity sarcomas are more likely to develop the distant metastatic disease as the initial site of recurrence. In contrast, those with retroperitoneal and visceral sarcomas tend to present local recurrence. The lung is the most frequent site of metastasis from soft-tissue sarcomas. Due to the relative resistance of sarcoma to either chemotherapy or radiotherapy, compared to other solid tumors, surgical management of pulmonary metastases has been a pivotal therapy in this disease.

Soft Tissue Sarcoma with Lung Metastasis Market Report Insights

• Patient Population

• Therapeutic Approaches

• STS with lung metastases Pipeline Analysis

• STS with lung metastases Market Size and Trends

• Market Opportunities

• Impact of upcoming Therapies

 

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Table of content

1 Key Insights

2 Executive Summary of STS with lung metastases

3 STS with lung metastases Market Overview at a Glance

4 Disease Background and Overview: STS with lung metastases

5 Case Reports

6 Epidemiology and Patient Population

7 United States Epidemiology

8 EU5 Epidemiology

9 Japan Epidemiology

10 Current Treatment and Medical Practices

10.3 Treatment Algorithm

11 Unmet needs

12 Emerging Drugs

13 Patient Journey

14 STS with lung metastases: 7MM Analysis

15 7MM Market Outlook

16 United States

17 EU-5 Countries

18 Japan

19 Market Drivers

20 Market Barriers

21 SWOT Analysis

22 Recognized Establishments

23 Appendix

24 DelveInsight Capabilities

25 Disclaimer

26 About DelveInsight

 

 

 

 

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