Spinal Cord Injury Pipeline

DelveInsight’s Spinal Cord Injury pipeline report comprehensive insights into 40+ companies and 40+ pipeline drugs in the Spinal Cord Injury pipeline landscape. It also includes clinical and nonclinical stage products in the pipeline drug profiles. It also assesses therapeutics based on product type, stage, route of administration, and molecule type.

Some of the Key Highlights from the Spinal Cord Injury Pipeline Report

• There are currently 40+ drugs in the pipeline for Spinal Cord Injury treatment.

• The Spinal Cord Injury pipeline comprises therapies that are in different stages of the clinical phase include KP-100IT, ES 135, PMZ-1620, MT 3921, AST-OPC1, FAB117-HC, NEU-2000, ALMB0166, KAND 567, Allogeneic stem cell therapy, and others and are expected to be available for Spinal Cord Injury treatment soon.

• Key pharmaceutical players which are evaluating their drug candidates for Spinal Cord Injury treatment include Kringle Pharma, Eusol Biotech, Pharmazz, Mitsubishi Tanabe Pharma, Lineage Cell Therapeutics, Histocell, AmKor Pharma, AlaMab therapeutics, Kancera, Athersys, among others.

• In September 2019, the Japanese Ministry of Health, Labour, and Welfare designated HGF (KP-100IT) as an orphan drug for acute spinal cord injury.

• GTX Medical and NeuroRecovery Technologies announced their merger in October 2019 to form a leading global company dedicated to developing novel neuromodulation therapies to improve the functional recovery of people with Spinal Cord Injuries (SCI). 

• Allogeneic stem cell therapy is being developed and investigated in preclinical studies by Athersys for Spinal Cord Injury treatment.

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Spinal Cord Injury: Overview

Traumatic damage to the spinal cord or nerves at the end of the spinal canal is referred to as spinal cord injury. This has an impact on the transmission of sensory and motor signals across the lesion site. Spinal cord injury is a debilitating neurological condition that has a significant socioeconomic impact on both affected individuals and the healthcare system. There are two types of spinal cord injuries: incomplete and complete injury.

Spinal Cord Injury Diagnosis

The goal of diagnosis is to determine the extent of neurological injury, the degree of residual sensory and motor function, and any complications. Imaging technology is an important part of the chronic spinal cord injury diagnostic process. MRI scans are the gold standard for imaging neurological tissues like the spinal cord, ligaments, discs, and soft tissues.

Spinal Cord Injury Treatment

Individuals suffering from Spinal Cord Injuries or disorders require multidisciplinary care management in order to achieve the best possible health outcomes. Chronic Spinal Cord Injury treatments aim to avoid or improve pathophysiological mechanisms such as glial scar formation, demyelination, and astrogliosis. 

Spinal Cord Injury Pipeline Analysis: Drug Profiles

KP-100IT: Kringle Pharma

Product Description

HGF (KP-100IT) protects neurons and stimulates axon elongation, therefore it could be used as a Spinal Cord Injury treatment. Currently, it is being developed and investigated in Phase III clinical trials for Spinal Cord Injury by Kringle Pharma. 

Phase III

NCT04475224: Kringle Pharma began a non-randomized, multicenter, and confirmatory study of KP-100IT intrathecal administration in subjects with acute spinal cord injury in July 2020. This is a non-randomized, multicenter, confirmatory trial in people with acute spinal cord injuries using intrathecal administration of KP-100IT, a code for HGF (Hepatocyte Growth Factor) formulation for intrathecal injection.

For more information on the emerging drugs and companies, visit Spinal Cord Injury Clinical Trials 

Spinal Cord Injury Pipeline Therapies and Key Companies 

• KP-100IT: Kringle Pharma

• ES 135: Eusol Biotech

• PMZ-1620: Pharmazz

• MT 3921: Mitsubishi Tanabe Pharma

• AST-OPC1: Lineage Cell Therapeutics

• FAB117-HC: Histocell

• NEU-2000: AmKor Pharma

• ALMB0166: AlaMab therapeutics

• KAND 567: Kancera

• Allogeneic stem cell therapy: Athersys

Spinal Cord Injury Therapeutics Assessment

• By Product Type

• Monotherapy

• Combination Therapy

• By Stage

• Discovery

• Pre-Clinical

• Phase I

• Phase II

• Phase III

• Pre-registration

• By Route of Administration

• Inhalation

• Intravenous

• Oral

• Subcutaneous

• By Molecule Type

• Small Molecule

• Stem Cell Therapy

• Gene Therapy

• Targets

• Immune System

• Multiple Kinase

• By Mechanism of Action

• Protease Inhibitors

• Immunomodulatory

Scope of the Report

Coverage: Global

Spinal Cord Injury Key Players: Kringle Pharma, Eusol Biotech, Pharmazz, Mitsubishi Tanabe Pharma, Lineage Cell Therapeutics, Histocell, AmKor Pharma, AlaMab therapeutics, Kancera, Athersys,among others

Spinal Cord Injury Pipeline Therapies: KP-100IT, ES 135, PMZ-1620, MT 3921, AST-OPC1, FAB117-HC, NEU-2000, ALMB0166, KAND 567, Allogeneic stem cell therapy, and others

Table of Contents 

For rich insights into Healthcare and Pharmaceutical News, visit Pharma, Healthcare, and Biotech Blog Posts

Key questions answered in the Spinal Cord Injury Pipeline Report

• What are the treatment options for Spinal Cord injury?

• How many pharmaceutical companies are working on cures for Spinal Cord injury?

• Which of these firms’ pharmaceuticals is the most widely used?

• How many Spinal Cord injury medications does each company make in total?

• How many drugs in the Spinal Cord injury pipeline are in the early, middle, or late phases of development?

• How many of the in-development therapies can be used alone or in combination with other treatments?

• What are the most important industry-industry and industry-academy collaborations, mergers and acquisitions, and licensing practices that affect Spinal Cord injury?

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About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing end-to-end comprehensive solutions to improve their performance. 

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