T cell immunoglobulin and ITIM domain (TIGIT) is an inhibitory receptor expressed on lymphocytes that was recently propelled under the spotlight as a major emerging target in cancer immunotherapy. TIGIT interacts with CD155 expressed on antigen‐presenting cells or tumor cells to down‐regulate T cell and natural killer (NK) cell functions. TIGIT has emerged as a key inhibitor of anti‐tumor responses that can hinder multiple steps of the cancer immunity cycle.
DelveInsights, “TIGIT Inhibitors Competitive landscape, 2023” report provides comprehensive insights about 18+ companies and TIGIT Inhibitors drugs in TIGIT inhibitors Competitive landscape. It covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
To know more about the TIGIT Inhibitors Competitive landscape report, click here: TIGIT Inhibitors Competitive Assessment
Key Takeaways from the TIGIT Inhibitors Competitive landscape report:
- Leading TIGIT Inhibitors Companies working in the market are Merck Sharp & Dohme, Bristol-Myers Squibb, BeiGene, Arcus Biosciences, iTeos Therapeutics, Mereo BioPharma, Phio Pharmaceuticals, Bio-Thera Solutions, Compugen.
- Key TIGIT Inhibitors therapies in various stages of development include Ociperlimab+ Tislelizumab, MK-7684A, Domvanalimab+ Zimberelimab, BMS 986207, BAT-6005, AGEN 1777+ PD-1 Inhibitor, PH 804, TSRF-786-C and Others.
- In December 2021, Bio-Thera Solutions a commercial-stage pharmaceutical company announced that dosing has begun in Phase I clinical study to compare the pharmacokinetics and safety of BAT6005, a monoclonal antibody targeting TIGIT in cancer patient volunteers.
DelveInsight’s TIGIT Inhibitors Report covers around 200+ products under different phases of clinical development like
- Assessment by TIGIT Inhibitors Product Type
- Assessment by Stage and Product Type of TIGIT Inhibitors
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration of TIGIT Inhibitors
- Assessment by TIGIT Inhibitors Molecule Type
- Assessment by Stage and Molecule Type of TIGIT Inhibitors
Emerging TIGIT Inhibitors Drugs Under Different Phases of Clinical Development Include:
Some of the TIGIT Inhibitors therapies are Ociperlimab, MK-7684A (pembrolizumab/vibostolimab), BMS 986207, BAT-6005 and Many Others.
Further TIGIT Inhibitors product details are provided in the report. Download the TIGIT Inhibitors Pipeline report to learn more about the emerging TIGIT Inhibitors therapies at: TIGIT Inhibitors Clinical Trials and Developments
Drug/Drug Combination |
Company Name |
Phase |
Indication |
Ociperlimab + Tislelizumab |
BeiGene |
Phase III |
Non-small Cell Lung Cancer |
MK-7684A (pembrolizumab/vibostolimab) |
Merck Sharp & Dohme |
Phase III |
Non-Small-Cell Lung Carcinoma |
Domvanalimab + Zimberelimab |
Arcus Biosciences |
Phase III |
Non-Small Cell Lung Cancer |
BMS 986207 |
Bristol-Myers Squibb |
Phase II |
Non-Small Cell Lung Cancer |
BAT-6005 |
Bio-Thera Solutions |
Phase I |
Locally Advanced or Metastatic Solid Tumors |
AGEN 1777 + PD-1 Inhibitor |
Agenus |
Phase I |
Advanced Solid Tumors |
PH 804 |
Phio Pharmaceuticals |
Preclinical |
Solid Tumors |
TSRF-786-C |
Tasrif Pharmaceutical |
Preclinical |
Cancer |
Key companies in the TIGIT Inhibitors Therapeutics Market:
Some of the TIGIT Inhibitors Companies working in the market are Merck Sharp & Dohme, Bristol-Myers Squibb, BeiGene, Arcus Biosciences, iTeos Therapeutics, Mereo BioPharma, Phio Pharmaceuticals, Bio-Thera Solutions, Compugen.
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Table of Content (TOC)
1. TIGIT Inhibitors Pipeline Report Introduction
2. TIGIT Inhibitors Pipeline Report Executive Summary
3. TIGIT Inhibitors Pipeline: Overview
4. Analytical Perspective In-depth Commercial Assessment
5. TIGIT Inhibitors Clinical Trial Therapeutics
6. TIGIT Inhibitors Pipeline: Late Stage Products (Pre-registration)
7. TIGIT Inhibitors Pipeline: Late Stage Products (Phase III)
8. TIGIT Inhibitors Pipeline: Mid Stage Products (Phase II)
9. TIGIT Inhibitors Pipeline: Early Stage Products (Phase I)
10. TIGIT Inhibitors Pipeline Therapeutic Assessment
11. Inactive Products in the TIGIT Inhibitors Pipeline
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Key TIGIT Inhibitors Companies
14. Key Products in the TIGIT Inhibitors Pipeline
15. Unmet Needs
16. TIGIT Inhibitors Market Drivers and Barriers
17. Future Perspectives and Conclusion
18. Analyst Views
19. Appendix
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