DelveInsight’s “Urea Cycle Disorders Market Insights, Epidemiology and Market Forecast 2030“ report delivers an in-depth understanding of the Urea Cycle Disorders, historical and forecasted epidemiology as well as the Urea Cycle Disorders market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Geography Covered
- The United States
- EU5 (Germany, France, Italy, Spain, and the United Kingdom)
- Japan
Study Period: 2017-2030
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A Urea Cycle Disorder (UCD) is a genetic disorder that results in a deficiency of some major enzymes in the urea cycle. These enzymes are responsible for removing ammonia from the blood stream. The urea cycle involves a series of biochemical steps in which nitrogen, a waste product of protein metabolism, is changed to a compound called urea and removed from the blood. Normally, the urea is removed from the body through the urine. In urea cycle disorders, nitrogen builds up in the blood in the form of ammonia, a highly toxic substance, resulting in hyperammonemia (elevated blood ammonia). Ammonia then reaches the brain through the blood, where it can cause irreversible brain damage, coma, and/or death. The onset and severity of urea cycle disorders is highly variable. The severity correlates with the amount of urea cycle enzyme function.
A few of the enzymes which are involved in the Urea Cycle Disorder, collectively known as inborn errors of urea synthesis, or urea cycle enzyme defects; each is referred to by the initials of the missing enzyme: CPS1 (Carbamoyl Phosphate Synthetase), NAGS (N-Acetylglutamate Synthetase), OTC Deficiency (Ornithine Transcarbamylase), AS (Argininosuccinic Acid Synthetase (Citrullinemia)), ASL (Argininosuccinate Lyase (Argininosuccinic Aciduria)), and AG (Arginase).
Urea Cycle Disorders Disease Understanding and Treatment Algorithm
The DelveInsight Urea Cycle Disorders market report gives a thorough understanding of the Urea Cycle Disorders by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis and treatment.
Urea Cycle Disorders Epidemiology
The Urea Cycle Disorders epidemiology division provide insights about historical and current Urea Cycle Disorders patient pool and forecasted trend for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Urea Cycle Disorders Drug Chapters
Drug chapter segment of the Urea Cycle Disorders report encloses the detailed analysis of Urea Cycle Disorders marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the Urea Cycle Disorders clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.
Urea Cycle Disorders Market Outlook
The Urea Cycle Disorders market outlook of the report helps to build the detailed comprehension of the historic, current, and forecasted Urea Cycle Disorders market trends by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.
According to DelveInsight, Urea Cycle Disorders market in 7MM is expected to change in the study period 2017-2030.
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Scope of the Report
- The report covers the descriptive overview of Urea Cycle Disorders, explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
- Comprehensive insight has been provided into the Urea Cycle Disorders epidemiology and treatment in the 7MM
- Additionally, an all-inclusive account of both the current and emerging therapies for Urea Cycle Disorders are provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
- A detailed review of Urea Cycle Disorders market; historical and forecasted is included in the report, covering drug outreach in the 7MM
- The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Urea Cycle Disorders market
Table of contents:
1. Key Insights
2. Executive Summary of Urea Cycle Disorders
3. Competitive Intelligence Analysis for Urea Cycle Disorders
4. Urea Cycle Disorders: Market Overview at a Glance
4.1. Urea Cycle Disorders Total Market Share (%) Distribution in 2017
4.2. Urea Cycle Disorders Total Market Share (%) Distribution in 2030
5. Urea Cycle Disorders: Disease Background and Overview
5.1. Introduction
5.2. Sign and Symptoms
5.3. Pathophysiology
5.4. Risk Factors
5.5. Diagnosis
6. Patient Journey
7. Urea Cycle Disorders Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
8.1. Urea Cycle Disorders Treatment and Management
8.2. Urea Cycle Disorders Treatment Algorithm
9. Unmet Needs
10. Key Endpoints of Urea Cycle Disorders Treatment
11. Marketed Products
11.1. List of Marketed Products in the 7MM
11.2. Drug Name: Company Name
11.2.1. Product Description
11.2.2. Regulatory Milestones
11.2.3. Other Developmental Activities
11.2.4. Pivotal Clinical Trials
11.2.5. Summary of Pivotal Clinical Trial
List to be continued in report
12. Emerging Therapies
12.1. Key Cross
12.2. Drug Name: Company Name
12.2.1. Product Description
12.2.2. Other Developmental Activities
12.2.3. Clinical Development
12.2.4. Safety and Efficacy
12.2.5. Product Profile
List to be continued in report
13. Urea Cycle Disorders: Seven Major Market Analysis
13.1. Key Findings
13.2. Urea Cycle Disorders Market Size in 7MM
13.3. Urea Cycle Disorders Market Size by Therapies in the 7MM
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Urea Cycle Disorders
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
20.1. Bibliography
20.2. Report Methodology
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
*The table of contents is not exhaustive; the final content may vary.
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