DelveInsight’s, “Uterine Leiomyosarcoma Pipeline Insight 2023” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in the Uterine Leiomyosarcoma pipeline landscape. It covers the Uterine Leiomyosarcoma pipeline drug profiles, including Uterine Leiomyosarcoma clinical trials and nonclinical stage products. It also covers the Uterine Leiomyosarcoma therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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Key Takeaways from the Uterine Leiomyosarcoma Pipeline Report
- DelveInsight’s Uterine Leiomyosarcoma Pipeline report depicts a robust space with 5+ active players working to develop 5+ pipeline therapies for Uterine Leiomyosarcoma.
- The leading Uterine Leiomyosarcoma Companies include Novartis, PharmMar, and Others
- Promising Uterine Leiomyosarcoma Pipeline Therapies include Trabectedin, Letrozole, and others.
- The primary form of treatment for a Uterine Leiomyosarcoma is surgical removal of the entire tumor and any affected tissue. Total surgical removal of the uterus (hysterectomy) is usually performed. Anti-cancer drugs used alone or combination (chemotherapy) and radiation therapy have been used to treat individuals with leiomyosarcoma following surgery (adjuvant therapy) with limited benefit. Leiomyosarcomas have a high risk of recurrence, individuals should be examined routinely after surgery.
- The Uterine Leiomyosarcoma companies and academics are working to assess challenges and seek opportunities that could influence Uterine Leiomyosarcoma R&D. The Uterine Leiomyosarcoma therapies under development are focused on novel approaches to treat/improve Uterine Leiomyosarcoma.
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Uterine Leiomyosarcoma Overview
A Uterine Leiomyosarcoma (ULMS) is a rare malignant (cancerous) tumor that arises from the smooth muscle lining the walls of the uterus (myometrium). Leiomyosarcoma is classified as a soft tissue sarcoma. Sarcomas are malignant tumors that arise from the connective tissue, which connects, supports and surrounds various structures and organs in the body. Soft tissue includes fat, muscle, never, tendons, tissue surrounding the joints (synovial tissue), and blood and lymph vessels. The exact cause of leiomyosarcoma, including Uterine Leiomyosarcoma, is unknown.
Uterine Leiomyosarcoma Emerging Drugs Profile
- Trabectedin: PharmMar
Yondelis® (trabectedin) is a novel, synthetically produced antitumor agent originally isolated from Ecteinascidia turbinata, a type of sea squirt. Yondelis® exerts its anticancer effects primarily by inhibiting active transcription, a type of gene expression on which proliferating cancer cells are particularly dependent.
- Letrozole: Novartis
Letrozole is a non-steroidal type II aromatase inhibitor. It blocks the active site, and therefore the electron transfer chain of CYP19A1. This competitive inhibition prevents the conversion of androgens to estrogen. This action leads to a reduction in uterine weight and elevated leuteinizing hormone.8 In postmenopausal women, the action of aromatase is responsible for the majority of estrogen production. With reduced availability of estrogen, estrogen-dependant tumors regress. Third generation aromatase inhibitors do not significantly affect cortisol, aldosterone, and thyroxine levels. Currently, in phase II of clinical trials.
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Uterine Leiomyosarcoma Pipeline Therapeutics Assessment
There are approx. 5+ key companies which are developing the therapies for Uterine Leiomyosarcoma. The companies which have their Uterine Leiomyosarcoma drug candidates in the mid to advanced stage, i.e. phase III and Phase II include, Novartis and others.
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Scope of the Uterine Leiomyosarcoma Pipeline Report
- Coverage- Global
- Uterine Leiomyosarcoma Companies- Novartis, PharmMar, and Others
- Uterine Leiomyosarcoma Pipeline Therapies- Trabectedin, Letrozole, and others
- Uterine Leiomyosarcoma Pipeline Segmentation: Product Type, Molecule Type, Route of Administration
Got Queries? Find out the related information on Uterine Leiomyosarcoma Mergers and acquisitions, Uterine Leiomyosarcoma Licensing Activities @ Uterine Leiomyosarcoma Emerging Drugs, and Recent Trends
Table of Content
- Introduction
- Executive Summary
- Uterine Leiomyosarcoma: Overview
- Pipeline Therapeutics
- Therapeutic Assessment
- Uterine Leiomyosarcoma – DelveInsight’s Analytical Perspective
- In-depth Commercial Assessment
- Uterine Leiomyosarcoma Collaboration Deals
- Late Stage Products (Phase III)
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- Letrozole: Novartis
- Drug profiles in the detailed report…..
- Pre-clinical and Discovery Stage Products
- Drug profiles in the detailed report…..
- Inactive Products
- Uterine Leiomyosarcoma Key Companies
- Uterine Leiomyosarcoma Key Products
- Uterine Leiomyosarcoma- Unmet Needs
- Uterine Leiomyosarcoma- Market Drivers and Barriers
- Uterine Leiomyosarcoma- Future Perspectives and Conclusion
- Uterine Leiomyosarcoma Analyst Views
- Uterine Leiomyosarcoma Key Companies
- Appendix
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